CD8+ T Cell Response to Gammaherpesvirus Infection Mediates Inflammation and Fibrosis in Interferon Gamma Receptor-Deficient Mice

Extensive Phenotyping of Individuals at Risk for Familial Interstitial Pneumonia Reveals Clues to the Pathogenesis of Interstitial Lung Disease

(2015) Jonathan A. Kropski et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

(2014) Talmadge E. King et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

(2014) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung

(2013) Alexander V. Misharin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Animal Models of Fibrotic Lung Disease

(2013) Bethany B. Moore et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pathogenesis of Idiopathic Pulmonary Fibrosis

(2013) Paul J. Wolters et al.   Annual Review of Pathology-Mechanisms of Disease

CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model

(2013) Anne-Gaëlle Besnard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Absence of M1 Leads to Increased Establishment of Murine Gammaherpesvirus 68 Latency in IgD-Negative B Cells

(2013) L. T. Krug et al.   JOURNAL OF VIROLOGY

Peripheral Blood Mononuclear Cell Gene Expression Profiles Predict Poor Outcome in Idiopathic Pulmonary Fibrosis

(2013) J. D. Herazo-Maya et al.   Science Translational Medicine

Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis

(2012) J. A. Kropski et al.   Disease Models & Mechanisms

A neutrophil elastase inhibitor prevents bleomycin-induced pulmonary fibrosis in mice

(2012) Akihiro Takemasa et al.   EUROPEAN RESPIRATORY JOURNAL

 -Herpesvirus Reactivation Differentially Stimulates Epitope-Specific CD8 T Cell Responses

(2012) M. L. Freeman et al.   JOURNAL OF IMMUNOLOGY

Prednisone, Azathioprine, andN-Acetylcysteine for Pulmonary Fibrosis

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Right place, right time: the evolving role of herpesvirus infection as a “second hit” in idiopathic pulmonary fibrosis

(2011) Jonathan A. Kropski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The distribution of immunomodulatory cells in the lungs of patients with idiopathic pulmonary fibrosis

(2011) Gerard J Nuovo et al.   MODERN PATHOLOGY

Inhibition of NF-κB Signaling Reduces Virus Load and Gammaherpesvirus-Induced Pulmonary Fibrosis

(2010) Laurie T. Krug et al.   AMERICAN JOURNAL OF PATHOLOGY

Latent infection by γherpesvirus stimulates profibrotic mediator release from multiple cell types

(2010) Joshua S. Stoolman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Latent Herpesvirus Infection Augments Experimental Pulmonary Fibrosis

(2010) Kevin M. Vannella et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Epstein-Barr Virus Latent Membrane Protein 1 and Transforming Growth Factor–β1 Synergistically Induce Epithelial–Mesenchymal Transition in Lung Epithelial Cells

(2010) Mark D. Sides et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Murine Gammaherpesvirus 68 LANA Is Essential for Virus Reactivation from Splenocytes but Not Long-Term Carriage of Viral Genome

(2010) C. R. Paden et al.   JOURNAL OF VIROLOGY

Two Kinetic Patterns of Epitope-Specific CD8 T-Cell Responses following Murine Gammaherpesvirus 68 Infection

(2010) M. L. Freeman et al.   JOURNAL OF VIROLOGY

CD28 Down-Regulation on Circulating CD4 T-Cells Is Associated with Poor Prognoses of Patients with Idiopathic Pulmonary Fibrosis

(2010) Syed R. Gilani et al.   PLoS One

Viral infection and aging as cofactors for the development of pulmonary fibrosis

(2010) Payal K Naik et al.   Expert Review of Respiratory Medicine

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Murine Gammaherpesvirus 68 Infection of IFNγ Unresponsive Mice: A Small Animal Model for Gammaherpesvirus-Associated B-Cell Lymphoproliferative Disease

(2009) Katherine S. Lee et al.   CANCER RESEARCH

EFFECTS OF ELASTASE INHIBITOR ON THE EPITHELIAL CELL APOPTOSIS IN BLEOMYCIN-INDUCED PULMONARY FIBROSIS

(2009) Jeong Sup Song et al.   EXPERIMENTAL LUNG RESEARCH

Twist: A Regulator of Epithelial-Mesenchymal Transition in Lung Fibrosis

(2009) Veronika Pozharskaya et al.   PLoS One

Alveolar epithelial cell injury with Epstein-Barr virus upregulates TGFβ1 expression

(2008) Andrea P. Malizia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A gammaherpesvirus-secreted activator of Vβ4+CD8+T cells regulates chronic infection and immunopathology

(2008) Andrew G. Evans et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Idiopathic pulmonary fibrosis

(2008) Eric B Meltzer et al.   Orphanet Journal of Rare Diseases

Murine models of pulmonary fibrosis

(2007) Bethany B. Moore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Role of Inflammation in the Pathogenesis of Idiopathic Pulmonary Fibrosis

(2007) Benjamin D. Bringardner et al.   ANTIOXIDANTS & REDOX SIGNALING