Article
Chemistry, Organic
Yu Chen, Feng Zhao, Jun Tian, Le Jiang, Kai Lu, Yixuan Jiang, Hang Li, Shanshan Yu, Xiaoqi Yu, Lin Pu
Summary: A new red-light-emitting fluorescent probe (R)-5 was synthesized, showing good enantioselective fluorescence enhancement in the presence of Zn2+ and when combined with a green-light-emitting probe (S)-4 formed a pseudoenantiomeric sensor pair. This sensor pair can detect both enantiomers of chiral amino acids simultaneously at two very different wavelengths.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Yuki Matsuura, Masatoshi Asami, Suguru Ito
Summary: A chiral cation sensor consisting of two pyrene rings and a diethylene glycol linker has been developed to detect Al3+ and Cu2+ ions through differences in circular dichroism and fluorescence spectra. This sensor also revealed the formation of bipyrene structures triggered by Cu2+ cations, offering the potential for the development of dual-responsive fluorescent sensors capable of detecting two different analytes.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Organic
Fu-Ming Yang, Jun Luo, Yi-Chieh Chen, Wen-Sheng Chung
Summary: Inherently chiral calix[4]arenes were separated by condensation with chiral auxiliary (S)-and (R)-1-phenylethylamine using column chromatography on silica gel; subsequent derivatization with click chemistry resulted in compounds with fluorescent properties that can be used for chiral recognition.
SYNTHESIS-STUTTGART
(2023)
Review
Chemistry, Inorganic & Nuclear
Partha Roy
Summary: DFP is an important fluorophoric platform for the development of chemosensors with high selectivity and sensitivity. Compounds based on DFP can detect various metal ions, anions, neutral molecules, and pH ranges, offering a wide range of applications. The field of DFP-based chemosensors is emerging with plenty of opportunities for further research and development.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Analytical
Ming Xu, Jiajing Zhou, Yong Cheng, Zhicheng Jin, Alex E. Clark, Tengyu He, Wonjun Yim, Yi Li, Yu-Ci Chang, Zhuohong Wu, Pavla Fajtova, Anthony J. O'Donoghue, Aaron F. Carlin, Michael D. Todd, Jesse Jokerst
Summary: A novel self-immolative fluorescent probe (MP590) has been developed for the highly selective and sensitive detection of SARS-CoV-2 main protease (M-pro). This probe can measure and monitor M-pro activity and quantitatively evaluate M-pro inhibition in infected cells.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Shi Gang Liu, Shujuan Yang, Siyi Liu, Yuxiang Hu, Wenli Gao, Jiehong Deng, Xingbo Shi
Summary: In this study, a fluorescent and scattering dual-mode chemosensor for tetracycline (TC) was developed using a carbon dot@cerium-guanosine monophosphate (CD@GMP-Ce) coordination polymer. The dual-mode detection method based on TC-specific fluorescence and scattering decline exhibited low detection limits. The potential application of the dual-mode sensor was demonstrated in milk and tap-water samples.
