Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity

LMTK2-mediated Phosphorylation Regulates CFTR Endocytosis in Human Airway Epithelial Cells

(2014) Simão Luz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation

(2014) Stan Pasyk et al.   PROTEOMICS

Second generation S1P pathway modulators: Research strategies and clinical developments

(2013) Marc Bigaud et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Capitalizing on diversity: an integrative approach towards the multiplicity of cellular mechanisms underlying myogenic responsiveness

(2012) Darcy Lidington et al.   CARDIOVASCULAR RESEARCH

Tumor Necrosis Factor-α–Mediated Downregulation of the Cystic Fibrosis Transmembrane Conductance Regulator Drives Pathological Sphingosine-1-Phosphate Signaling in a Mouse Model of Heart Failure

(2012) Anja Meissner et al.   CIRCULATION

Proximal Cerebral Arteries Develop Myogenic Responsiveness in Heart Failure via Tumor Necrosis Factor-α–Dependent Activation of Sphingosine-1-Phosphate Signaling

(2012) Jingli Yang et al.   CIRCULATION

The Role of Sphingosine Kinase 1/Sphingosine-1-Phosphate Pathway in the Myogenic Tone of Posterior Cerebral Arteries

(2012) Mihwa Lim et al.   PLoS One

Rescue of ΔF508-CFTR Trafficking via a GRASP-Dependent Unconventional Secretion Pathway

(2011) Heon Yung Gee et al.   CELL

Probing Conformational Rescue Induced by a Chemical Corrector of F508del-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mutant

(2011) Wilson Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of cell background on pharmacological rescue of mutant CFTR

(2010) Nicoletta Pedemonte et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Sphingosine-1-Phosphate–Dependent Activation of p38 MAPK Maintains Elevated Peripheral Resistance in Heart Failure Through Increased Myogenic Vasoconstriction

(2010) Judith Hoefer et al.   CIRCULATION RESEARCH

The Phosphorylation Motif at Serine 225 Governs the Localization and Function of Sphingosine Kinase 1 in Resistance Arteries

(2009) Darcy Lidington et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanism and Role of High Density Lipoprotein-induced Activation of AMP-activated Protein Kinase in Endothelial Cells

(2009) Takao Kimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Small-Molecule Modulator Interacts Directly with  Phe508-CFTR to Modify Its ATPase Activity and Conformational Stability

(2009) L. Wellhauser et al.   MOLECULAR PHARMACOLOGY

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease

(2008) Stan Pasyk et al.   BIOCHEMICAL JOURNAL

Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator

(2008) A Schmidt et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of Sphingosine-1-Phosphate Phosphohydrolase 1 in the Regulation of Resistance Artery Tone

(2008) Bernhard Friedrich Peter et al.   CIRCULATION RESEARCH

The regulation of AMP-activated protein kinase by upstream kinases

(2008) D Carling et al.   INTERNATIONAL JOURNAL OF OBESITY

Mechanistic Insight into Control of CFTR by AMPK

(2008) Patthara Kongsuphol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY