Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids
Published 2015 View Full Article
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Title
Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids
Authors
Keywords
Crystal structure, Molecular structure, Toxins, Snakebite, Venoms, Snakes, Sulfates, Neuromuscular blockade
Journal
PLoS One
Volume 10, Issue 7, Pages e0133370
Publisher
Public Library of Science (PLoS)
Online
2015-07-21
DOI
10.1371/journal.pone.0133370
References
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- (2013) Guilherme H.M. Salvador et al. TOXICON
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- LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery
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- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca2+-binding loop region for the catalytically inactive Lys49-PLA2s
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- (2010) David A Warrell LANCET
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
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- (2009) Daniela P. Marchi-Salvador et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Comparative structural studies on Lys49-phospholipases A2 from Bothrops genus reveal their myotoxic site
- (2009) Juliana I. dos Santos et al. JOURNAL OF STRUCTURAL BIOLOGY
- Influence of Quaternary Conformation on the Biological Activities of the Asp49-phospholipases A2s from Snake Venoms
- (2009) Angelo Magro et al. PROTEIN AND PEPTIDE LETTERS
- Understanding the in vitro neuromuscular activity of snake venom Lys49 phospholipase A2 homologues
- (2009) M. Gallacci et al. TOXICON
- Snake Envenoming: A Disease of Poverty
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- (2008) Xingding Zhou et al. BIOPHYSICAL JOURNAL
- Cellular pathology induced by snake venom phospholipase A2 myotoxins and neurotoxins: common aspects of their mechanisms of action
- (2008) C. Montecucco et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Antibothropic action ofCasearia sylvestris Sw. (Flacourtiaceae) extracts
- (2008) M. Cintra-Francischinelli et al. PHYTOTHERAPY RESEARCH
- The Global Burden of Snakebite: A Literature Analysis and Modelling Based on Regional Estimates of Envenoming and Deaths
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