Article
Cardiac & Cardiovascular Systems
Jouke P. Bokma, Tal Geva, Lynn A. Sleeper, Ji Hae Lee, Minmin Lu, Tehila Sompolinsky, Sonya V. Babu-Narayan, Rachel M. Wald, Barbara J. M. Mulder, Anne Marie Valente
Summary: The study aimed to determine whether pulmonary valve replacement (PVR) is associated with improved survival and freedom from sustained ventricular tachycardia (VT) in patients with repaired tetralogy of Fallot (rTOF). The results showed that patients who received PVR had a lower risk of death or sustained VT compared to those who did not receive PVR.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Samuel Blais, Ariane Marelli, Alain Vanasse, Nagib Dahdah, Adrian Dancea, Christian Drolet, Frederic Dallaire
Summary: This study compared 30-year outcomes of tetralogy of Fallot (TOF) repair after valve-sparing (VS) procedures vs transannular patch (TAP) procedures. The findings showed that patients who underwent VS procedures had increased 30-year survival, fewer cardiovascular reinterventions, and fewer pulmonary valve replacements (PVRs) compared to those who underwent TAP procedures.
Article
Cardiac & Cardiovascular Systems
Anjali Chelliah, Anita J. Moon-Grady, Shabnam Peyvandi, Joanne S. Chiu, James E. Bost, David Schidlow, Sheila J. Carroll, Brooke Davey, Allison Divanovic, Lisa Hornberger, Lisa W. Howley, Ann Kavanaugh-McHugh, John P. Kovalchin, Stephanie M. Levasseur, Christopher L. Lindblade, Shaine A. Morris, Deliwe Ngwezi, Jay D. Pruetz, Michael D. Puchalski, Jack Rychik, Cyrus Samai, Theresa A. Tacy, Wayne Tworetzky, Margaret M. Vernon, Jay Yeh, Mary T. Donofrio
Summary: Perinatal mortality in tetralogy of Fallot with absent pulmonary valve remains high, with an overall survival of 64% in fetuses with intention to treat. Right ventricular dysfunction independently predicts overall mortality, while left ventricular dysfunction independently predicts fetal mortality and may influence prenatal management and delivery planning. Medistinal shift may reflect secondary effects of airway obstruction and abnormal lung development, associated with increased mortality.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Christopher J. Petit, Andrew C. Glatz, Andrew B. Goldstone, Mark A. Law, Jennifer C. Romano, Shiraz A. Maskatia, Paul J. Chai, Jeffrey D. Zampi, Jeffery J. Meadows, George T. Nicholson, Shabana Shahanavaz, Athar M. Qureshi, Courtney E. Mccracken, Christopher E. Mascio, Sarosh P. Batlivala, Ivor B. Asztalos, Steven J. Healan, Justin D. Smith, Joelle A. Pettus, Asaad Beshish, James E. B. Raulston, Krissie M. Hock, Amy L. Pajk, Bryan H. Goldstein
Summary: This study aimed to quantify the impact of hypoplastic pulmonary arteries (hPA) on outcomes in neonates with symptomatic tetralogy of Fallot (sTOF), and measure the impact of management strategy on pulmonary artery (PA) growth. The study included 542 neonates and found that the presence of hPA did not increase the hazard of mortality or reintervention after definitive repair, and the hPA cohort showed superior PA growth.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Kang Yi, Dan Wang, Jianguo Xu, Xin Zhang, Wenxin Wang, Jie Gao, Wei Wang, Tao You, Jinhui Tian
Summary: This study evaluated the efficacy and safety of different surgical strategies in preserving pulmonary valve function in ToF patients. Results indicated that IBPV, pulmonary valve reconstruction, and commissurotomy and PCA can be performed during surgery based on the developmental status and anatomical characteristics of the patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Ahmed Farghal A. Mohammed, Michael Frick, Gunter Kerst, Nima Hatam, Mohamed-Adel F. Elgamal, Karam M. Essa, Hedwig H. Hoevels-Guerich, Jaime F. Vazquez-Jimenez, Rashad Zayat
Summary: The study revealed a high prevalence of proximal aortic dilatation after TOF repair, with factors such as late corrective surgery, palliative shunt, and aortic valve regurgitation being associated with the dilatation. Pulmonary valve replacement and higher AR fraction were identified as independent predictors of AAo dilatation.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Maria Gusseva, Tarique Hussain, Camille Hancock Friesen, Philippe Moireau, Animesh Tandon, Cecile Patte, Martin Genet, Keren Hasbani, Gerald Greil, Dominique Chapelle, Radomir Chabiniok
Summary: This study utilized a biomechanical model to evaluate rTOF patients and found that residual RVOTO has a greater impact on cardiac health. Individualized modeling is helpful in predicting the heart's response to percutaneous pulmonary valve replacement.
