Article
Chemistry, Organic
Miaomiao Liu, Xiaotao Zhang, Rongrong Bao, Fangtao Xiao, Shouyi Cen, Zhipeng Zhang
Summary: An axially chiral N,N-ligand derived from a BINOL-based skeleton and phenanthroline is found to promote Pd-catalyzed asymmetric allylic amination and alkylation of allyl acetates. The reaction is compatible with various amine substrates and affords chiral products with high yield and enantiomeric excess.
Article
Chemistry, Organic
Yu Hao, Zi-Hao Li, Peng-Fei Lian, Quan-Zhe Li, Yuan She, Zhi-Gang Ma, Shu-Yu Zhang
Summary: This study describes a stereoselective sulfa-Michael/aldol cyclization reaction using a novel axially chiral styrene-based organocatalyst. The reaction successfully produces highly substituted tetrahydrothiophenes with an alkyne-substituted quaternary stereogenic center. The reaction tolerates a wide range of alkynyl-substituted acrylamides and shows excellent asymmetric introduction, scalability, and product diversification.
Article
Chemistry, Physical
Elizabeth Florez, Nancy Acelas, Sara Gomez, Cacier Hadad, Albeiro Restrepo
Summary: This work provides a detailed analysis of the thermodynamic factors and intermolecular interactions that stabilize (water)(20) cavities and methane clathrate. The study reveals a complex interplay between entropy and enthalpy contributions, and highlights the role of non-covalent interactions in stabilizing the CH4@5(12) clathrate.
Article
Chemistry, Medicinal
Senel Teke Tuncel, Ilke Demir, Safiye Sag Erdem, Ilknur Dogan
Summary: In this study, a series of 3-(pyridin-2-yl)-2-(pyridin-2-ylimino)thiazolidin-4-ol derivatives were synthesized regioselectively using LiAlH4 at room temperature. The formation of M/P isomers was observed due to the restricted rotation around the N3-C-aryl single bond. Computational DFT study demonstrated that the OH group of the hemiaminal formed an intramolecular hydrogen bond with the pyridyl nitrogen during this restricted rotation, which presumably inhibited dehydration and stabilized the molecule.
Article
Chemistry, Medicinal
Takuya Murai, Shohei Hamada, Yusuke Kobayashi, Takahiro Sasamori, Takumi Furuta
Summary: The preparation, optical resolution, and structural investigations of a series of axially chiral biaryl dicarboxylic acids bearing oxygen, sulfur, and selenium atoms were conducted. The study revealed that the conformational control of these compounds can be achieved through chalcogen bonding interactions and tetrel bonding interactions. The physical and chiroptical properties of these biaryl dicarboxylic acids were also explored.
CHEMICAL & PHARMACEUTICAL BULLETIN
(2022)
Article
Chemistry, Inorganic & Nuclear
Hui Liu, Yue-Wen Mu, Si-Dian Li
Summary: The possible existence of novel aromatic members of the borospherene family, C-2 B-38(+) (1/1 ') and C-2 B-38(2+) (3/3 '), with unique structure and bonding properties, are predicted in this study. Molecular dynamics simulations indicate that both cluster cations are dynamically stable at high temperatures. Computational simulations of IR, Raman, and UV-vis spectra of these cluster cations are provided to facilitate future spectral characterizations.
JOURNAL OF CLUSTER SCIENCE
(2022)
Article
Chemistry, Organic
Sapna Ahuja, Steffen Jockusch, Angel Ugrinov, Jayaraman Sivaguru
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Engineering, Environmental
Marina Arino Martin, Jayaraman Sivaguru, John McEvoy, Prinpida Sonthiphand, Andre Delorme, Eakalak Khan
Biographical-Item
Chemistry, Physical
Jayaraman Sivaguru
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Sunil Kumar Kandappa, Lakshmy Kannadi Valloli, Steffen Jockusch, Jayaraman Sivaguru
Summary: An unprecedented photochemical reactivity of 1,3-dicarbonyl compounds with amino-alkenes has been discovered, leading to the formation of dihydropyrans. This novel reaction has changed the established paradigm related to the De Mayo reaction between 1,3-dicarbonyl compounds and alkenes and allows for convenient access to the Marmycin core from commercially available reactants in a single step. Detailed origin and scope of this new photoreaction have been investigated with preliminary photophysical and mechanistic studies.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Environmental Sciences
Marina Arino Martin, Jayaraman Sivaguru, John McEvoy, Prinpida Sonthiphand, Eakalak Khan
Summary: Endoxifen, the main metabolite of tamoxifen, was found in municipal wastewater treatment plants. Exposure to sunlight led to generation of phototransformation by-products (PBPs) which were more toxic to aquatic life than the original compound. Further research is needed on the presence and impact of these PBPs in surface water near discharge points.
