A Predictive In Vitro Model of the Impact of Drugs with Anticholinergic Properties on Human Neuronal and Astrocytic Systems

Effect of medications with anti-cholinergic properties on cognitive function, delirium, physical function and mortality: a systematic review

(2014) C. Fox et al.   AGE AND AGEING

Methodological Challenges in Determining Longitudinal Associations Between Anticholinergic Drug Use and Incident Cognitive Decline

(2014) Mandavi Kashyap et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

(2014) Ethan S. Lippmann et al.   Scientific Reports

Anticholinergic Drug Burden in Older People's Brain - How well is it Measured?

(2013) Hege Kersten et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Anticholinergic Component of the Drug Burden Index and the Anticholinergic Drug Scale as Measures of Anticholinergic Exposure in Older People in New Zealand: A Population-Level Study

(2013) Sujita W. Narayan et al.   DRUGS & AGING

Therapeutic doses of antidepressants are projected not to inhibit human α4β2 nicotinic acetylcholine receptors

(2013) Mark L. Weber et al.   NEUROPHARMACOLOGY

Activity and metabolism-related Ca2+ and mitochondrial dynamics in co-cultured human fetal cortical neurons and astrocytes

(2013) W. Fu et al.   NEUROSCIENCE

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

(2013) Swetha Vijayaraghavan et al.   PLoS One

Association of Anticholinergic Burden with Cognitive and Functional Status in a Cohort of Hospitalized Elderly: Comparison of the Anticholinergic Cognitive Burden Scale and Anticholinergic Risk Scale

(2012) Luca Pasina et al.   DRUGS & AGING

The Use of Antidepressants in Belgian Nursing Homes

(2012) Jolyce Bourgeois et al.   DRUGS & AGING

Blood–Brain Barrier Permeation and Efflux Exclusion of Anticholinergics Used in the Treatment of Overactive Bladder

(2012) Michael B. Chancellor et al.   DRUGS & AGING

P-Glycoprotein Function at the Blood–Brain Barrier: Effects of Age and Gender

(2012) Daniëlle M. E. van Assema et al.   MOLECULAR IMAGING AND BIOLOGY

NT2 Derived Neuronal and Astrocytic Network Signalling

(2012) Eric J. Hill et al.   PLoS One

Astrocytes Mediate In Vivo Cholinergic-Induced Synaptic Plasticity

(2012) Marta Navarrete et al.   PLOS BIOLOGY

Steady-State Pharmacokinetics of Once-Daily Cyclobenzaprine Extended Release: A Randomized, Double-Blind, 2-Period Crossover Study in Healthy Volunteers

(2011) Mona Darwish et al.   CLINICAL THERAPEUTICS

Anticholinergic Medication Use and Cognitive Impairment in the Older Population: The Medical Research Council Cognitive Function and Ageing Study

(2011) Chris Fox et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Regional Differentiation of Retinoic Acid-Induced Human Pluripotent Embryonic Carcinoma Stem Cell Neurons

(2011) Dennis E. Coyle et al.   PLoS One

Assessing the adverse effects of antimuscarinic drugs in older patients: which way forward?

(2011) Arduino A Mangoni   Expert Review of Clinical Pharmacology

Feasibility Study of a Systematic Approach for Discontinuation of Multiple Medications in Older Adults

(2010) Doron Garfinkel et al.   ARCHIVES OF INTERNAL MEDICINE

Apoptosis as a specific biomarker of diazinon toxicity in NTera2-D1 cells

(2010) M.G. Aluigi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Association of Anticholinergic Drugs with Hospitalization and Mortality among Older Cardiovascular Patients

(2010) Juho Uusvaara et al.   DRUGS & AGING

Single-Cell ELISA and Flow Cytometry as Methods for Highlighting Potential Neuronal and Astrocytic Toxicant Specificity

(2010) E. K. Woehrling et al.   NEUROTOXICITY RESEARCH

Synergy Between Pairs of Competitive Antagonists at Adult Human Muscle Acetylcholine Receptors

(2009) Man Liu et al.   ANESTHESIA AND ANALGESIA

Cellular phenotypes of human model neurons (NT2) after differentiation in aggregate culture

(2009) Grzegorz Podrygajlo et al.   CELL AND TISSUE RESEARCH

Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation

(2009) Rodrigo R Resende et al.   Cell Communication and Signaling

Integration of human model neurons (NT2) into embryonic chick nervous system

(2009) Grzegorz Podrygajlo et al.   DEVELOPMENTAL DYNAMICS

Evaluation of the Importance of Astrocytes When Screening for Acute Toxicity in Neuronal Cell Systems

(2009) E. K. Woehrling et al.   NEUROTOXICITY RESEARCH

The Anticholinergic Risk Scale and Anticholinergic Adverse Effects in Older Persons

(2008) James L. Rudolph   ARCHIVES OF INTERNAL MEDICINE

Serum anticholinergic activity and cerebral cholinergic dysfunction: An EEG study in frail elderly with and without delirium

(2008) Christine Thomas et al.   BMC NEUROSCIENCE

The Effects of Polypharmacy in Older Adults

(2008) SN Hilmer et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Unbound Drug Concentration in Brain Homogenate and Cerebral Spinal Fluid at Steady State as a Surrogate for Unbound Concentration in Brain Interstitial Fluid

(2008) X. Liu et al.   DRUG METABOLISM AND DISPOSITION

Anticholinergic Activity of 107 Medications Commonly Used by Older Adults

(2008) Marci L. Chew et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Differentiating human NT2/D1 neurospheres as a versatile in vitro 3D model system for developmental neurotoxicity testing

(2008) E.J. Hill et al.   TOXICOLOGY