Article
Chemistry, Multidisciplinary
Rong Hu, Yigao Tao, Xiaofeng Zhang, Weiping Su
Summary: In this study, a copper-catalyzed cascade reaction was reported, which produced novel γ-lactams through 1,2-aryl migration with a broad substrate scope and high yields. Mechanistically, the 1,2-aryl migration may be derived from the intramolecular amide C-N bond formation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Shutao Wang, Lianyou Zheng, Shaoli Song, Siyu Wang, Zhuoqi Zhang, Jinbao Xiang
Summary: A controllable and regiodivergent N-allylation reaction has been developed using O-alkyl hydroxamates derived from natural alpha-amino acids, enabling specific synthesis of alpha/beta-dipeptides containing unsaturated beta-amino acid moieties in moderate to good yields. The regioselectivity can be conveniently altered by changing the catalysts and solvents.
CHEMISTRY-AN ASIAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Habbanakuppe D. Preetham, Kothanahally S. Sharath Kumar, Aravind Kandaswamy, Shobith Rangappa, Mansour K. Gatasheh, Umashankara Muddegowda, Kanchugarakoppal S. Rangappa
Summary: A protocol for the preparation of 5-hydroxy-1H-pyrrol-2-(5H)-ones from easily available starting materials has been developed. The method involves the reaction of sulfur ylides with carbonyl compounds, leading to intramolecular cyclization and subsequent 1,3-hydroxy rearrangement to yield the desired product. The formation of 5-hydroxy-1H-pyrrol-2-(5H)-ones is supported by various spectroscopic techniques.
Article
Chemistry, Multidisciplinary
Nikita A. A. Shekhovtsov, Alexey A. A. Ryadun, Victor F. F. Plyusnin, Elena B. B. Nikolaenkova, Alexsei Ya. Tikhonov, Mark B. B. Bushuev
Summary: In this study, the proton transfer capabilities of a new class of ESIPT-capable molecules were investigated through experimental and theoretical studies. Different forms of the molecule with various emission wavelengths were observed in solutions, while only the ESIPT-capable form was found in the solid state. The ESIPT photoreaction in the ESIPT-capable form proceeded through a non-radiative deactivation process after overcoming a small energy barrier.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Organic
Keita Ashida, Yoichi Hoshimoto, Sensuke Ogoshi
Summary: A Ni(0)-catalyzed intramolecular carbonylative cycloaddition between 1,5-yne-imines and carbon monoxide was explored in this study. By using Ni(CO)(3)PCy(3) as a pre-catalyst, various polycyclic alpha,beta-unsaturated gamma-lactams were efficiently synthesized, with a yield of up to 78% and 100% atom efficiency. Aza-nickelacycles were confirmed as key intermediates, and diastereoselective transformations of the products led to highly substituted polycyclic gamma-lactams with three contiguous carbon stereocenters.
Article
Chemistry, Organic
Zhao-Fei Zhang, Zhong-Hua Gao, Chun-Lin Zhang, Song Ye
Summary: The intramolecular aza-Michael addition of alkyl amines to α,β-unsaturated carboxylic acids catalyzed by N-heterocyclic carbenes has been successfully achieved, allowing for the synthesis of pyrrolidine and piperidine derivatives. The use of chiral NHC catalysts demonstrated promising enantioselectivities up to 55% ee. Further chemical transformations of the products provided carboxylic acids, alcohols, and unprotected amines.
Article
Chemistry, Inorganic & Nuclear
Sagarmani Rasaily, Debesh Sharma, Sajan Pradhan, Nilankar Diyali, Shivanand Chettri, Bikram Gurung, Sudarsan Tamang, Anand Pariyar
Summary: Metal-organic frameworks (MOFs) offer the possibility to generate and stabilize coordinatively unsaturated sites (CUS), which are crucial for metal-centered catalysis. A solvothermal synthesis of a copper MOF (Cu-1D) that does not require activation has been reported, and it exhibits efficient catalytic activity in intermolecular and intramolecular cross-coupling reactions.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Dong Cheng, Xiangzhen Meng, Shuailu Wang, Xuan Zhao, Jingwen Chen
Summary: A facile method for the synthesis of substituted pyridines has been developed by NH4I-catalyzed cycloaddition of oxime acetates and alkyl pyruvate. The reaction proceeds through N-O bond cleavage and C-C bond formation, and shows mild conditions and high functional group compatibility.
Article
Crystallography
Hiroaki Iitsuka, Kun Li, Miyuki Kobayashi, Kikuko Iida, Noriyuki Yonezawa, Akiko Okamoto
Summary: The title compound exhibits triclinic symmetry at 193 K, with hydroxy and methoxy groups on the acenaphthene core displaying a cis configuration and forming a five-membered intramolecular O-H···O hydrogen-bonded ring. In the crystal, non-classical C-H···O hydrogen bonds form centrosymmetric dimeric structures, which are linked in the ac plane through non-classical C-H···F hydrogen bonds and C-H···π interactions.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2021)
