Article
Cardiac & Cardiovascular Systems
Amgad Mentias, Marwan Saad, Milind Y. Desai, Amar Krishnaswamy, Venu Menon, Phillip A. Horwitz, Samir Kapadia, Mary Vaughan Sarrazin
Summary: The study compared outcomes of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with rheumatic aortic stenosis (AS), as well as TAVR in nonrheumatic AS. The results showed similar mortality rates between TAVR and SAVR for rheumatic AS patients, suggesting that TAVR could be a viable alternative to traditional surgery in this patient population.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Joscha Kandels, Michael Metze, Andreas Hagendorff, Stephan Stoebe
Summary: In patients with severe aortic stenosis and moderate aortic regurgitation, the transvalvular flow velocity and mean pressure gradient are significantly affected by the regurgitation, while the effective orifice area and the ratio between maximum velocity of the left ventricular outflow tract and transvalvular flow velocity are not. Borderline cases of aortic stenosis severity should be verified using geometric orifice area.
Article
Cardiac & Cardiovascular Systems
Jerry Ash, Gurmandeep S. Sandhu, Jose Arriola-Montenegro, Dzhalal Agakishiev, Marie-Annick Clavel, Philippe Pibarot, Sue Duval, Prabhjot S. Nijjar
Summary: This study investigated the usefulness of CT-derived aortic valve areas (AVAs) in determining the severity of aortic stenosis (AS). The results showed that CT-derived AVAs have poor discrimination for AS severity, and using an AVA(CT) <1.2-cm(2) threshold to define severe AS can lead to significant error. However, larger AVA(CT) thresholds improve specificity.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Branka Vulesevic, Naozumi Kubota, Ian G. Burwash, Claire Cimadevilla, Sarah Tubiana, Xavier Duval, Virginia Nguyen, Dimitri Arangalage, Kwan L. Chan, Erin E. Mulvihill, Luc Beauchesne, David Messika-Zeitoun
Summary: This study found that aortic valve area indexed to height may be more accurate in defining severe AS compared to the indexed to body surface area. The results suggest that AVA/H is better correlated with AVA than AVA/BSA and may provide a better predictive accuracy for severe AS.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Mai Iwataki, Yong-Jin Kim, Seung Woo Park, Lieng Hsi Ling, Cheuk-Man Yu, Hiroyuki Okura, Jong-Won Ha, Takeshi Hozumi, Hidekazu Tanaka, Chisato Izumi, Toshinori Yuasa, Jae-Kwan Song, Yutaka Otsuji, Dae-Won Sohn
Summary: The study found significant discrepancies between AVAI measured by Doppler and biplane methods, with greater discrepancies in patients with increased LV outflow tract flow velocity, shorter height, lower weight, older age, and smaller LV cavity dimensions. Combining AVAI values improved the predictive value for events.
CIRCULATION JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Renuka Jain, Tanvir Bajwa, Sarah Roemer, Hillary Huisheree, Suhail Q. Allaqaband, Stacie Kroboth, Ana Cristina Perez Moreno, A. Jamil Tajik, Bijoy K. Khandheria
Summary: By studying patients with severe aortic stenosis, it was found that the addition of mean aortic gradient to non-invasive systolic blood pressure can reliably assess myocardial work. Additionally, it was also discovered that GLS can improve post-TAVR in patients with severe aortic stenosis, while myocardial work reduces.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2021)
Review
Cardiac & Cardiovascular Systems
Ivana Okor, Tamunoinemi Bob-Manuel, Kiran Garikapati, Harith Baldawi, Connor Gillies, Uzoma N. Ibebuogu
Summary: Despite historical beliefs, recent case reports have shown successful transcatheter aortic valve replacement (TAVR) in patients with rheumatic aortic stenosis, even in the absence of significant leaflet calcification. This suggests the potential utility of TAVR in treating severe rheumatic aortic stenosis and warrants further investigation and consideration.