ANALYTICAL METHODS
(2022)
Article
Chemistry, Inorganic & Nuclear
Gauri S. Malankar, Divyesh S. Shelar, M. Manikandan, Malay Patra, Ray J. Butcher, Sudesh T. Manjare
Summary: In this study, a BOPHY-based organotellurium-containing probe was synthesized and characterized for the selective and sensitive detection of Hg2+ over other metal ions. The probe showed a rapid response time of less than 1 second and a 2.5-fold increase in fluorescent intensity upon detection of Hg2+. It demonstrated nanomolar detection capability (62 nM) and reversibility with S2- ions. The probe's sensitivity for detecting Hg2+ was confirmed in living HeLa cells.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Analytical
Fenying Wang, Shuqing Xiong, Tingting Wang, Yadan Hou, Qianjin Li
Summary: In this study, a simple method using phenylboronic acid-functionalized fluorescent molecules and principal component analysis (PCA) was used to discriminate different types of cis-diols. By combining fluorescence response data and quenching constants with molecular weight, successful differentiation and identification of different types of cis-diols were achieved.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Multidisciplinary
Nicole Mertes, Marvin Busch, Magnus-Carsten Huppertz, Christina Nicole Hacker, Jonas Wilhelm, Clara-Marie Guerth, Stefanie Kuehn, Julien Hiblot, Birgit Koch, Kai Johnsson
Summary: We introduce a family of bright, rhodamine-based calcium indicators with tuneable affinities and colors. The indicators can be specifically localized to different cellular compartments and are compatible with both fluorescence and bioluminescence readouts through conjugation to HaloTag fusion proteins. Their increase in fluorescence upon localization enables no-wash live-cell imaging, facilitating their use in biological assays. These indicators are versatile and easy to use, making them powerful tools for bioimaging and bioassays.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Analytical
Fenying Wang, Shuqing Xiong, Tingting Wang, Yadan Hou, Qianjin Li
Summary: In this study, the discrimination and identification of different types of cis-diols were successfully achieved by combining fluorescent boronate affinity molecules with principal component analysis. By optimizing the fluorescence response data and quenching constants, the specific recognition capability of boronic acids was greatly improved, providing a simple and intuitive method for distinguishing and identifying different types of cis-diols.
ANALYTICAL METHODS
(2023)
Article
Spectroscopy
Xinke Wang, Xia Gao, Xiaodong Lin, Shuo Zheng, Yong Yan, Shuo Wang, Yaqing Liu
Summary: A reliable dual-channel assay using fluorescent and colorimetric detection has been developed for the rapid detection of silver ions. The assay shows high sensitivity and portability, and demonstrates excellent detection capabilities in real samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Inorganic & Nuclear
Ivan J. Bazany-Rodriguez, Maria K. Salomon-Flores, Alejandro O. Viviano-Posadas, Marco A. Garcia-Eleno, Joaquin Barroso-Flores, Diego Martinez-Otero, Alejandro Dorazco-Gonzalez
Summary: The new fluorescent Zn(ii)-terpyridine complexes are effective chemosensors for catecholamine-based neurotransmitters and nucleosides in water, showing high affinity and selectivity, with a blue emission that is quenched by the addition of l-DOPA and other compounds. The proposed binding mode between the Zn(ii)-chemosensors and l-DOPA involves a two-point recognition mechanism, including reversible esterification and coordination, as supported by multiple spectroscopic techniques and crystal structures.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Multidisciplinary
Meng-Xin Sun, Chuan-Zhi Ni, Fang-Qi Zhang, Yuan-Yuan Zhu, Jie Zeng, Shuang-Xi Gu
Summary: A novel BINOL-based fluorescence probe (S)-6 with excellent enantioselective recognition and fluorescent stability has been designed and synthesized for enantiomeric excess determination of amino acids.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Lidia A. Perez-Marquez, Marcelle D. Perretti, Raul Garcia-Rodriguez, Fernando Lahoz, Romen Carrillo
Summary: 3-Nitrotyrosine (NT) is an important biomarker of renal damage, but lacks an appropriate sensing method for clinical diagnosis. This study presents a fluorescent supramolecular sensor that selectively detects NT in human blood serum, providing a sensitive detection limit within physiological concentrations observed in chronic kidney disease.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Jiajie Luo, Hongyi Zhang, Jialiang Guan, Baoshuai An, Junli Peng, Wei Zhu, Ningning Wei, Yanru Zhang
Summary: A novel ratiometric fluorescent probe CARA was designed to detect lipase activity in human serum, showing high selectivity for lipase and potential for clinical diagnosis of acute pancreatitis. The probe breaks the FRET process between the energy donor and acceptor groups through a cleavable ester bond, demonstrating good linearity between fluorescence ratio and lipase activity in serum samples.
NEW JOURNAL OF CHEMISTRY
(2021)