Article
Multidisciplinary Sciences
Rengan Luo, Haifeng Lv, Qiaobo Liao, Ningning Wang, Jiarui Yang, Yang Li, Kai Xi, Xiaojun Wu, Huangxian Ju, Jianping Lei
Summary: This study demonstrates the efficient ECL emitter using a D-A COF with adjustable intrareticular charge transfer, leading to a significant enhancement in ECL intensity. The dual-peaked ECL patterns of COFs are achieved through an IRCT mediated competitive oxidation mechanism, providing new insights for designing next-generation ECL devices.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Zhuangzhuang Ru, Yue Jia, Yu Du, Yujie Han, Nuo Zhang, Xiang Ren, Qin Wei
Summary: Developing a convenient assay method is crucial for clinical treatment due to the low abundance of bleomycin. This study proposes an electrochemiluminescence biosensor using zirconium-based metal-organic frameworks for sensitive detection of bleomycin. The use of a long guanine-rich single-stranded DNA and the auxiliary role of exonuclease III enhance the electrochemiluminescence efficiency. The negative correlation between electrochemiluminescence intensity and bleomycin concentration enables the accurate detection of bleomycin in the range from 5.0 nM to 50 μM, with a limit of detection of 0.50 nM.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Yujie Liu, Hongding Zhang, Binxiao Li, Jianwei Liu, Dechen Jiang, Baohong Liu, Neso Sojic
Summary: This study successfully imaged single biomolecules using RuDSNs/AuNPs as ECL nanoemitters, demonstrating the visualization of single protein molecules and single membrane proteins in cells, overcoming the challenges in ultrasensitive ECL analysis and providing valuable information for cellular biology research.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Analytical
Jie-Kang Tian, Mei-Ling Zhao, Yu-Meng Song, Xia Zhong, Ruo Yuan, Ying Zhuo
Summary: A new field-free and highly ordered spherical nucleic acid (SNA) nanostructure was self-assembled using ferrocene-labeled DNA tweezers and DNA linkers, serving as an ECL switch for improved recognition efficiency. Combined with mesoporous silica nanospheres (mSiO(2) NSs) filled with Rub-Pt nanoparticles (Rub-Pt@mSiO(2) NSs), a highly sensitive detection platform for let-7b microRNA was achieved through target-triggered SNA deconstruction, highlighting potential applications in biomarker analyses.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Lirong Jiang, Mengmeng Jing, Bing Yin, Wenjun Du, Xiaojian Wang, Ying Liu, Shuang Chen, Manzhou Zhu
Summary: Metal nanoclusters are used as electrochemiluminescent luminophores due to their electrochemical and optical properties. In this study, chiral Au9Ag4 metal nanocluster enantiomers were integrated with optical activity and electrochemiluminescence, resulting in circularly polarized electrochemiluminescence. The enantiomers exhibited chirality and bright-red emission, and showed mirror-imaged CPECL signals at 805 nm. The nanocluster CPECL platform can be used for chiral discrimination and local chirality detection with high sensitivity and contrast.
Article
Chemistry, Applied
Kiun Cheong, Seung Chan Kim, Jun Yeob Lee
Summary: This study explores the potential of using o-carborane as a new acceptor in designing donor-acceptor (D-A) type thermally activated delayed fluorescence (TADF) materials. The designed D-A type TADF emitter exhibits deep red emission as proven by delayed fluorescence and electroluminescence analysis. The maximum external quantum efficiency of the devices is found to be 5.2% in the doped device and 2.1% in the non-doped device.
