Seneca Valley Virus 3Cpro Substrate Optimization Yields Efficient Substrates for Use in Peptide-Prodrug Therapy

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2013) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Characterization of a full-length infectious cDNA clone and a GFP reporter derivative of the oncolytic picornavirus SVV-001

(2012) J. T. Poirier et al.   JOURNAL OF GENERAL VIROLOGY

Targeting Carcinoma-Associated Fibroblasts Within the Tumor Stroma With a Fibroblast Activation Protein-Activated Prodrug

(2012) W. N. Brennen et al.   JNCI-Journal of the National Cancer Institute

Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy

(2012) S. R. Denmeade et al.   Science Translational Medicine

Protease-Activated Drug Development

(2012) Ki Young Choi et al.   Theranostics

Expression of proteins inEscherichia colias fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline

(2011) Stephen N. Hewitt et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Phase I Clinical Study of Seneca Valley Virus (SVV-001),a Replication-Competent Picornavirus, in Advanced Solid Tumors with Neuroendocrine Features

(2011) C. M. Rudin et al.   CLINICAL CANCER RESEARCH

A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models

(2010) L. Yu et al.   NEURO-ONCOLOGY

Initial testing of the replication competent Seneca Valley virus (NTX-010) by the pediatric preclinical testing program

(2010) Christopher L. Morton et al.   PEDIATRIC BLOOD & CANCER

Proteases: Multifunctional Enzymes in Life and Disease

(2008) Carlos López-Otín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complete genome sequence analysis of Seneca Valley virus-001, a novel oncolytic picornavirus

(2008) L. M. Hales et al.   JOURNAL OF GENERAL VIROLOGY

Structure of Seneca Valley Virus-001: An Oncolytic Picornavirus Representing a New Genus

(2008) Sangita Venkataraman et al.   STRUCTURE