Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 135, Issue 36, Pages 13294-13297Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja406653n
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- KAKENHI
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A method for asymmetric alpha-arylation of amino acid derivatives has been developed. The arylation was performed by Clayden rearrangement of ester enolates via memory of chirality to give hydantoins with an arylsubstituted tetrasubstituted carbon with up to 99% ee.
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