Article
Chemistry, Multidisciplinary
Emma N. Cook, Diane A. Dickie, Charles W. Machan
Summary: This study presents a bioinspired non-heme Fe complex with a tripodal [N3O](-) ligand framework that shows electrocatalytic activity towards dioxygen reduction using acetic acid as a proton source. The complex selectively produces water via a 2+2 mechanism, with H2O2 generated as an intermediate species, and spectroscopic analysis reveals the formation of an Fe(III)-hydroxide species following exposure to H2O2. The ligand's carboxylate moiety is shown to be sensitive to hydrogen-bonding interactions with the acetic acid proton donor during reduction, providing insight into the distribution of charge and proton donors in mononuclear non-heme Fe active sites during reactions with dioxygen.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Inorganic & Nuclear
Chuan-Kuei Chiang, Yu-Chiao Liu, Kai-Ti Chu, Jing-Ting Chen, Cheng-Yeh Tsai, Gene-Hsiang Lee, Ming-Hsi Chiang, Chien-Ming Lee
Summary: In this study, a dimeric and mononuclear Fe-NO model complex were synthesized and characterized, showing the formation of a thiolate-bridged bimetallic complex during the reduction of the mononuclear complex. The electronic structure of the bimetallic complex was described as a FeII/{Fe(NO)2}9 state, providing insights into the NO scrambling behavior in the activity of flavodiiron nitric oxide reductases (FNORs).
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Aniruddha Dey, Jesse B. Gordon, Therese Albert, Sinan Sabuncu, Maxime A. Siegler, Samantha N. MacMillan, Kyle M. Lancaster, Pierre Moenne-Loccoz, David P. Goldberg
Summary: A new nonheme iron(II) complex was reported, which reacts with NO(g) to form a stable mononitrosyl complex. The mononitrosyl complex exhibits highly activated characteristics and can rapidly convert to N2O in the absence of an exogenous reductant.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Physical
Rimsha Mehmood, Vyshnavi Vennelakanti, Heather J. Kulik
Summary: Researchers investigate substrate/active-site dynamics of nonheme iron halogenases like BesD and WelO5 using experimental and computational methods, revealing the importance of active-site configurational isomerization for selective halogenation in WelO5. They also find distinct patterns of substrate-protein interactions for these enzymes, and discuss how optimal substrate/active-site geometry plays a crucial role in facilitating chemoselectivity in halogenases. Their work demonstrates different substrate-dependent strategies used to promote selectivity in halogenases.
Article
Chemistry, Physical
Christopher J. Miller, Yingyue Chang, Christina Wegeberg, Christine J. McKenzie, T. David Waite
Summary: This study demonstrates that the activation of [Fe-III(OH)(tpena)](+) by H2O2 proceeds by the formation of [Fe-III(OOH)(tpena)](+), which undergoes two major reactions to produce HO· and [Fe-IV(O)(tpena)](+). The production of HO· was quantified by a chemiluminescence method, showing that [Fe-IV(O)(tpena)](+) is produced in much larger yields than HO·. Additionally, the study indicates that a reactive high-valent iron-oxo species and HO· can be generated under mild, aqueous ambient conditions, which represents a significant contribution to biomimetic nonheme chemistry in water.
Article
Chemistry, Multidisciplinary
Juan A. Valdez-Moreira, Daniel M. Beagan, Hao Yang, Joshua Telser, Brian M. Hoffman, Maren Pink, Veronica Carta, Jeremy M. Smith
Summary: The study characterized a thermally stable iron(III) oxo complex and analyzed its structure, spectroscopic, and computational properties. The complex has an unusually short iron-oxygen bond length and is able to perform hydrocarbon oxidations.
