Editorial Material
Multidisciplinary Sciences
Elena Garralda, Scott A. Laurie, Lesley Seymour, Elisabeth G. E. de Vries
Summary: Early detection of immunotherapy-induced tumor response is crucial, but therapy-induced pseudoprogression can make it complicated. A consensus guideline called iRECIST, a modification of RECIST version 1.1, was developed. This article explores the next steps required to test its validity and proposes novel approaches for response criteria.
NATURE COMMUNICATIONS
(2023)
Article
Pediatrics
Elizabeth R. Wolf, Alicia Richards, Martin Lavallee, Roy T. Sabo, Alan R. Schroeder, Matthew Schefft, Alex H. Krist
Summary: Overuse in bronchiolitis remains common and occurs frequently in emergency and outpatient settings as well as rural locations. Quality improvement initiatives aimed at reducing overuse should include these clinical environments.
Article
Nursing
Sangita Pudasainee-Kapri
Summary: The study aimed to improve providers' adherence to asthma guidelines through education and implementation of guidelines, leading to enhanced care for asthma patients. Results showed improvement in utilization of key guideline elements, such as assessment, medication adherence, and follow-up visits, among providers.
JOURNAL OF PEDIATRIC NURSING-NURSING CARE OF CHILDREN & FAMILIES
(2021)
Article
Respiratory System
Annette Evans, Daniel Farewell, Joanne Demmler, Amrita Bandyopadhyay, Colin Victor Eric Powell, Shantini Paranjothy
Summary: The study suggests that children with inpatient asthma admissions are at higher risk of not attaining expected educational levels at age 6-7, while lower respiratory tract infection GP contacts are an independent predictor of poor educational outcomes. School absence may mediate the relationship between inpatient asthma admissions and educational attainment.
Article
Nutrition & Dietetics
Arne Astrup, Nina Teicholz, Faidon Magkos, Dennis M. Bier, J. Thomas Brenna, Janet C. King, Andrew Mente, Jose M. Ordovas, Jeff S. Volek, Salim Yusuf, Ronald M. Krauss
Summary: Research in the past decade has shown a lack of rigorous evidence to support continued recommendations to limit saturated fats or replace them with polyunsaturated fats. However, recent U.S. Dietary Guidelines still recommend limiting saturated fats to 10% of total energy intake without considering the findings of these studies. This recommendation also overlooks the important effects of the food matrix and overall dietary pattern when consuming saturated fatty acids.
Article
Gastroenterology & Hepatology
James Buxbaum, Bashar Qumseya, Sachin Wani
Summary: Despite the lack of consensus criteria for the diagnosis of cholangitis, the BILE criteria appears to be a promising approach in identifying high-risk patients. Further validation studies are needed to confirm its diagnostic performance and ability to prevent unnecessary ERCP.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Raj Shah, Sagarika Satyavada, Michael Kurin, Mayada Ismail, Zachary L. Smith, Perica Davitkov, Gerard Isenberg, Gottumukkala S. Raju, Ashley Faulx, Yngve Falck-Ytter, Amitabh Chak
Summary: This study created a unique and effective educational platform based on evidence-based medicine principles to address the lack of evidence-based endoscopy teaching platforms. The platform incorporates low fidelity simulation and was well-received by participants, indicating a strong desire for this type of educational product. It fills a gap in available tools for endoscopy education.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Endocrinology & Metabolism
Petros Perros, Krishnarajah Nirantharakumar, Laszlo Hegedues
Summary: Clinicians typically advise hypothyroid patients to maintain normal serum TSH levels, but recent research suggests that mortality rates increase when serum TSH levels are either elevated or reduced outside the normal range. Therefore, optimal control of serum TSH is crucial for patients undergoing L-T4 replacement therapy.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2021)
Review
Gastroenterology & Hepatology
Hitoshi Yoshiji, Sumiko Nagoshi, Takemi Akahane, Yoshinari Asaoka, Yoshiyuki Ueno, Koji Ogawa, Takumi Kawaguchi, Masayuki Kurosaki, Isao Sakaida, Masahito Shimizu, Makiko Taniai, Shuji Terai, Hiroki Nishikawa, Yoichi Hiasa, Hisashi Hidaka, Hiroto Miwa, Kazuaki Chayama, Nobuyuki Enomoto, Tooru Shimosegawa, Tetsuo Takehara, Kazuhiko Koike
Summary: The latest edition of the clinical practice guidelines for liver cirrhosis includes new background and future research questions, as well as updates based on international standards and recent findings. It covers various aspects of liver cirrhosis treatment, complication management, and clinically important issues, incorporating the latest information and references to international guidelines.
JOURNAL OF GASTROENTEROLOGY
(2021)
Review
Respiratory System
Christina Baggott, Jo Katherine Hardy, Jenny Sparks, Donah Sabbagh, Richard Beasley, Mark Weatherall, James Fingleton
Summary: The systematic review found that epinephrine and selective beta(2)-agonists have similar efficacy in acute asthma, but there is low-quality evidence and a need for high-quality double-blind RCTs to determine if the addition of intramuscular epinephrine to inhaled or nebulised selective beta(2)-agonist improves outcomes.
Review
Medicine, General & Internal
Adnan Liaqat, Mathew Mason, Brian Foster, Grant Gregory, Avani Patel, Aisha Barlas, Sagar Kulkarni, Rafaela Basso, Pooja Patak, Hamza Liaqat, Muhammad Qureshi, Abdelrahman Shehata, Yousef Awad, Mina Ghaly, Qamar Gulzar, Walter Doty
Summary: The use of biologic agents in the treatment of bronchial asthma has greatly improved the quality of life and reduced morbidity and healthcare utilization. These therapies target specific inflammatory pathways, particularly improving outcomes in severe eosinophilic asthma. Tezepelumab, a newer agent targeting thymic stromal lymphoprotein, has shown effectiveness in patients regardless of asthma phenotype and serum biomarker levels.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Urology & Nephrology
Daniel A. Gonzalez-Padilla, Philipp Dahm
Summary: GRADE is a rigorous and transparent framework for grading the certainty of evidence and making recommendations. Recommendations can be strong or weak for or against an intervention, based on factors like evidence certainty, desirable and undesirable outcomes, patient values, and resource use. This approach is essential for guideline development in healthcare.
EUROPEAN UROLOGY FOCUS
(2021)
Article
Allergy
Bradley E. Chipps, Kevin R. Murphy, John Oppenheimer
Summary: This article compares the guidelines from the 2020 National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group and the 2021 strategy report from the Global Initiative for Asthma. It discusses the methodologies of each publication, as well as compares the selected pharmacological recommendations and nonpharmacological recommendations in the two documents.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2022)
Article
Computer Science, Interdisciplinary Applications
Gregor Lichtner, Brian S. Alper, Carlo Jurth, Claudia Spies, Martin Boeker, Joerg J. Meerpohl, Falk von Dincklage
Summary: This study proposes a FHIR-based format that uses computer-interpretable representations of knowledge artifacts to directly generate evidence-based recommendations. An information model and corresponding representation based on FHIR resources were developed, allowing for the transparent evaluation of evidence and the facilitation of computer-interpretable guideline recommendations.
JOURNAL OF BIOMEDICAL INFORMATICS
(2023)
Article
Allergy
Gandhi Fernando Pavon-Romero, Ramces Falfan-Valencia, Katia Vanessa Gutierrez-Quiroz, Estivaliz Arizel De La O-Espinoza, Nancy Haydee Serrano-Perez, Fernando Ramirez-Jimenez, Luis M. Teran
Summary: This study aimed to evaluate lung function and clinical control of asthma in patients with N-ERD over a three-year period using GINA guidelines. The results showed that N-ERD patients had better lung function and clinical control at baseline compared to asthma patients. However, as the treatment progressed, the lung function in asthma patients improved and the clinical control became similar between the two groups after the second year.
JOURNAL OF ASTHMA AND ALLERGY
(2023)
Article
Oncology
Betsy Risendal, John M. Westfall, Linda Zittleman, Carol Hodgson, Timothy Garrington, Christin Sutter, Lori Jarrell, William LeBlanc, Linda Overholser
Summary: With an increasing number of cancer survivors and an aging population, primary care providers are faced with more patients with a history of cancer. This study developed a survivorship education program for rural primary care practices and evaluated its impact. The results showed positive outcomes, with increased knowledge and intention to change care delivery. The study highlights the importance of supporting primary care practices in meeting the needs of cancer survivors.
JOURNAL OF CANCER EDUCATION
(2022)
Article
Health Care Sciences & Services
John M. Westfall, Hope R. Wittenberg, Winston Liaw
JOURNAL OF GENERAL INTERNAL MEDICINE
(2021)
Article
Health Care Sciences & Services
Kristen Curcija, Linda Zittleman, Mary Fisher, Donald E. Nease, L. Miriam Dickinson, Dionisia de la Cerda, Christin Sutter, Jen Ancona, James Rank, John M. Westfall
Summary: This study aims to increase awareness and promote positive attitudes towards OUD and MAT among rural community members through the development of community-based interventions. The findings show that exposure to these interventions is associated with beliefs such as the acknowledgement of opioid abuse as a problem in rural areas, the recognition of opioid addiction as a chronic disease, and the belief that OUD can be treated locally.
JOURNAL OF RURAL HEALTH
(2022)
Article
Education, Scientific Disciplines
Robert L. Phillips, Brian C. George, Eric S. Holmboe, Andrew W. Bazemore, John M. Westfall, Asaf Bitton
Summary: The GME system heavily relies on public funding to produce physicians that meet society's needs, but there is a lack of public accountability in how this funding is used. However, assessing GME outcomes and guiding training improvement can lead to a better alignment with public needs.
