In Vitro Induction of Endothelial Apoptosis of the Post-Hypoxic Blood-Brain Barrier by Isoflurane but Not by Sevoflurane and Midazolam

Isoflurane Anesthesia Initiated at the Onset of Reperfusion Attenuates Oxidative and Hypoxic-Ischemic Brain Injury

(2015) Sergey A. Sosunov et al.   PLoS One

Isoflurane reduces the ischemia reperfusion injury surge: A longitudinal study with MRI

(2014) Saeid Taheri et al.   BRAIN RESEARCH

Involvement of the blood–brain barrier opening in cognitive decline in aged rats following orthopedic surgery and high concentration of sevoflurane inhalation

(2014) Nan Hu et al.   BRAIN RESEARCH

Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke

(2014) Francisco J. Bezerra et al.   NEUROLOGICAL RESEARCH

Sevoflurane postconditioning provides neuroprotection against brain hypoxia–ischemia in neonatal rats

(2014) Xiaoyan Ren et al.   NEUROLOGICAL SCIENCES

Sevoflurane Anesthesia in Pregnant Mice Induces Neurotoxicity in Fetal and Offspring Mice

(2013) Hui Zheng et al.   ANESTHESIOLOGY

Stroke-Induced Brain Parenchymal Injury Drives Blood–Brain Barrier Early Leakage Kinetics: A Combined in Vivo/in Vitro Study

(2013) Mélanie Kuntz et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effect of Propofol Post-treatment on Blood–Brain Barrier Integrity and Cerebral Edema After Transient Cerebral Ischemia in Rats

(2013) Jae Hoon Lee et al.   NEUROCHEMICAL RESEARCH

Blood-Brain Barrier Breakdown after Embolic Stroke in Rats Occurs without Ultrastructural Evidence for Disrupting Tight Junctions

(2013) Martin Krueger et al.   PLoS One

Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory

(2012) Yiying Zhang et al.   ANNALS OF NEUROLOGY

Surgery Upregulates High Mobility Group Box-1 and Disrupts the Blood-Brain Barrier causing Cognitive Dysfunction in Aged Rats

(2012) Hui-Juan He et al.   CNS Neuroscience & Therapeutics

Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood-Brain Barrier Damage in Early Ischemic Stroke Stage

(2012) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Sevoflurane and Isoflurane Preconditioning Provides Neuroprotection by Inhibition of Apoptosis-related mRNA Expression in a Rat Model of Focal Cerebral Ischemia

(2012) Nurdan Bedirli et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

Isoflurane Induces Endothelial Apoptosis of the Post-Hypoxic Blood-Brain Barrier in a Transdifferentiated Human Umbilical Vein Edothelial Cell Model

(2012) Michael S. Dittmar et al.   PLoS One

Volatile Anesthetics Influence Blood-Brain Barrier Integrity by Modulation of Tight Junction Protein Expression in Traumatic Brain Injury

(2012) Serge C. Thal et al.   PLoS One

Isoflurane Attenuates Blood–Brain Barrier Disruption in Ipsilateral Hemisphere After Subarachnoid Hemorrhage in Mice

(2012) Orhan Altay et al.   STROKE

Resolving postoperative neuroinflammation and cognitive decline

(2011) Niccolò Terrando et al.   ANNALS OF NEUROLOGY

Inhibition of Sevoflurane Postconditioning Against Cerebral Ischemia Reperfusion-Induced Oxidative Injury in Rats

(2011) Yan Zhang et al.   MOLECULES

Isoflurane Enhanced Hemorrhagic Transformation by Impairing Antioxidant Enzymes in Hyperglycemic Rats With Middle Cerebral Artery Occlusion

(2011) Qin Hu et al.   STROKE

Toxic effects of midazolam on differentiating neurons in vitro as a consequence of suppressed neuronal Ca2+-oscillations

(2011) Barbara Sinner et al.   TOXICOLOGY

The Effects of Isoflurane Pretreatment on Cerebral Blood Flow, Capillary Permeability, and Oxygen Consumption in Focal Cerebral Ischemia in Rats

(2010) Oak Z. Chi et al.   ANESTHESIA AND ANALGESIA

Isoflurane Causes Greater Neurodegeneration Than an Equivalent Exposure of Sevoflurane in the Developing Brain of Neonatal Mice

(2010) Ge Liang et al.   ANESTHESIOLOGY

Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury via PI3K/Akt pathway

(2010) Jun-Kuan Wang et al.   BRAIN RESEARCH

Isoflurane preconditioning reduces oxygen–glucose deprivation-induced neuronal injury via B-cell lymphoma 2 protein

(2010) Mi-Sook Gwak et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Isoflurane Posttreatment Reduces Neonatal Hypoxic–Ischemic Brain Injury in Rats by the Sphingosine-1-Phosphate/Phosphatidylinositol-3-Kinase/Akt Pathway

(2010) Yilin Zhou et al.   STROKE

The Mitochondrial Pathway of Anesthetic Isoflurane-induced Apoptosis

(2009) Yiying Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cerebral Ischemia–Reperfusion Injury in Rats—A 3 T MRI Study on Biphasic Blood–Brain Barrier Opening and the Dynamics of Edema Formation

(2009) Deepu R Pillai et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Effects of Neonatal Isoflurane Exposure in Mice on Brain Cell Viability, Adult Behavior, Learning, and Memory

(2008) Andreas W. Loepke et al.   ANESTHESIA AND ANALGESIA

Opening of the blood-brain barrier during isoflurane anaesthesia

(2008) Samuel Tétrault et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The blood–brain barrier is continuously open for several weeks following transient focal cerebral ischemia

(2008) D. Strbian et al.   NEUROSCIENCE