4.7 Letter

Vascular Formation of Nitrite After Exercise Is Abolished in Patients With Cardiovascular Risk Factors and Coronary Artery Disease

Journal

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Volume 55, Issue 14, Pages 1502-1503

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.jacc.2009.10.064

Keywords

-

Ask authors/readers for more resources

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Endocrinology & Metabolism

Physical Fitness and Cardiovascular Risk Factors in Novel Diabetes Subgroups

Nina Saatmann, Oana-Patricia Zaharia, Klaus Strassburger, Dominik Hans Pesta, Volker Burkart, Julia Szendroedi, Norbert Gerdes, Malte Kelm, Michael Roden

Summary: While endothelial function was similar across all groups, SIRD exhibited the lowest physical fitness. Interestingly, SAID showed the lowest cardiovascular risk within the first year after diabetes diagnosis compared to other diabetes subgroups.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Article Cardiac & Cardiovascular Systems

Flow-mediated dilation reference values for evaluation of endothelial function and cardiovascular health

Christian Heiss, Ana Rodriguez-Mateos, Mariam Bapir, Simon S. Skene, Helmut Sies, Malte Kelm

Summary: This study aims to assess Flow-Mediated Dilation (FMD) values in healthy individuals and provides reference values for cardiovascular health measurement. The study found that FMD values are inversely correlated with age, body mass index (BMI), glucose, cholesterol, and blood pressure. Individuals with higher FMD values are younger and have smaller brachial artery diameter, lower blood pressure and cholesterol. Comparisons with coronary artery disease (CAD) patients also showed that FMD values can be used to exclude cardiovascular disease and determine the health status. The meta-analysis results showed that the average FMD in healthy individuals is 6.4%, with a decline trend associated with age.

CARDIOVASCULAR RESEARCH (2023)

Article Cardiac & Cardiovascular Systems

Trends in direct oral anticoagulant (DOAC) prescribing in English primary care (2014-2019)

Mark Joy, John Williams, Subo Emanuel, Debasish Kar, Xuejuan Fan, Gayathri Delanerolle, Benjamin C. T. Field, Christian Heiss, Kevin G. Pollock, Belinda Sandler, Jasleen Arora, James P. Sheppard, Michael Feher, F. D. Richard Hobbs, Simon de Lusignan

Summary: This study aims to describe the trends in prescribing direct oral anticoagulants (DOACs) in primary care in England and assess the appropriate dose adjustment and adherence. The study found that the volume and quality of DOAC prescribing has increased yearly, but disparities in adherence exist.

HEART (2023)

Editorial Material Peripheral Vascular Disease

The year in vascular medicine: Highlights in Vasa - European Journal of Vascular Medicine 2022

Christian Heiss, Stefano Barco, Christian-Alexander Behrendt, Marianne Brodmann, Eva Freisinger, Sasan Partovi, Christos Rammos, Oliver J. Mueller

VASA-EUROPEAN JOURNAL OF VASCULAR MEDICINE (2023)

Article Peripheral Vascular Disease

Health effects of e-cigarettes and their use for smoking cessation from a vascular perspective A consensus statement of the German Society of Vascular Medicine endorsed by the European Society of Vascular Medicine

Bernd Krabbe, Christine Espinola-Klein, Nasser Malyar, Marianne Brodmann, Lucia Mazzolai, Jill J. F. Belch, Oliver J. Mueller, Christian Heiss

Summary: Tobacco consumption is a major risk factor for cardiovascular disease. Despite efforts to reduce smoking, the use of e-cigarettes is increasing, while tobacco smoking is decreasing. E-cigarettes are advertised as less harmful than regular cigarettes and helpful for quitting smoking, but they still pose risks and can cause vascular damage. Long-term health risks of e-cigarettes and their use by non-smokers as a first contact with nicotine are a concern. The controversy surrounding the use of e-cigarettes for smoking cessation is also discussed.

VASA-EUROPEAN JOURNAL OF VASCULAR MEDICINE (2023)

Article Multidisciplinary Sciences

Pilot study of optical coherence tomography angiography-derived microvascular metrics in hands and feet of healthy and diabetic people

Gavrielle R. Untracht, Nikolaos Dikaios, Abdullah K. Durrani, Mariam Bapir, Marinko V. Sarunic, David D. Sampson, Christian Heiss, Danuta M. Sampson

Summary: This pilot study evaluates OCTA-derived microvascular parameters in healthy individuals and patients with diabetes. It establishes reference values for different regions of the body and identifies potential biomarkers for diabetes.

SCIENTIFIC REPORTS (2023)

Article Medicine, General & Internal

Ankle Doppler for Cuffless Ankle Brachial Index Estimation and Peripheral Artery Disease Diagnosis Independent of Diabetes

Alexander D. Rodway, Darren Cheal, Charlotte Allan, Felipe Pazos-Casal, Lydia Hanna, Benjamin C. T. Field, Ajay Pankhania, Philip J. Aston, Simon S. Skene, Gary D. Maytham, Christian Heiss

Summary: Ankle brachial pressure index (ABPI) is a commonly used test for diagnosing peripheral artery disease (PAD), but its adoption in clinical practice is poor and its validity is limited, especially in diabetes. This study found that ABPI can be accurately estimated based on cuffless Doppler waveforms, and the estimated ABPI performs better than the standard ABPI in diagnosing PAD, regardless of the presence of diabetes.

JOURNAL OF CLINICAL MEDICINE (2023)

Editorial Material Cardiac & Cardiovascular Systems

Coronary Endarterectomy in Combination With Coronary Artery Bypass Grafting-Stepping Into the Light?

Tobias Zeus, Artur Lichtenberg, Malte Kelm

AMERICAN JOURNAL OF CARDIOLOGY (2023)

Article Peripheral Vascular Disease

Chronic PCSK9 inhibitor therapy leads to sustained improvements in endothelial function, arterial stiffness, and microvascular function

J. Schremmer, L. Busch, S. Baasen, Y. Heinen, R. Sansone, C. Heiss, M. Kelm, M. Stern

Summary: In this prospective trial, the effects of PCSK9i therapy on vascular parameters beyond its lipid lowering effect were investigated. The results showed that besides lowering LDL-C levels, PCSK9i therapy also improved endothelial function, reduced arterial stiffness, and improved microvascular function.

MICROVASCULAR RESEARCH (2023)

Article Biochemistry & Molecular Biology

Understanding the Impact of COVID-19 on Angioplasty Service and Outcome of Patients Treated for Chronic Limb-Threatening Ischaemia: A Single-Centre Retrospective Cohort Study

Alexander D. D. Rodway, Jenny Harris, Lydia Hanna, Charlotte Allan, Felipe Pazos Casal, Ciara Giltinan, Ali Dehghan-Nayeri, Andre Santos, Martin B. B. Whyte, Nikolaos Ntagiantas, Ivan Walton, Richard Brown, Simon S. S. Skene, Ajay Pankhania, Benjamin C. T. Field, Gary D. D. Maytham, Christian Heiss

Summary: The impact of COVID-19 restriction on lower-limb angioplasty service and outcome of CLTI patients in a UK secondary care setting was evaluated. The study found that the number of CLTI patients treated did not significantly change during COVID-19, but the proportion of day cases increased significantly. The 1-year major amputations increased and clinically driven target-lesion revascularization decreased during COVID-19. The 1-year mortality rate was significantly higher in hospitalized patients compared to day cases.

BIOMEDICINES (2023)

Editorial Material Cardiac & Cardiovascular Systems

Dynamic mitral regurgitation caused by exercise-induced left bundle branch abnormality and unmasked by isometric handgrip testing

Maximilian Spieker, Malte Kelm, Verena Veulemans

EUROPEAN HEART JOURNAL-CASE REPORTS (2023)

Article Biochemistry & Molecular Biology

Cocoa flavanol supplementation preserves early and late radial artery function after transradial catheterization

Michael Groene, Miriam Schillings, Dragos Duse, Nicolas Kramser, Christine Quast, Christian Heiss, Roberto Sansone, Christian Jung, Malte Kelm, Ralf Erkens

Summary: This study found that cocoa flavanols can prevent intimal hyperplasia and endothelial dysfunction after coronary angiography, opening up new possibilities for dietary interventions to mitigate vascular damage and thickening after mechanical injury.

FOOD & FUNCTION (2023)

Article Biochemistry & Molecular Biology

Cocoa flavanols improve peakVO(2) and exercise capacity in a randomized double blinded clinical trial in healthy elderly people

Michael Groene, Dragos Andrei Duse, Nicolas Kramser, Niklas Ophoff, Hendrik Schweers, Fabian Voss, Christine Quast, Roberto Sansone, Christian Heiss, Christian Jung, Malte Kelm, Ralf Erkens

Summary: This study investigated the effect of cocoa flavanols on cardiorespiratory fitness in healthy elderly people. The results showed that cocoa flavanols significantly improved aerobic exercise capacity, blood pressure, and vascular function. The conclusion is that cocoa flavanols have the potential to preserve cardiovascular health in the elderly.

FOOD & FUNCTION (2023)

Article Biochemistry & Molecular Biology

(Poly)phenol intake, plant-rich dietary patterns and cardiometabolic health: a cross-sectional study

Yong Li, Yifan Xu, Xuemei Ma, Melanie Le Sayec, Haonan Wu, Paola Dazzan, Chiara Nosarti, Christian Heiss, Rachel Gibson, Ana Rodriguez-Mateos

Summary: Diet is a modifiable risk factor for cardiometabolic diseases. Plant-rich dietary patterns and (poly)phenol intake are associated with reduced cardiometabolic risk. (Poly)phenols may mediate the beneficial effects of plant-rich diets.

FOOD & FUNCTION (2023)

No Data Available