Article
Multidisciplinary Sciences
Rachel Paul, Guillaume Giraud, Katrin Domsch, Marilyne Duffraisse, Frederic Marmigere, Soumen Khan, Solene Vanderperre, Ingrid Lohmann, Robby Stoks, L. S. Shashidhara, Samir Merabet
Summary: The authors demonstrate that the Hox genes Antennapedia (Antp) and Ultrabithorax (Ubx) play a role in controlling flight appendage morphology in Drosophila, with a particular spatial expression profile and dosage. Interestingly, this phenomenon is also found in evolutionary distant four-winged insect species.
NATURE COMMUNICATIONS
(2021)
Article
Psychology, Multidisciplinary
Weiqiao Fan, Mengting Li, Xinyin Chen
Summary: This study explored the reciprocal relations between parenting styles and adolescents' interpersonal personality in China. The results showed that perceived paternal rejection and behavioral controlling could negatively or positively predict adolescents' interpersonal relatedness, while maternal rejection and parental filial piety also played significant roles in influencing adolescents' interpersonal personality. These findings highlight the importance of parenting styles in shaping adolescents' interpersonal relationships and personality development.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Cell Biology
Kathleen S. M. Reed, Eric S. Davis, Marielle L. Bond, Alan Cabrera, Eliza Thulson, Ivana Yoseli Quiroga, Shannon Cassel, Kamisha T. Woolery, Isaac Hilton, Hyejung Won, Michael I. Love, Douglas H. Phanstiel
Summary: In this study, potential causal relationships between 3D chromatin structure, enhancers, and gene transcription were investigated using genome-wide mapping in macrophage activation. The results suggest that chromatin loops can facilitate transcription by connecting promoters to distal enhancers, while high levels of transcription may impede loop formation.
Article
Medicine, General & Internal
In-Hee Lee, Douglas I. Walker, Yufei Lin, Matthew Ryan Smith, Kenneth D. Mandl, Dean P. Jones, Sek Won Kong
Summary: This study found an association between plasma glutamine levels and clinical phenotypes in individuals with autism spectrum disorder (ASD), suggesting that plasma glutamine levels could serve as an endophenotype linking genetic risk and symptom severity. These findings may contribute to the development of novel therapeutic targets, selection of specific cohorts for clinical trials, and identification of target symptoms for future ASD treatment strategies.
Article
Biology
Murat Yasar, Fatih Hilmi Cetin, Serhat Turkoglu, Halit Necmi Ucar
Summary: The aim of this study was to investigate the executive functions in healthy siblings of children with Autism Spectrum Disorder (ASD) and examine the relationship between chronotype and executive functions. The study included 40 healthy siblings (case group) of children with ASD and 40 healthy controls. The Stroop Test and Cancellation Test performances were significantly worse in the case group compared to the control group. The total Chronotype Questionnaire (CCTQ) score was significantly higher in the case group, and there was a positive correlation between chronotype score and false targets in the Cancellation Test.
CHRONOBIOLOGY INTERNATIONAL
(2023)
Article
Neurosciences
Seoyoung Lee, In-Seon Lee, Younbyoung Chae
Summary: This study explored the relationship between acupuncture points and myofascial trigger points (TPs) and found that TPs are closely related to Ashi points. However, TPs also share some features with other acupuncture points, making it difficult to clarify their relationship with other subgroups.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Geriatrics & Gerontology
Pildoo Sung, Arthur Chia, Angelique Chan, Rahul Malhotra
Summary: Lifelong learning and volunteering have a reciprocal relationship, with non-job-related lifelong learning predicting volunteering, and volunteering predicting both job-related and non-job-related lifelong learning. These findings suggest that promoting and providing opportunities for both lifelong learning and volunteering can create a virtuous circle of productive social engagement in later life.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Amy N. Costa, Bradley J. Ferguson, Emily Hawkins, Adriana Coman, Joseph Schauer, Alex Ramirez-Celis, Patrick M. Hecht, Danielle Bruce, Michael Tilley, Zohreh Talebizadeh, Judy van de Water, David Q. Beversdorf
Summary: This study investigates the relationship between prenatal stress and maternal antibody response and the diagnosis of autism spectrum disorder (ASD) in children. The study found that although there were high incidences of prenatal stress and maternal antibodies in the sample, they were not associated with each other. The results suggest that prenatal stress and immune dysregulation are independently associated with a diagnosis of ASD, rather than acting through a convergent mechanism. However, further research with a larger sample is needed to confirm these findings.
Article
Biochemistry & Molecular Biology
Isabella Bonilha, Eric Hajduch, Beatriz Luchiari, Wilson Nadruz, Wilfried Le Goff, Andrei C. Sposito
Summary: Type 2 diabetes mellitus and insulin resistance result in significant modifications to the lipoprotein profile, including an increased proportion of smaller and denser LDL particles. These changes also impact the composition and structure of LDL, leading to functional alterations that raise the risk of cardiovascular disease in diabetic individuals. Therapeutic strategies targeting LDL are discussed as potential interventions in managing diabetes-related cardiovascular risks.
Article
Multidisciplinary Sciences
Tetsuhiro. S. Hatakeyama, Kunihiko Kaneko
Summary: In the physics of living systems, understanding the relationship between macroscopic variables and microscopic elements is crucial. By evolving gene regulatory networks, we observed that certain core genes remained stable while other genes exhibited plasticity in response to environmental changes. An autonomous feedforward structure evolved from non-core to core genes. This study revealed a reciprocity between the robustness of homeostatic genes and the plasticity of regulator genes, which is constrained by the ratio of these genes.
Article
Neurosciences
Mukaddes Karaca, Reyhan Tahtasakal, Halime Dana, Murside Sahin, Seyda Nur Pirencioglu, Emre Tughan, Fatma Dal, Esra Demirci, Elif Funda Sener
Summary: This study compares the gene expression and serum α-synuclein levels in autistic patients, their healthy siblings, and healthy controls. It was found that serum α-synuclein levels were significantly decreased in autistic patients and their mothers, and there was a significant negative correlation between SNCA gene expression and protein levels in the patients aged 6-8.
Article
Neurosciences
Mirko Uljarevic, Thomas W. Frazier, Booil Jo, Jennifer M. Phillips, Wesley Billingham, Matthew N. Cooper, Antonio Y. Hardan
Summary: The study found that impairments in social motivation in children with ASD may be driven, in part, by lower social motivation in one or both parents. Future research should delve into more related factors to explain individual differences in sociability.
FRONTIERS IN NEUROSCIENCE
(2021)
Review
Clinical Neurology
Maison Abu Raya, Adedoyin O. Ogunyemi, Veronica Rojas Carstensen, Jake Broder, Maryenela Illanes-Manrique, Katherine P. Rankin
Summary: The desire for novelty and variety in experiences, known as Openness to Experience, is associated with engaging with individuals from diverse cultural backgrounds. This openness is positively correlated with creativity and has sparked scholarly interest in the fields of personality psychology, social psychology, organizational psychology, and neuroscientific investigation. Culture influences levels of openness and creativity, and creativity predisposes individuals toward openness to experiences in culturally diverse contexts. The reciprocal relationship between creativity and openness reduces biases, enhances conflict resolution capabilities, and leads to better outcomes in multicultural environments.
FRONTIERS IN NEUROLOGY
(2023)
Article
Psychology, Developmental
Alliyza Lim, Neil Brewer, Robyn L. Young
Summary: An online survey found that individuals on the autism spectrum were more likely to engage in cybercrime than those without autism, but this was not influenced by advanced digital skills or deficits in theory of mind. Autistic traits were also not significantly associated with self-reported cyber-criminality. Other factors such as specific autistic characteristics, understanding of cybercrime, and willingness to disclose criminal activity may moderate the relationship between autism, autistic traits, and cybercrime.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Psychiatry
L. Dell'Osso, G. Amatori, G. Massimetti, B. Nardi, D. Gravina, F. Benedetti, C. Bonelli, M. Luciano, I. Berardelli, N. Brondino, M. De Gregorio, G. Deste, M. Nola, A. Reitano, M. R. A. Muscatello, M. Pompili, P. Politi, A. Vita, C. Carmassi, M. Maj
Summary: This study reveals a strong correlation between the autism spectrum and catatonia, particularly in terms of sensory reactivity, communication abilities, restricted interests, and adherence to routines.
EUROPEAN PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Young Jae Woo, Tao Wang, Tulio Guadalupe, Rebecca A. Nebel, Arianna Vino, Victor A. Del Bene, Sophie Molholm, Lars A. Ross, Marcel P. Zwiers, Simon E. Fisher, John J. Foxe, Brett S. Abrahams
Article
Biochemistry & Molecular Biology
Michael A. Balamotis, Nele Tamberg, Young Jae Woo, Jingchuan Li, Brian Davy, Terumi Kohwi-Shigematsu, Yoshinori Kohwi
MOLECULAR AND CELLULAR BIOLOGY
(2012)
Article
Multidisciplinary Sciences
Jae Hoon Jeong, Young Jae Woo, Streamson Chua, Young-Hwan Jo
Article
Neurosciences
Young Jae Woo, Alexandros K. Kanellopoulos, Parisa Hemati, Jill Kirschen, Rebecca A. Nebel, Tao Wang, Claudia Bagni, Brett S. Abrahams
BIOLOGICAL PSYCHIATRY
(2019)
Article
Medicine, General & Internal
Young Jae Woo, Panos Roussos, Vahram Haroutunian, Pavel Katsel, Samuel Gandy, Eric E. Schadt, Jun Zhu
Article
Biochemistry & Molecular Biology
Alexandros K. Kanellopoulos, Vittoria Mariano, Marco Spinazzi, Young Jae Woo, Colin McLean, Ulrike Pech, Ka Wan Li, J. Douglas Armstrong, Angela Giangrande, Patrick Callaerts, August B. Smit, Brett S. Abrahams, Andre Fiala, Tilmann Achsel, Claudia Bagni
Article
Audiology & Speech-Language Pathology
Lars A. Ross, Victor A. Del Bene, Sophie Molholm, Young Jae Woo, Gizely N. Andrade, Brett S. Abrahams, John J. Foxe
BRAIN AND LANGUAGE
(2017)