4.8 Article

Microelectrode arrays and ceric ammonium nitrate: A simple strategy for developing new site-selective synthetic methods

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 130, Issue 34, Pages 11290-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja804661h

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Funding

  1. National Science Foundation [CHE-9023698]
  2. NIH [RR02004, RR05018, RR07155]
  3. Washington University Mass Spectrometry Resource Center [NIHRR00954]

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Conditions for a site-selective ceric ammonium nitrate oxidation have been developed. The reactions proceed nicely on both 1K- and 12K-microelectrode arrays. The procedure for developing the reactions was very simple and demonstrated that the same reagents used for a solution-phase reaction can be used for a related site-selective reaction on a microelectrode array.

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