Article
Cardiac & Cardiovascular Systems
Fraser R. O. Wallace, Edward Buratto, Phillip S. Naimo, Johann Brink, Yves d'Udekem, Christian P. Brizard, Igor E. Konstantinov
Summary: The study evaluated the long-term outcomes of children undergoing aortic valve repair without patch material, finding that approximately one-third of children could achieve durable repair without patches. Infants and older children had lower reoperation rates, while neonates had higher reoperation rates.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Andreas Martinsson, Susanne J. Nielsen, Milan Milojevic, Bjorn Redfors, Elmir Omerovic, Theis Tonnessen, Tomas Gudbjartsson, Goran Dellgren, Anders Jeppsson
Summary: Surgical risk, age, and perceived life expectancy influence the choice between SAVR and transcatheter aortic valve implantation. This study aimed to determine median survival time in relation to surgical risk and chronological age in SAVR patients. The estimated survival is substantial following SAVR, especially in younger, low-risk patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Qiushi Ren, Juemin Yu, Tianyu Chen, Hailong Qiu, Erchao Ji, Tao Liu, Xiaowei Xu, Jianzheng Cen, Shusheng Wen, Jian Zhuang, Xiaobing Liu
Summary: This study reviewed the long-term outcomes of children who underwent aortic valve repair at a certain medical center and found that aortic valve repair remains a safe and durable solution for children with congenital aortic stenosis. Coexisting mitral stenosis, aortic valve anatomy, and certain surgical factors have been identified as risk factors for poor early and long-term outcomes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Aditya Sengupta, Rebecca Beroukhim, Christopher W. Baird, Pedro J. Del Nido, Tal Geva, Kimberlee Gauvreau, Edward Marcus, Stephen P. Sanders, Meena Nathan
Summary: This study compared the long-term outcomes of congenital aortic valve repair using porcine intestinal submucosa and autologous pericardium. The results showed that patients who received porcine intestinal submucosa had earlier reinterventions and more severe aortic regurgitation or stenosis during follow-up.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Johanna Schlein, Felix Wollmann, Alexandra Kaider, Dominik Wiedemann, Harald Gabriel, Stephan Hornykewycz, Eva Base, Ina Michel-Behnke, Guenther Laufer, Daniel Zimpfer
Summary: This study retrospectively analyzed the clinical data of 103 patients who underwent surgical repair for subvalvular aortic stenosis (SAS) over a period of 30 years. The results showed that surgical repair had good long-term efficacy for SAS, but the incidence of reoperations for SAS and aortic valve was still significant.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Flavien Vincent, Julien Ternacle, Tom Denimal, Mylene Shen, Bjorn Redfors, Cedric Delhaye, Matheus Simonato, Nicolas Debry, Basile Verdier, Bahira Shahim, Thibault Pamart, Hugues Spillemaeker, Guillaume Schurtz, Francois Pontana, Vinod H. Thourani, Philippe Pibarot, Eric Van Belle
Summary: TAVR is rapidly expanding its indications, but faces technical challenges and knowledge gaps when dealing with patients with bicuspid aortic valve (BAV). Physicians need to understand the BAV anatomy and TAVR procedure planning comprehensively to guide treatment decisions.
