Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug

Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1

(2014) Y. Wang et al.   CANCER RESEARCH

A meta-analysis of gene expression-based biomarkers predicting outcome after tamoxifen treatment in breast cancer

(2013) Zsuzsanna Mihály et al.   BREAST CANCER RESEARCH AND TREATMENT

Prognostic relevance of AIB1 (NCoA3) amplification and overexpression in breast cancer

(2013) E. Burandt et al.   BREAST CANCER RESEARCH AND TREATMENT

AIB1 predicts bladder cancer outcome and promotes bladder cancer cell proliferation through AKT and E2F1

(2013) Z-T Tong et al.   BRITISH JOURNAL OF CANCER

Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance

(2013) C Palmieri et al.   BRITISH JOURNAL OF CANCER

The Steroid Receptor Coactivator-3 Is Required for the Development of Castration-Resistant Prostate Cancer

(2013) Jean C-Y. Tien et al.   CANCER RESEARCH

Phase II Study of Bevacizumab in Combination with Sorafenib in Recurrent Glioblastoma (N0776): A North Central Cancer Treatment Group Trial

(2013) E. Galanis et al.   CLINICAL CANCER RESEARCH

FLT3 inhibitors for acute myeloid leukemia: a review of their efficacy and mechanisms of resistance

(2013) Michael R. Grunwald et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

BIBF 1120 (Nintedanib), a Triple Angiokinase Inhibitor, Induces Hypoxia but not EMT and Blocks Progression of Preclinical Models of Lung and Pancreatic Cancer

(2013) B. Kutluk Cenik et al.   MOLECULAR CANCER THERAPEUTICS

Pathological and molecular diagnosis of triple-negative breast cancer: a clinical perspective

(2012) F. Penault-Llorca et al.   ANNALS OF ONCOLOGY

Clinical and biologic features of triple-negative breast cancers in a large cohort of patients with long-term follow-up

(2012) L. Malorni et al.   BREAST CANCER RESEARCH AND TREATMENT

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome

(2012) M. T. Neary et al.   Disease Models & Mechanisms

Nuclear receptor coregulators: modulators of pathology and therapeutic targets

(2012) David M. Lonard et al.   Nature Reviews Endocrinology

Evaluation of tyrosine receptor kinases in the interactions of head and neck squamous cell carcinoma cells and fibroblasts

(2012) Larissa Sweeny et al.   ORAL ONCOLOGY

Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor  -Klotho

(2012) T. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Preclinical Evaluation of Minnelide as a Therapeutic Agent Against Pancreatic Cancer

(2012) R. Chugh et al.   Science Translational Medicine

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Small Molecule Inhibition of the Steroid Receptor Coactivators, SRC-3 and SRC-1

(2011) Ying Wang et al.   MOLECULAR ENDOCRINOLOGY

Does Surgery for Breast Cancer Induce Angiogenesis and Thus Promote Metastasis?

(2011) Youngjin Park et al.   ONCOLOGY

The Utility of the Small Rodent Electrocardiogram in Toxicology

(2011) Aimen K. Farraj et al.   TOXICOLOGICAL SCIENCES

Will newer tyrosine kinase inhibitors have an impact in AML?

(2010) Mark J. Levis   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Optical imaging predicts tumor response to anti-EGFR therapy

(2010) Emily E. Helman et al.   CANCER BIOLOGY & THERAPY

Steroid Receptor Coactivator-3 Expression in Lung Cancer and Its Role in the Regulation of Cancer Cell Survival and Proliferation

(2010) D. Cai et al.   CANCER RESEARCH

Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line

(2010) S. Karmakar et al.   ENDOCRINE-RELATED CANCER

SRC-3Δ4 Mediates the Interaction of EGFR with FAK to Promote Cell Migration

(2010) Weiwen Long et al.   MOLECULAR CELL

Triple-negative breast cancer: disease entity or title of convenience?

(2010) Lisa Carey et al.   Nature Reviews Clinical Oncology

Doxorubicin in Combination with a Small TGFβ Inhibitor: A Potential Novel Therapy for Metastatic Breast Cancer in Mouse Models

(2010) Abhik Bandyopadhyay et al.   PLoS One

AIB1 is a predictive factor for tamoxifen response in premenopausal women

(2009) S. Alkner et al.   ANNALS OF ONCOLOGY

AIB1 is required for the acquisition of epithelial growth factor receptor-mediated tamoxifen resistance in breast cancer cells

(2009) Wenhui Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pharmacogenetics of Breast Cancer: Toward the Individualization of Therapy

(2009) Jenny C. Chang et al.   CANCER INVESTIGATION

Surgical Stress Promotes Tumor Growth in Ovarian Carcinoma

(2009) J.-W. Lee et al.   CLINICAL CANCER RESEARCH

Triple negative breast cancer: current understanding of biology and treatment options

(2009) Soonmo Peter Kang et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Phase II trials of erlotinib or gefitinib in patients with recurrent meningioma

(2009) Andrew D. Norden et al.   JOURNAL OF NEURO-ONCOLOGY

Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts

(2009) C. L. Roland et al.   MOLECULAR CANCER THERAPEUTICS

Basal carcinoma of the breast revisited: an old entity with new interpretations

(2008) E Korsching et al.   JOURNAL OF CLINICAL PATHOLOGY

The AIB1 Oncogene Promotes Breast Cancer Metastasis by Activation of PEA3-Mediated Matrix Metalloproteinase 2 (MMP2) and MMP9 Expression

(2008) L. Qin et al.   MOLECULAR AND CELLULAR BIOLOGY

A phase I study of gefitinib, capecitabine, and celecoxib in patients with advanced solid tumors

(2008) E. T. Lam et al.   MOLECULAR CANCER THERAPEUTICS

Cardiac Glycosides as Novel Cancer Therapeutic Agents

(2008) R. A. Newman et al.   MOLECULAR INTERVENTIONS

Novel therapeutic applications of cardiac glycosides

(2008) Ioannis Prassas et al.   NATURE REVIEWS DRUG DISCOVERY

Role of AIB1 for Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Cells

(2008) Qingbo Su et al.   ONCOLOGY

SRC-3 Transcription-Coupled Activation, Degradation, and the Ubiquitin Clock: Is There Enough Coactivator to Go Around in Cells?

(2008) D. M. Lonard et al.   Science Signaling