The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function

The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells

(2013) Fernando Shahijanian et al.   HUMAN MOLECULAR GENETICS

Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season

(2013) Grant P Parnell et al.   Multiple Sclerosis Journal

Association of SNPs of CD40 Gene with Multiple Sclerosis in Russians

(2013) Ekaterina Alekseevna Sokolova et al.   PLoS One

Soluble IL7R  potentiates IL-7 bioactivity and promotes autoimmunity

(2013) W. Lundstrom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD19+CD24hiCD38hi B Cells Maintain Regulatory T Cells While Limiting TH1 and TH17 Differentiation

(2013) F. Flores-Borja et al.   Science Translational Medicine

A Genome-Wide Integrative Genomic Study Localizes Genetic Factors Influencing Antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1)

(2013) Rohina Rubicz et al.   PLoS Genetics

Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway

(2013) Gang Li et al.   PLoS Genetics

CD40 C/T-1 polymorphism plays different roles in Graves^|^rsquo; disease and Hashimoto^|^rsquo;s thyroiditis: a meta-analysis

(2012) Ming Li et al.   ENDOCRINE JOURNAL

Genetically Driven Target Tissue Overexpression of CD40: A Novel Mechanism in Autoimmune Disease

(2012) A. K. Huber et al.   JOURNAL OF IMMUNOLOGY

A common SNP in the CD40 region is associated with systemic lupus erythematosus and correlates with altered CD40 expression: implications for the pathogenesis

(2011) V. M. Vazgiourakis et al.   ANNALS OF THE RHEUMATIC DISEASES

Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L

(2011) Dae Kim et al.   Journal of Neuroinflammation

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Aberrant Cell Cycle and Apoptotic Changes Characterise Severe Influenza A Infection – A Meta-Analysis of Genomic Signatures in Circulating Leukocytes

(2011) Grant Parnell et al.   PLoS One

Understanding splicing regulation through RNA splicing maps

(2011) Joshua T. Witten et al.   TRENDS IN GENETICS

The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis

(2010) Kaushal S. Gandhi et al.   HUMAN MOLECULAR GENETICS

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Differential B-lymphocyte regulation by CD40 and its viral mimic, latent membrane protein 1

(2010) John P. Graham et al.   IMMUNOLOGICAL REVIEWS

Functionally Significant Differences in Expression of Disease-Associated IL-7 Receptor α Haplotypes in CD4 T Cells and Dendritic Cells

(2010) Edwin Hoe et al.   JOURNAL OF IMMUNOLOGY

CD40: Novel Association with Crohn's Disease and Replication in Multiple Sclerosis Susceptibility

(2010) Fiona Blanco-Kelly et al.   PLoS One

Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study

(2009) G. Orozco et al.   ANNALS OF THE RHEUMATIC DISEASES

Association of a single-nucleotide polymorphism inCD40with the rate of joint destruction in rheumatoid arthritis

(2009) Michael P. M. van der Linden et al.   ARTHRITIS AND RHEUMATISM

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

(2009) Melanie Bahlo et al.   NATURE GENETICS

Human Splicing Finder: an online bioinformatics tool to predict splicing signals

(2009) François-Olivier Desmet et al.   NUCLEIC ACIDS RESEARCH

The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance

(2008) Taishin Akiyama et al.   IMMUNITY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

(2008) Soumya Raychaudhuri et al.   NATURE GENETICS