ACS CENTRAL SCIENCE
(2021)
Article
Multidisciplinary Sciences
Yun Ji Park, Richard J. Jodts, Jeffrey W. Slater, Reyvin M. Reyes, Valerie J. Winton, Rana A. Montaser, Paul M. Thomas, William B. Dowdle, Anahi Ruiz, Neil L. Kelleher, J. Martin Bollinger, Carsten Krebs, Brian M. Hoffman, Amy C. Rosenzweig
Summary: The iron-containing heterodimeric MbnBC enzyme complex plays a central role in the biosynthesis of methanobactins (Mbns) and its active species is a mixed-valent, antiferromagnetically coupled Fe(II)Fe(III) center. MbnC is also involved in recognition of the MbnA leader peptide.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Engineering, Environmental
Mingyue Liu, Zhiyuan Feng, Xinmiao Luan, Wenhai Chu, Hongying Zhao, Guohua Zhao
Summary: This study successfully accelerated the regeneration of Fe2+ in the electro-Fenton (EF) process by using nitrogen-doped carbon aerogel (NDCA) as a reducing agent, resulting in a higher production of hydroxyl radicals and efficient removal of various pollutants, including organic compounds and ammonia nitrogen.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Samantha Carter, Wenjie Tao, Rajat Majumder, Alexander Yu. Sokolov, Shiyu Zhang
Summary: We investigate the spin switching behavior of dicopperoxo nitrosyl [Cu-2(O)(NO)](2+) complexes at different temperatures and its influence on hydrogen atom transfer (HAT) reactivity. Our findings indicate that the HAT reaction is predominantly mediated by the S = 1/2 isomer of [Cu-2(O)(NO)](2+) complexes at low temperatures (198 K). Moreover, the introduction of functional groups that create an unsymmetric secondary coordination environment enhances the HAT rates by perturbing the spin equilibria. These findings suggest that metalloenzymes in natural proteins may employ similar strategies to control HAT reactions due to their often unsymmetric coordination environments.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Jing Xiang, Min Peng, Yi Pan, Li-Juan Luo, Shun-Cheung Cheng, Xin-Xin Jin, Shek-Man Yiu, Wai-Lun Man, Chi-Chiu Ko, Kai-Chung Lau, Tai-Chu Lau
Summary: The study presented the first example of N-dealkylation of various alkylamines by a luminescent osmium(VI) nitrido complex induced by visible light.
Article
Chemistry, Inorganic & Nuclear
Emma N. Cook, Shelby L. Hooe, Diane A. Dickie, Charles W. Machan
Summary: A new terpyridine-based FeN3O catalyst, Fe-(tpy(tbu)pho)Cl-2, is reported for reducing O2 to H2O. Mechanistic studies suggest a 2 + 2 mechanism with hydrogen peroxide produced as an intermediate in the reduction process.
INORGANIC CHEMISTRY
(2022)
Article
Green & Sustainable Science & Technology
Wen Ni, Yilong Ji, Linbin Liang, Bo Ding, Xiazhang Li, Huihong Lu
Summary: This study proposes a new method for the fabrication of perovskite-based SCR catalysts, which shows enhanced activity and NO removal efficiency by doping with lanthanides and transition elements. Additionally, the adsorption property of NO in the perovskite with the ABO(3) formula can be tuned by the electron occupancy of the parentage orbitals.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Chemistry, Multidisciplinary
Chang-Chih Hsieh, Cheng-Yao Li, Ming-Hsi Chiang, Yih-Chern Horng
Summary: In this study, a catalytic intramolecular N-S bond formation method for synthesizing BIT compounds was reported. The method involved the use of an Fe(III) dithiolate catalyst and easily prepared disulfide precursors activated by O-2. Interestingly, substituting O-2 with the milder O-donor oxidant ONMe3 enhanced the catalytic performance.
CHEMICAL COMMUNICATIONS
(2022)
Article
Engineering, Environmental
Qiming Tang, Kevin Huang
Summary: Green Steel is a new technology that uses renewable derived Green Hydrogen to produce steel and achieve zero carbon emissions. This study investigates the kinetics of iron ore reduction and finds that the one-step reduction reactions follow the Johnson-Mehl-Avrami phase transformation model.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Environmental
Ting Zhou, Yan Huang
Summary: This study investigated the performance and kinetics of Fe(III)EDTA and Fe(II)EDTA-NO reduction by different supported (nano)ZVI, and their coupling with NO removal and Fe(II)EDTA regeneration. Activated carbon-supported nano-ZVI showed the highest efficiency and N-2 selectivity for the reduction of Fe(III)EDTA and Fe(II)EDTA-NO.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Chemistry, Applied
Ehab M. H. Abdelraheem, Sayed M. Hassan, Mohamed M. H. Arief, Somaia G. Mohammad
Article
Chemistry, Inorganic & Nuclear
Melody A. Rhine, Brian C. Sanders, Ashis K. Patra, Todd C. Harrop
INORGANIC CHEMISTRY
(2015)
Article
Environmental Sciences
Anne Marie Zimeri, Sara Wagner Robb, Sayed M. Hassan, Rupali R. Hire, Melissa B. Davis
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2015)
Article
Engineering, Environmental
R. Henderson, N. Kabengi, N. Mantripragada, M. Cabrera, S. Hassan, A. Thompson
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2012)
Article
Biochemistry & Molecular Biology
Brian C. Sanders, Ashis K. Patra, Todd C. Harrop
JOURNAL OF INORGANIC BIOCHEMISTRY
(2013)
Article
Soil Science
Jake Mowrer, David E. Kissel, Miguel Cabrera, Sayed M. Hassan
SOIL SCIENCE SOCIETY OF AMERICA JOURNAL
(2013)
Article
Soil Science
Jake Mowrer, David Kissel, Miguel Cabrera, Sayed Hassan
SOIL SCIENCE SOCIETY OF AMERICA JOURNAL
(2014)
Article
Chemistry, Multidisciplinary
Ashis K. Patra, Koustubh S. Dube, Brian C. Sanders, Georgia C. Papaefthymiou, Jeanet Conradie, Abhik Ghosh, Todd C. Harrop
Article
Chemistry, Physical
Mette L. H. Sorensen, Brian C. Sanders, L. Perry Hicks, Maria H. Rasmussen, Andreas L. Vishart, Jacob Kongsted, Jay R. Winkler, Harry B. Gray, Thorsten Hansen
JOURNAL OF PHYSICAL CHEMISTRY B
(2020)
Article
Biology
Connor J. Cooper, Kaiyuan Zheng, Katherine W. Rush, Alexander Johs, Brian C. Sanders, Georgios A. Pavlopoulos, Nikos C. Kyrpides, Mircea Podar, Sergey Ovchinnikov, Stephen W. Ragsdale, Jerry M. Parks
COMMUNICATIONS BIOLOGY
(2020)
Article
Chemistry, Inorganic & Nuclear
Danh X. Ngo, Sarah A. Del Ciello, Brendon J. McNicholas, Brian C. Sanders, Javier Fajardo, Harry B. Gray, Jay R. Winkler
Article
Multidisciplinary Sciences
Chunliu Zhuo, Xin Wang, Maite Docampo-Palacios, Brian C. Sanders, Nancy L. Engle, Timothy J. Tschaplinski, John Hendry, Costas D. Maranas, Fang Chen, Richard A. Dixon
Summary: The factors controlling the composition of lignin are still unknown. C-lignin, a homopolymer of caffeyl alcohol, has unique properties as a biomaterial and a precursor of industrial chemicals. In the seed coat of Cleome hassleriana, lignin switches from guaiacyl (G)- to C-lignin at around 12 to 14 days after pollination, which is associated with changes in the monolignol pathway.
Article
Multidisciplinary Sciences
Brian C. Sanders, Suman Pokhrel, Audrey D. Labbe, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Hugh O'Neill, Manat Kaur, Jurgen G. Schmidt, Walter Reichard, Surekha Surendranathan, Jyothi Parvathareddy, Lexi Phillips, Christopher Rainville, David E. Sterner, Desigan Kumaran, Babak Andi, Gyorgy Babnigg, Nigel W. Moriarty, Paul D. Adams, Andrzej Joachimiak, Brett L. Hurst, Suresh Kumar, Tauseef R. Butt, Colleen B. Jonsson, Lori Ferrins, Soichi Wakatsuki, Stephanie Galanie, Martha S. Head, Jerry M. Parks
Summary: Designed a series of protease inhibitors targeting SARS-CoV-2, with the most effective inhibitor capable of blocking viral replication in mammalian cells and showing no significant inhibition of human proteases. These findings present an opportunity for the development of protease inhibitors.
NATURE COMMUNICATIONS
(2023)
