Deficiency of Angulin-2/ILDR1, a Tricellular Tight Junction-Associated Membrane Protein, Causes Deafness with Cochlear Hair Cell Degeneration in Mice

A “Tric” to tighten cell-cell junctions in the cochlea for hearing

(2013) Tomohito Higashi et al.   JOURNAL OF CLINICAL INVESTIGATION

Tricellulin deficiency affects tight junction architecture and cochlear hair cells

(2013) Gowri Nayak et al.   JOURNAL OF CLINICAL INVESTIGATION

Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2 - tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis

(2012) T. Higashi et al.   JOURNAL OF CELL SCIENCE

Loss-of-Function Mutations of ILDR1 Cause Autosomal-Recessive Hearing Impairment DFNB42

(2011) Guntram Borck et al.   AMERICAN JOURNAL OF HUMAN GENETICS

LSR defines cell corners for tricellular tight junction formation in epithelial cells

(2011) S. Masuda et al.   JOURNAL OF CELL SCIENCE

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

(2011) Yoshiyuki Kawashima et al.   JOURNAL OF CLINICAL INVESTIGATION

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

Tight Junction–associated MARVEL Proteins MarvelD3, Tricellulin, and Occludin Have Distinct but Overlapping Functions

(2010) David R. Raleigh et al.   MOLECULAR BIOLOGY OF THE CELL

Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability

(2009) Susanne M. Krug et al.   MOLECULAR BIOLOGY OF THE CELL

Physiology and Function of the Tight Junction

(2009) J. M. Anderson et al.   Cold Spring Harbor Perspectives in Biology

A Claudin-9–Based Ion Permeability Barrier Is Essential for Hearing

(2009) Yoko Nakano et al.   PLoS Genetics

Knockout animals and natural mutations as experimental and diagnostic tool for studying tight junction functions in vivo

(2008) Mikio Furuse   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES