The +37 kb Cebpa Enhancer Is Critical for Cebpa Myeloid Gene Expression and Contains Functional Sites that Bind SCL, GATA2, C/EBPα, PU.1, and Additional Ets Factors

C/EBPα in normal and malignant myelopoiesis

(2015) Alan D. Friedman   INTERNATIONAL JOURNAL OF HEMATOLOGY

The Cebpa +37-kb enhancer directs transgene expression to myeloid progenitors and to long-term hematopoietic stem cells

(2014) Hong Guo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

An atlas of active enhancers across human cell types and tissues

(2014) Robin Andersson et al.   NATURE

CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing

(2014) Tessa G. Montague et al.   NUCLEIC ACIDS RESEARCH

Granulopoiesis Requires Increased C/EBPα Compared to Monopoiesis, Correlated with Elevated Cebpa in Immature G-CSF Receptor versus M-CSF Receptor Expressing Cells

(2014) Ou Ma et al.   PLoS One

C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis

(2014) Cailin Collins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin state dynamics during blood formation

(2014) D. Lara-Astiaso et al.   SCIENCE

C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors

(2014) Marie S. Hasemann et al.   PLoS Genetics

C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence

(2013) Min Ye et al.   NATURE CELL BIOLOGY

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis

(2012) H. Guo et al.   BLOOD

C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia

(2012) Meritxell Alberich-Jordà et al.   JOURNAL OF CLINICAL INVESTIGATION

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

(2012) A Ptasinska et al.   LEUKEMIA

Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb

(2011) Liang Zhao et al.   NUCLEIC ACIDS RESEARCH

Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators

(2010) Nicola K. Wilson et al.   Cell Stem Cell

Recombineering: a homologous recombination-based method of genetic engineering

(2009) Shyam K Sharan et al.   Nature Protocols