Article
Chemistry, Multidisciplinary
Kyoung-Rok Kim, Jiwoo Kim, Jinrok Oh, Joohoon Kim, Jong-In Hong
Summary: Donor-acceptor (D-A) type molecules with a skeleton consisting of a dimethylaminonaphthalene donor and an oxazaborine acceptor were designed as efficient electrochemiluminescence (ECL) luminophores with tunable intramolecular charge transfer (ICT). The experimental and computational results demonstrated that the ICT characteristics play a critical role in the electrochemistry and ECL of luminophores in the presence of tri-n-propylamine. Furthermore, the dual-peaked ECL-potential behaviors of the luminophores were rationalized using two competitive pathway ECL mechanisms, elucidated through the use of spooling ECL spectroscopy.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Siqi Yu, Xiangfu Hu, Jianbin Pan, Jianping Lei, Huangxian Ju
Summary: In this study, a novel confinement system was proposed for the self-enhanced electrochemiluminescence (ECL) by codoping ECL emitter and coreactant in silica nanoparticles. The obtained nanoparticles showed stronger ECL emission and were used for the monitoring of glycoprotein on living cell membranes.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Rui Zhang, Xuan He, Jia-Min Jiang, Pan-Pan Li, Hai-Yan Wang, Lin Li, Jia-Xiang Yang, Lin Kong
Summary: TD-DFT quantum calculation was performed to predict the electronic transition and absorption/emission maxima of pyrrole-difluoroboron derivatives with different electron donor-acceptor units or conjugated degrees. It led to the design of a new NIR fluorophore TPBD-BP, which showed excellent water solubility, biocompatibility, and AIE for in vivo imaging. The NIR-II emission signal of TPBD-BP dots could be observed in the reproductive organs of normal nude mice, indicating potential applications in biological imaging.
BIOORGANIC CHEMISTRY
(2021)
Article
Chemistry, Analytical
Jaeyoon Kim, Kyunglim Pyo, Dongil Lee, Won-Yong Lee
Summary: This study characterized the ECL behavior of atomically precise Au-22(SG)(18) NCs in aqueous solution and found that their ECL intensity was significantly higher than that of commonly used Au@BSA NCs, showing sensitivity to the concentrations of Au-22(SG)(18) NCs and TPA.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Virendra Kumar, Simran Sony, Navpreet Kaur, Shaikh M. M. Mobin, Paramjit Kaur, Kamaljit Singh
Summary: This article reports the photophysical properties of a new multifunctional molecular probe, PYTZ-P, which shows modulated emission behavior in response to external stimuli and exhibits high sensitivity towards protons and Hg2+ ions, suggesting its potential applications in bioimaging.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Alessandra Zanut, Marianna Rossetti, Massimo Marcaccio, Francesco Ricci, Francesco Paolucci, Alessandro Porchetta, Giovanni Valenti
Summary: In this study, we investigated the mechanism of ECL signal generation at the nanoscale using DNA nanoswitches with different stem stabilities. By tuning the stability of the DNA nanoswitches, we were able to activate different ECL mechanisms, achieve a digital-like association curve, and increase signal gain significantly while maintaining low detection limits. Our findings demonstrate the potential for designing customized DNA devices for highly efficient dual-signal-output ratiometric-like ECL systems.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Hongying Jia, Lei Yang, Xue Dong, Limin Zhou, Qin Wei, Huangxian Ju
Summary: This study proposed a strategy to improve the ECL performance of Au nanoclusters by introducing L-Cys, which limits the intramolecular motion and nonradiative relaxation of the excited state. Triethylamine was used as a coreactant to further enhance the ECL performance.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Yi-Hui He, Feng-Ming Xie, Kai Zhang, Dezhi Yang, Yang Shen, Hao-Ze Li, Dongge Ma, Yan-Qing Li, Jian-Xin Tang
Summary: Rod-like orange-red TADF emitters of 2BNCz-PZ and 2BNtCz-PZ with A-D-A configuration are developed, achieving highly efficient emission. The optimized orange-red OLED based on 2BNtCz-PZ exhibits a maximum EQE of 31.0% and a slight EQE roll-off to 22.2% at 1 000 cd m(-2) with emission peak over 600 nm.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Multidisciplinary Sciences
Siqi Yu, Yu Du, Xianghong Niu, Guangming Li, Da Zhu, Qian Yu, Guizheng Zou, Huangxian Ju
Summary: By modifying black phosphorus quantum dots with arginine, the excited states can be modulated and the electrochemiluminescence efficiency can be enhanced, providing a new signal tag for conveniently evaluating the inhibiting efficiency of cell surface integrin.
NATURE COMMUNICATIONS
(2022)