Modeling Chemotherapeutic Neurotoxicity with Human Induced Pluripotent Stem Cell-Derived Neuronal Cells

TNF-α-mediated JNK activation in the dorsal root ganglion neurons contributes to Bortezomib-induced peripheral neuropathy

(2014) Jie Zhang et al.   BRAIN BEHAVIOR AND IMMUNITY

Integrating Cell-Based and Clinical Genome-Wide Studies to Identify Genetic Variants Contributing to Treatment Failure in Neuroblastoma Patients

(2014) N Pinto et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline

(2014) Dawn L. Hershman et al.   JOURNAL OF CLINICAL ONCOLOGY

Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes

(2014) Alice Matimba et al.   PHARMACOGENOMICS

Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance)

(2014) A Chhibber et al.   PHARMACOGENOMICS JOURNAL

Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles

(2014) L. M. Zasadil et al.   Science Translational Medicine

Genetic Background Drives Transcriptional Variation in Human Induced Pluripotent Stem Cells

(2014) Foad Rouhani et al.   PLoS Genetics

Prevention and treatment of chemotherapy-induced peripheral neuropathy

(2013) Jennifer Piccolo et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients

(2013) E. R. Gamazon et al.   BLOOD

Nutraceuticals and chemotherapy induced peripheral neuropathy (CIPN): A systematic review

(2013) Janet M. Schloss et al.   CLINICAL NUTRITION

Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy

(2013) Ellen M. Lavoie Smith et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The search for treatments to reduce chemotherapy-induced peripheral neuropathy

(2013) Deirdre R. Pachman et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy

(2013) Luis J Leandro-García et al.   JOURNAL OF MEDICAL GENETICS

Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: Implications for chemotherapy-induced peripheral neuropathy

(2013) Nichole E. LaPointe et al.   NEUROTOXICOLOGY

Regulatory Polymorphisms in  -Tubulin IIa Are Associated with Paclitaxel-Induced Peripheral Neuropathy

(2012) L. J. Leandro-Garcia et al.   CLINICAL CANCER RESEARCH

A Genome-Wide Association Study Identifies Novel Loci for Paclitaxel-Induced Sensory Peripheral Neuropathy in CALGB 40101

(2012) R. M. Baldwin et al.   CLINICAL CANCER RESEARCH

Integration of Cell Line and Clinical Trial Genome-Wide Analyses Supports a Polygenic Architecture of Paclitaxel-Induced Sensory Peripheral Neuropathy

(2012) H. E. Wheeler et al.   CLINICAL CANCER RESEARCH

Leveraging Epidemiology and Clinical Studies of Cancer Outcomes: Recommendations and Opportunities for Translational Research

(2012) Joanne W. Elena et al.   JNCI-Journal of the National Cancer Institute

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Cancer pharmacogenomics: strategies and challenges

(2012) Heather E. Wheeler et al.   NATURE REVIEWS GENETICS

Animal Models of Peripheral Neuropathies

(2012) Ahmet Höke   Neurotherapeutics

Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel

(2012) Uchenna O. Njiaju et al.   Pharmacogenetics and Genomics

Human lymphoblastoid B-cell lines reprogrammed to EBV-free induced pluripotent stem cells

(2011) D. Rajesh et al.   BLOOD

LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress

(2011) Ha Nam Nguyen et al.   Cell Stem Cell

Chemotherapy-induced peripheral neurotoxicity (CIPN): An update

(2011) Andreas A. Argyriou et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Natural History of Paclitaxel-Associated Acute Pain Syndrome: Prospective Cohort Study NCCTG N08C1

(2011) Charles L. Loprinzi et al.   JOURNAL OF CLINICAL ONCOLOGY

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

(2011) Sergiu P Paşca et al.   NATURE MEDICINE

Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation

(2011) Heather E Wheeler et al.   PHARMACOGENOMICS

Chemotherapy-Induced Peripheral Neurotoxicity assessment: A critical revision of the currently available tools

(2010) Guido Cavaletti et al.   EUROPEAN JOURNAL OF CANCER

Neurophysiological and neuropathological characterization of new murine models of chemotherapy-induced chronic peripheral neuropathies

(2010) V.A. Carozzi et al.   EXPERIMENTAL NEUROLOGY

Genome-Wide Associations and Functional Genomic Studies of Musculoskeletal Adverse Events in Women Receiving Aromatase Inhibitors

(2010) James N. Ingle et al.   JOURNAL OF CLINICAL ONCOLOGY

Chemotherapy-induced peripheral neurotoxicity

(2010) Guido Cavaletti et al.   Nature Reviews Neurology

Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes

(2010) Stormy J. Chamberlain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models of chemotherapy-evoked painful peripheral neuropathies

(2009) Nicolas Authier et al.   Neurotherapeutics

Implications of Apurinic/Apyrimidinic Endonuclease in Reactive Oxygen Signaling Response after Cisplatin Treatment of Dorsal Root Ganglion Neurons

(2008) Y. Jiang et al.   CANCER RESEARCH

Chemotherapy-induced peripheral neuropathy: Prevention and treatment strategies

(2008) Sherry Wolf et al.   EUROPEAN JOURNAL OF CANCER