ENVIRONMENTAL RESEARCH
(2021)
Article
Chemistry, Physical
Ashish Sharma, Stavros Athanasopoulos, Elango Kumarasamy, Chanakarn Phansa, Amir Asadpoordarvish, Randy P. Sabatini, Raj Pandya, Kaia R. Parenti, Samuel N. Sanders, Dane R. McCamey, Luis M. Campos, Akshay Rao, Murad J. Y. Tayebjee, Girish Lakhwani
Summary: By designing a compound containing an axially chiral binaphthyl bridge and utilizing its chiroptical response as a marker for intra-molecular singlet fission chromophore-bridge-chromophore interactions, the study demonstrates the promising application of chiroptical techniques in investigating these interactions.
JOURNAL OF PHYSICAL CHEMISTRY A
(2021)
Review
Chemistry, Multidisciplinary
Sruthy Baburaj, Lakshmy Kannadi Valloli, Jayachandran Parthiban, Dipti Garg, Jayaraman Sivaguru
Summary: The control of photochemical reactions through hydrogen bonding is emphasized in order to develop Bronsted acid mediated photocatalysis.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Ravichandranath Singathi, Ramya Raghunathan, Retheesh Krishnan, Saravana Kumar Rajendran, Sruthy Baburaj, Mukund P. Sibi, Dean C. Webster, Jayaraman Sivaguru
Summary: Photodegradable, recyclable, and renewable crosslinked polymers from bioresources have the potential to address the issue of plastics degradability and recyclability.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Organic
Sunil Kumar Kandappa, Sapna Ahuja, Ravichandranath Singathi, Lakshmy Kannadi Valloli, Sruthy Baburaj, Jayachandran Parthiban, Jayaraman Sivaguru
Summary: This article highlights the role of restricted bond rotations in influencing the excited-state reactivity of organic molecules, and emphasizes the design strategies and methods for achieving selectivity in photochemical reactions.
Article
Chemistry, Physical
Ashish Sharma, Stavros Athanasopoulos, Yun Li, Samuel N. Sanders, Elango Kumarasamy, Luis M. Campos, Girish Lakhwani
Summary: This study investigates interchromophoric interactions in pentacene dimers using magnetic circular dichroism (MCD) spectroscopy. By analyzing experimental MCD spectra, the molecular structure of the bridging units was found to affect the through-space Coulombic and through-bond exchange interactions. The results demonstrate the significant through-bond interactions in dimers with conjugated molecules as bridging units, which promote the overall electronic coupling in the system.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Guiying He, Kaia Parenti, Peter Budden, Jens Niklas, Thomas Macdonald, Elango Kumarasamy, Xing Chen, Xiaodong Yin, Dane Mccamey, Oleg Poluektov, Luis Campos, Matthew Sfeir
Summary: This study investigates the evolution of molecular platforms for singlet fission (SF) chromophores and proposes characteristic optical markers to distinguish triplet pair formation from processes that generate an individual triplet. Covalently bound molecular dimers are used as a unique approach to achieve this. The SF effects of Acenothiophene and Anthradithiophene derivatives are also studied, revealing different dynamics due to functionalization of the heterocycle in Anthradithiophene.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Sapna Ahuja, Sruthy Baburaj, Lakshmy Kannadi Valloli, Sarvar Aminovich Rakhimov, Kavyasree Manal, Aakrati Kushwaha, Steffen Jockusch, Malcolm D. E. Forbes, Jayaraman Sivaguru
Summary: Aryl-maleimides undergo a novel [2+4]-photodimerization instead of the expected [2+2]-photodimerization, and the stereochemistry of the photodimer formed complements the product observed under thermal conditions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Biochemistry & Molecular Biology
Jayaraman Sivaguru, Thorsten Bach, Vaidhyanathan Ramamurthy
Summary: This perspective clarifies the terminology used for different [2 +2] photocycloaddition processes and aims to establish a standard to assist researchers in using the correct terminologies.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2022)
Article
Chemistry, Physical
Kaia R. Parenti, Guiying He, Samuel N. Sanders, Andrew B. Pun, Elango Kumarasamy, Matthew Y. Sfeir, Luis M. Campos
JOURNAL OF PHYSICAL CHEMISTRY A
(2020)
Review
Chemistry, Multidisciplinary
Sunil Kumar Kandappa, Lakshmy Kannadi Valloli, Sapna Ahuja, Jayachandran Parthiban, J. Sivaguru
Summary: This review discusses the excited state characteristics of imines and the processes governing their photochemical and photophysical properties, as well as pathways for deactivation and types of photochemical reactions. It also highlights recent strategies developed to address fundamental issues in the aza Paterno-Buchi reaction.
CHEMICAL SOCIETY REVIEWS
(2021)