Article
Primary Health Care
Linda Zittleman, Kristen Curcija, Donald E. Nease, Mary Fisher, L. Miriam Dickinson, John F. Thomas, Ashley Espinoza, Christin Sutter, Jennifer Ancona, Jodi Summers Holtrop, John M. Westfall
Summary: The study aimed to increase rural PCPs providing buprenorphine treatment for OUD through practice team training. Results showed a significant improvement in treatment implementation and delivery, with an increase in the number of practices providing or referring patients for treatment, and a greater number of people with a buprenorphine prescription in the study region compared to the rest of the state.
ANNALS OF FAMILY MEDICINE
(2022)
Article
Primary Health Care
Hoon Byun, John M. Westfall
Summary: The study examines the scope of practice among family physicians and highlights the potential for their redeployment during emergencies. It found that while most family physicians practice at a single site, those in rural areas have a broader scope, indicating their capacity for deployment in different settings.
Article
Primary Health Care
Natalia Y. Loskutova, Elisabeth F. Callen, John M. Westfall
Summary: This study, conducted through an online survey, found variations in assessments and tools used during the Medicare Annual Wellness Visit (AWV). The results indicated a need for more comprehensive evaluation content and a preference for structured and objective assessment methods.
JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE
(2022)
Article
Medical Informatics
Winston R. Liaw, John M. Westfall, Tyler S. Williamson, Yalda Jabbarpour, Andrew Bazemore
Summary: A recently released report from the National Academy of Medicine suggests that the use of artificial intelligence (AI) outside of hospitals, such as conversational agents, cameras, and remote sensors, has the potential to improve health. However, the success of AI is not guaranteed, and stakeholders need to be involved in its development to ensure easy usability by clinicians, protection of patient privacy, and enhanced value of care. Primary care, as the largest healthcare delivery platform, plays a crucial role in the adoption and potential exacerbation of health disparities. To fully leverage the benefits of AI, primary care needs to become a medical home for AI, expanding its teams and training, and capitalizing on government initiatives and funding.
JMIR MEDICAL INFORMATICS
(2022)
Letter
Primary Health Care
John M. Westfall, Erin C. Westfall
Article
Public, Environmental & Occupational Health
Danielle Hessler, Lawrence Fisher, Miriam Dickinson, Perry Dickinson, Jose Parra, Michael B. Potter
Summary: This study compares an evidence-based self-management support program for type 2 diabetes with an enhanced version that includes a patient engagement protocol. Both programs resulted in significant improvements in self-management behaviors, psychological outcomes, and social risks for patients. The enhanced version showed greater improvements in psychological outcomes and behavioral self-management.
TRANSLATIONAL BEHAVIORAL MEDICINE
(2022)
Article
Medicine, General & Internal
Derek J. Baughman, Yalda Jabbarpour, John M. Westfall, Anuradha Jetty, Areeba Zain, Kathryn Baughman, Brian Pollak, Abdul Waheed
Summary: This retrospective study compared the quality of care between telemedicine and in-person office visits. The results showed that telemedicine had a largely favorable association with quality of primary care, especially in chronic disease management and preventive care.
Editorial Material
Health Care Sciences & Services
Jodi Polaha, John M. Westfall, Candice Chen
FAMILIES SYSTEMS & HEALTH
(2022)
Article
Primary Health Care
Nick DeVetter, John M. Westfall, Mark Carrozza, Erin Westfall
Summary: This study aimed to describe the searches made by users on the Neighborhood Navigator tool and identify patterns to inform resource allocation. The results showed that the most common searches were for food and housing insecurity, as well as healthcare referral, with more searches in winter than in spring. There was a significant increase in searches during the study period, particularly during the COVID-19 pandemic. This analysis can help clinicians, practices, and health systems prepare for the most common social needs of their patients.
JOURNAL OF PRIMARY CARE AND COMMUNITY HEALTH
(2022)
Article
Primary Health Care
Rita K. Kuwahara, Yalda Jabbarpour, John M. Westfall
Summary: In order to combat the increasing incidence of acute hepatitis B, ACIP now recommends universal hepatitis B vaccination for adults aged 19 to 59. However, a national survey found that most family physicians are unaware of or have not fully implemented this recommendation. Targeted efforts by training institutions, medical systems, and physician organizations will be crucial in raising awareness and preventing the disease.
AMERICAN FAMILY PHYSICIAN
(2022)
Article
Health Policy & Services
Jodi Summers Holtrop, Rebecca Mullen, Kristen Curcija, John M. Westfall, Linda Zittleman
Summary: MAT is an evidence-based solution for opioid use disorder (OUD), but its availability in rural areas is limited. This study explored the views of healthcare professionals on OUD and MAT, particularly buprenorphine treatment, in rural primary care practices. The findings suggest that the lack of local resources, emotional burden, and hesitancy towards buprenorphine treatment are key barriers to MAT implementation. However, many practices expressed interest in learning more to help their communities.
JOURNAL OF HEALTH CARE FOR THE POOR AND UNDERSERVED
(2022)