CURRENT PROBLEMS IN CARDIOLOGY
(2021)
Review
Medicine, General & Internal
Gloria Santangelo, Andrea Rossi, Filippo Toriello, Luigi Paolo Badano, David Messika Zeitoun, Pompilio Faggiano
Summary: Aortic stenosis is a common heart valve disease that often requires surgical or percutaneous intervention. Imaging plays a crucial role in diagnosis and guiding treatment decisions. Referral for aortic valve replacement is based on the severity of the condition and related symptoms.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Sergio Gamaza Chulian, Enrique Diaz Retamino, Rocio Carmona Garcia, Barbara Serrano Munoz, Javier Leon Jimenez, Soraya Gonzalez Estriegana, Jesus Oneto Otero
Summary: This study evaluated the prognostic value of aortic valve area (AVA) normalized to body size in patients with aortic stenosis. It found that an AVA/BSA < 0.50 cm²/m² was associated with significantly higher cardiovascular death risk, suggesting the potential use of 0.50 cm²/m² as a cutoff value to identify high-risk patients.
REVISTA ESPANOLA DE CARDIOLOGIA
(2021)
Article
Cardiac & Cardiovascular Systems
Nahoko Kato, Jeremy J. Thaden, William R. Miranda, Christopher G. Scott, Maurice E. Sarano, Kevin L. Greason, Patricia A. Pellikka
Summary: The study evaluated the impact of AVR on MR in patients with sAS, finding that MR improved in nearly 60% of patients after AVR, even in the majority of patients with organic MR. Various factors were associated with MR improvement, and post-operative improvement in organic MR was associated with better survival.
Article
Cardiac & Cardiovascular Systems
Nahoko Kato, Jeremy J. Thaden, William R. Miranda, Christopher G. Scott, Maurice E. Sarano, Kevin L. Greason, Patricia A. Pellikka
Summary: In patients with severe aortic stenosis (sAS) and mitral regurgitation (MR), about 60% of patients show improvement in MR after aortic valve replacement (AVR), even in the majority of patients with organic MR. Absence of atrial fibrillation in organic MR, iAVA <= 0.40 cm(2) in functional MR, and mitral annulus diameter < 3 cm and QRS duration < 115 ms in the overall population are associated with MR improvement. Lack of improvement in organic MR is associated with higher mortality.
Article
Cardiac & Cardiovascular Systems
Giovanni Benfari, Stefano Nistri, Federico Marin, Luca F. Cerrito, Luca Maritan, Elvin Tafciu, Ilaria Franzese, Francesco Onorati, Martina Setti, Michele Pighi, Andrea Rossi, Flavio L. Ribichini
Summary: The study found that the progression rate of aortic valve stenosis (AS) is an individual, almost unpredictable feature. Rapid progression is an incremental marker of excess mortality in asymptomatic patients with AS, independent of clinical and hemodynamic characteristics.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2021)
Article
Cardiac & Cardiovascular Systems
Ezequiel Guzzetti, Jin Kyung Oh, Mylene Shen, Marc R. Dweck, Kian Keong Poh, Amr E. Abbas, Ramy Mando, Gregg S. Pressman, Daniel Brito, Lionel Tastet, Tania Pawade, Mariano Luis Falconi, Diego Perez de Arenaza, William Kong, Edgar Tay, Philippe Pibarot, Jae-Kwan Song, Marie-Annick Clavel
Summary: This study aimed to validate the accuracy of sex-specific thresholds of aortic valve calcification (AVC) in Asians. The results showed that the AVC thresholds defining severe aortic stenosis (AS) were comparable between Asian and Caucasian populations, and similar to those proposed in the guidelines. However, the accuracy of AVC to identify severe AS, especially in Asian women, was sub-optimal. Therefore, the use of AVC-density is preferable in Asians.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Physiology
Eric Buffle, Athanasios Papadis, Christian Seiler, Stefano F. de Marchi
Summary: This study analyzed the relationship between flow and aortic valve opening area, finding that the aortic valve opening area reaches saturation as the stress tests increase in strength.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Review
Health Care Sciences & Services
Elke Boxhammer, Alexander E. Berezin, Vera Paar, Nina Bacher, Albert Topf, Sergii Pavlov, Uta C. Hoppe, Michael Lichtenauer
Summary: The current scientific data situation regarding cardiovascular biomarkers as non-invasive diagnostic tools for the determination of pulmonary hypertension in patients with severe aortic valve stenosis is poor. There is a great potential to combine different biomarkers in a non-invasive way to determine the presence or absence of pulmonary hypertension.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
