Monoclonal Antibodies Targeting the Alpha-Exosite of Botulinum Neurotoxin Serotype/A Inhibit Catalytic Activity

Functional Characterization of Botulinum Neurotoxin Serotype H as a Hybrid of Known Serotypes F and A (BoNT F/A)

(2015) Suzanne R. Kalb et al.   ANALYTICAL CHEMISTRY

Cargo-Delivery Platforms for Targeted Delivery of Inhibitor Cargos Against Botulism

(2014) Brenda Wilson et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Structural insight into exosite binding and discovery of novel exosite inhibitors of botulinum neurotoxin serotype A through in silico screening

(2014) Xin Hu et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library

(2014) Sebastian Miethe et al.   mAbs

Molecular Characterization of a Novel Botulinum Neurotoxin Type H Gene

(2013) Nir Dover et al.   JOURNAL OF INFECTIOUS DISEASES

A Novel Strain of Clostridium botulinum That Produces Type B and Type H Botulinum Toxins

(2013) Jason R. Barash et al.   JOURNAL OF INFECTIOUS DISEASES

Targeted delivery into motor nerve terminals of inhibitors for SNARE-cleaving proteases via liposomes coupled to an atoxic botulinum neurotoxin

(2012) Om P. Edupuganti et al.   FEBS Journal

Glycine insertion at protease cleavage site of SNAP25 resists cleavage but enhances affinity for botulinum neurotoxin serotype A

(2011) Mengfei Ho et al.   PROTEIN SCIENCE

A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic α-Exosite Binding Region

(2010) Jianbo Dong et al.   JOURNAL OF MOLECULAR BIOLOGY

Recombinant botulinum neurotoxin A heavy chain-based delivery vehicles for neuronal cell targeting

(2010) M. Ho et al.   PROTEIN ENGINEERING DESIGN & SELECTION

An Exosite-Specific ssDNA Aptamer Inhibits the Anticoagulant Functions of Activated Protein C and Enhances Inhibition by Protein C Inhibitor

(2009) Jens Müller et al.   CHEMISTRY & BIOLOGY

Bimodal modulation of the botulinum neurotoxin protein-conducting channel

(2009) A. Fischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tandem fluorescent proteins as enhanced FRET-based substrates for botulinum neurotoxin activity

(2009) Melissa Pires-Alves et al.   TOXICON

Localization of the sites and characterization of the mechanisms by which anti-light chain antibodies neutralize the actions of the botulinum holotoxin

(2009) Tsuyoshi Takahashi et al.   VACCINE

Neutralization of Botulinum Neurotoxin by a Human Monoclonal Antibody Specific for the Catalytic Light Chain

(2008) Sharad P. Adekar et al.   PLoS One

Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction

(2008) Pål Stenmark et al.   PLoS Pathogens