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Jeffery J. Meadows, Holly Bauser-Heaton, Christopher J. Petit, Bryan H. Goldstein, Athar M. Qureshi, Courtney E. McCracken, Michael S. Kelleman, George T. Nicholson, Mark A. Law, Jeffrey D. Zampi, Shabana Shahanavaz, Paul J. Chai, Jennifer C. Romano, Sarosh P. Batlivala, Shiraz A. Maskatia, Ivor B. Asztalos, Lindsay Eilers, Alicia M. Kamsheh, Steven J. Healan, Justin D. Smith, R. Allen Ligon, Andrew Dailey-Schwartz, Joelle A. Pettus, Amy L. Pajk, Andrew C. Glatz, Christopher E. Mascio
Summary: This study retrospectively compared the outcomes of primary repair (PR) and staged repair (SR) in neonates with tetralogy of Fallot and pulmonary atresia (TOF/PA). The results showed that SR was more common in higher-risk patients. The mortality rate was similar between SR and PR, but PR had advantages in perioperative morbidities, reintervention rates, and right pulmonary artery growth, while SR allowed for larger initial conduit implantation.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Medicine, General & Internal
Christopher DeZorzi, Anais Marenco, Anne Marie Valente
Summary: Tricuspid regurgitation is a significant finding in patients who have undergone repair for tetralogy of Fallot, and it can have primary or secondary causes. Moderate or severe tricuspid regurgitation is associated with a higher occurrence of atrial tachyarrhythmias in these patients. The optimal timing for tricuspid valve intervention during pulmonary valve replacement in repaired tetralogy of Fallot patients remains uncertain.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Giulio Calcagni, Camilla Calvieri, Anwar Baban, Francesco Bianco, Rosaria Barracano, Massimo Caputo, Andrea Madrigali, Stefani Silva Kikina, Marco Alfonso Perrone, Maria Cristina Digilio, Marco Pozzi, Aurelio Secinaro, Berardo Sarubbi, Lorenzo Galletti, Maria Giulia Gagliardi, Andrea de Zorzi, Fabrizio Drago, Benedetta Leonardi
Summary: This study reveals that genetic syndromes, particularly Down syndrome, have a significant impact on cardiac magnetic resonance imaging parameters, specifically left ventricular dysfunction, following the repair of Tetralogy of Fallot. The patients with genetic syndromes were older at repair and younger at pulmonary valve replacement compared to non-syndromic patients. The presence of genetic syndromes was strongly associated with left ventricular dysfunction.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Mei-Hwan Wu, Jou-Kou Wang, Sheunn-Nan Chiu, Chun-Wei Lu, Ming-Tai Lin, Chun-An Chen, Wei-Chieh Tseng
Summary: This study conducted a retrospective study on repaired tetralogy of Fallot patients, and found that the risk of ventricular tachyarrhythmia/sudden cardiac arrest and the need for PVR increased with age.
Article
Cardiac & Cardiovascular Systems
Michael L. O'Byrne, Andrew C. Glatz, Yuan-shung Huang, Michael S. Kelleman, Christopher J. Petit, Athar M. Qureshi, Shabana Shahanavaz, George T. Nicholson, Shawn Batlivala, Jeffery J. Meadows, Jeffrey D. Zampi, Mark A. Law, Jennifer C. Romano, Christopher E. Mascio, Paul J. Chai, Shiraz Maskatia, Ivor B. Asztalos, Asaad Beshish, Joelle Pettus, Amy L. Pajk, Steven J. Healan, Lindsay F. Eilers, Taylor Merritt, Courtney E. McCracken, Bryan H. Goldstein
Summary: This study compares the economic costs of primary repair (PR) and staged repair (SR) in neonates with symptomatic tetralogy of Fallot (sTOF). The results show that PR is associated with lower total costs, cost per day alive, and department-level costs compared to SR.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Alqasem Fuad H. Al Mosa, Sreenath Madathil, Pierre-Luc Bernier, Christo Tchervenkov
Summary: This study investigated the long-term outcomes of late pulmonary valve replacement in patients with repaired tetralogy of Fallot. The Contegra prosthesis had a higher risk of late adverse events with higher pulmonary valve gradients compared to other prostheses.
WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY
(2021)
Article
Anesthesiology
Kwannapas Saengsin, Francesca Sperotto, Minmin Lu, Julia Garcia Mancebo, Elizabeth Sacco, Manasee Godsay, James A. DiNardo, John N. Kheir
Summary: The use of milrinone within the first 72 hours following TOF repair is associated with more frequent administration of volume, a slower recovery of heart rate, and lower blood pressure, but is not associated with improved cardiac output.