Article
Cardiac & Cardiovascular Systems
Maximiliaan L. Notenboom, Art Schuermans, Jonathan R. G. Etnel, Kevin M. Veen, Pieter C. van de Woestijne, Filip R. Rega, Willem A. Helbing, Ad J. J. C. Bogers, Johanna J. M. Takkenberg
Summary: This study aims to provide decision-making support for children undergoing aortic valve replacement (AVR) by reviewing published outcomes and estimating age-specific outcomes with different valve substitutes. The results show suboptimal outcomes in pediatric AVR, especially in young patients, with high mortality and reintervention risks.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Hirokazu Onishi, Masaki Izumo, Toru Ouchi, Haruhito Yuki, Toru Naganuma, Tatsuya Nakao, Sunao Nakamura
Summary: This retrospective study examined the clinical effects of aortic valve replacement (AVR) in patients with moderate mixed aortic valve disease (MAVD). The study found that approximately half of the patients eventually required AVR and patients who underwent AVR had a significantly lower rate of the primary endpoint compared to those managed with medical treatment.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Emilie Laflamme, Rachel M. Wald, S. Lucy Roche, Candice K. Silversides, Sara A. Thorne, Jack M. Colman, Lee Benson, Mark Osten, Eric Horlick, Erwin Oechslin, Rafael Alonso-Gonzalez
Summary: In a study of 215 patients with pulmonary valve stenosis (PVS) who underwent surgical valvotomy or balloon valvuloplasty, it was found that the majority of patients remained asymptomatic after a median follow-up of 38.6 years. Predictors of reinterventions and complications included RVOT intervention, presence of associated defects, and older age at the time of first repair.
Article
Cardiac & Cardiovascular Systems
Natalie Glaser, Veronica Jackson, Per Eriksson, Ulrik Sartipy, Anders Franco-Cereceda
Summary: The study aimed to analyze long-term survival in patients with Bicuspid Aortic Valve (BAV) who underwent aortic valve surgery. Results showed that the survival of BAV patients following surgery was excellent and similar to the general population, with slightly lower survival rates for women compared to men. These findings suggest that the timing of surgery according to current guidelines is appropriate and provide valuable information about the natural history of BAV in patients post-aortic valve surgery.
Article
Cardiac & Cardiovascular Systems
Takashi Kido, Alvise Guariento, Ilias P. Doulamis, Diego Porras, Christopher W. Baird, Pedro J. del Nido, Meena Nathan
Summary: The study identified a AoV annulus diameter Z score below -2.6 and a history of fetal BAV as significant predictive factors for AoV surgery after neonatal BAV. It was recommended to perform concomitant endocardial fibroelastosis resection during AoV surgery following neonatal BAV to improve left ventricular diastolic function.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Rheumatology
Oscar Plunde, Elisabet Svenungsson, Giulia Ferrannini, Anders Franco-Cereceda, Magnus Back
Summary: The study revealed that antiphospholipid antibodies (aPL) are more common in calcific aortic valve stenosis (CAVS) patients in the general population. The positivity of aPL was associated with altered aortic valve transcriptomics related to interferon pathways. Further research is needed to establish aPL as a possible risk marker and/or causal factor for CAVS and to explore new precision therapeutic targets.
Review
Cardiac & Cardiovascular Systems
Nazli Okumus, Sonu Abraham, Rishi Puri, W. H. Wilson Tang
Summary: This review comprehensively examines the phenotypes of AS in the context of HF progression and explores the evolving role of TAVR in specific populations.
JACC-HEART FAILURE
(2023)
Article
Acoustics
A. Tulzer, W. Arzt, G. Tulzer
Summary: This retrospective study analyzed fetuses with critical aortic stenosis and signs of hydrops who underwent fetal aortic valvuloplasty (FAV) in a center between 2000 and 2020. Results showed that in most fetuses with technically successful intervention, ventricular function improved, hydrops resolved, and 50% achieved a biventricular outcome.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Blanca Alcon, Pablo Martinez-Legazpi, Simon Stewart, Ana Gonzalez-Mansilla, Victor Cuadrado, Geoff Strange, Raquel Yotti, Enric Cascos, Antonia Delgado-Montero, Raquel Prieto-Arevalo, Teresa Mombiela, Elena Rodriguez-Gonzalez, M. Angeles Espinosa, Andrea Postigo, Enrique Gutierrez-Ibanes, Manuel Perez-Vallina, Francisco Fernandez-Aviles, David Playford, Javier Bermejo
Summary: This study investigated the relationship between the severity of aortic stenosis (AS) and cardiovascular events and mortality, and compared the predictive ability of different echocardiographic indices. The results showed a strong linear relationship between Vmax and all-cause mortality, cardiovascular events, and heart failure. However, there was a mismatch between the risks estimated based on Vmax and AVA indices in terms of outcomes.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)