ANESTHESIA AND ANALGESIA
(2023)
Article
Cardiac & Cardiovascular Systems
Bryan H. Goldstein, Christopher J. Petit, Athar M. Qureshi, Courtney E. McCracken, Michael S. Kelleman, George T. Nicholson, Mark A. Law, Jeffery J. Meadows, Jeffrey D. Zampi, Shabana Shahanavaz, Christopher E. Mascio, Paul J. Chai, Jennifer C. Romano, Sarosh P. Batlivala, Shiraz A. Maskatia, Ivor B. Asztalos, Alicia M. Kamsheh, Steven J. Healan, Justin D. Smith, R. Allen Ligon, Joelle A. Pettus, Sarina Juma, James E. B. Raulston, Krissie M. Hock, Amy L. Pajk, Lindsay F. Eilers, Hala Q. Khan, Taylor C. Merritt, Matthew Canter, Stephan Juergensen, Fatuma-Ayaan Rinderknecht, Holly Bauser-Heaton, Andrew C. Glatz
Summary: In this multicenter comparison of staged repair (SR) and primary repair (PR) for neonates with symptomatic tetralogy of Fallot (sTOF), early mortality and neonatal morbidity were lower in the SR group, while cumulative morbidity and reinterventions favored the PR group, suggesting potential benefits to each strategy.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Critical Care Medicine
Siva P. Namachivayam, Warwick Butt, Johnny Millar, Igor E. Konstantinov, Cattram Nguyen, Yves d'Udekem
PEDIATRIC CRITICAL CARE MEDICINE
(2019)
Article
Hematology
Joanna Y. Huang, Vera Ignjatovic, Bennett J. Sheridan, Jacob Mathew, Yves D'Udekem, Johann Brink, Rebecca Barton, Gabrielle Callea, Dominique Morsman, Susan Donath, Stephen Opat, Paul Monagle
THROMBOSIS RESEARCH
(2019)
Article
Cardiac & Cardiovascular Systems
David P. Newland, Chin L. Poh, Diana Zannino, Patrick Elias, Christian P. Brizard, Kirsten Finucane, David S. Winlaw, Yves d'Udekem
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2019)
Article
Cardiac & Cardiovascular Systems
Melissa G. Y. Lee, Sonya V. Babu-Narayan, Aleksander Kempny, Anselm Uebing, Claudia Montanaro, Darryl F. Shore, Yves d'Udekem, Michael A. Gatzoulis
Editorial Material
Cardiac & Cardiovascular Systems
Yves d'Udekem, Chin L. Poh
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Tomislav Santro, Yves d'Udekem, Diana Zannino, Ben Hobbes, Igor E. Konstantinov, Christian Brizard, Johann Brink
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2019)
Article
Oncology
Chantal Attard, Joanna Huang, Fiona Newall, Paul Monagle, Yves d'Udekem, Vera Ignjatovic
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Emily Moroney, Diana Zannino, Rachael Cordina, Thomas Gentles, Yves d'Udekem, Dominica Zentner
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Tyson A. Fricke, Samantha Donaldson, James R. Schneider, Samuel Menahem, Yves d'Udekem, Christian P. Brizard, Igor E. Konstantinov
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2020)
Article
Cardiac & Cardiovascular Systems
Paolo D'Ambrosio, Derek Tran, Charlotte E. Verrall, Chantal Attard, Maria Fiatarone Singh, Julian Ayer, Yves d'Udekem, Stephen Twigg, David S. Celermajer, Rachael Cordina
CONGENITAL HEART DISEASE
(2019)
Article
Cardiac & Cardiovascular Systems
Michael Daley, Karin du Plessis, Dianna Zannino, Tim Hornung, Patrick Disney, Rachael Cordina, Leeanne Grigg, Dorothy J. Radford, Andrew Bullock, Yves d'Udekem
Article
Cardiac & Cardiovascular Systems
Tarek Alsaied, Rahul H. Rathod, Jamil A. Aboulhosn, Werner Budts, Jeffrey B. Anderson, Helmut Baumgartner, David W. Brown, Rachael Cordina, Yves D'udekem, Salil Ginde, David J. Goldberg, Bryan H. Goldstein, Adam M. Lubert, Erwin Oechslin, Alexander R. Opotowsky, Jack Rychik, Kurt R. Schumacher, Anne Marie Valente, Gail Wright, Gruschen R. Veldtman
Summary: This study reached a consensus among experts using the Delphi methodology to establish unified definitions for morbidities seen after the Fontan palliation, aiming to standardize research and clinical practices in this field.
Article
Cardiac & Cardiovascular Systems
Yaroslav Ivanov, Edward Buratto, Phillip Naimo, Adrienne Lui, Thomas Hu, Yves D'Udekem, Christian P. Brizard, Igor E. Konstantinov
Summary: The incidence of LVOTO after AVSD repair is low, but the recurrence rate is high. Standard subaortic resection does not always provide definitive relief for LVOTO. Survival after LVOTO reoperation is excellent.
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Alyssia Venna, Yves d'Udekem
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Soichiro Henmi, Yasin Essa, Mahmut Ozturk, Aybala Tongut, Manan Desai, Can Yerebakan, Yves d'Udekem
Summary: This study retrospectively evaluated the outcomes of cardiovascular surgery in very low birth weight patients. The study found that the occurrence of postoperative intracerebral hemorrhage was significantly higher in low birth weight patients compared to slightly higher weight patients. The early and late mortality rates were also higher in the low birth weight group. Early surgery was acceptable for simple lesions, while delayed surgery may provide better long-term outcomes for complex lesions.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)