Article
Multidisciplinary Sciences
Jonathan Z. Butler, Mariam Carson, Francine Rios-Fetchko, Roberto Vargas, Abby Cabrera, Angela Gallegos-Castillo, Monique LeSarre, Michael Liao, Kent Woo, Randi Ellis, Kirsten Liu, Arun Burra, Mario Ramirez, Brittney Doyle, Lydia Leung, Alicia Fernandez, Kevin Grumbach
Summary: This study examines the knowledge and beliefs about COVID-19 vaccination among historically marginalized populations in the San Francisco Bay Area, including Black/African American, Latinx, and Chinese American residents. The findings highlight themes of misinformation, mistrust of government and health institutions, and barriers to vaccine access, such as language and transportation. It emphasizes the importance of addressing systemic racism and involving trusted messengers from the community to eliminate barriers to vaccine access.
Article
Microbiology
Venice Servellita, Mary Kate Morris, Alicia Sotomayor-Gonzalez, Amelia S. Gliwa, Erika Torres, Noah Brazer, Alicia Zhou, Katherine T. Hernandez, Madeline Sankaran, Baolin Wang, Daniel Wong, Candace Wang, Yueyuan Zhang, Kevin R. Reyes, Dustin Glasner, Xianding Deng, Jessica Streithorst, Steve Miller, Edwin Frias, Mary Rodgers, Gavin Cloherty, John Hackett, Carl Hanson, Debra Wadford, Susan Philip, Scott Topper, Darpun Sachdev, Charles Y. Chiu
Summary: A combined analysis of SARS-CoV-2 viral load and whole-genome sequences from COVID-19 patients reveals that vaccine breakthrough infections are more commonly associated with antibody-resistant SARS-CoV-2 variants than infections in unvaccinated individuals, and that symptomatic breakthrough infections may be as efficient in spreading COVID-19 as unvaccinated infections.
NATURE MICROBIOLOGY
(2022)
Article
Urban Studies
Kaitlin F. Strange, Hug March, Mar Satorras
Summary: This study investigates the case of San Francisco as a forerunner in climate action and a city experiencing inequality. It found that San Francisco's focus in climate planning has shifted from technology and science to addressing justice concerns and resident needs. Although efforts have been made to develop climate justice plans, further research is needed to fully integrate climate justice into implementation.
Article
Multidisciplinary Sciences
Christopher J. Hernandez, Dillon Trujillo, Sofia Sicro, Joaquin Meza, Mackie Bella, Emperatriz Daza, Francisco Torres, Willi McFarland, Caitlin M. Turner, Erin C. Wilson
Summary: Trans women are shown to be at increased risk of HCV infection with age and history of injection drug use. Regular HCV screening and treatment access are recommended to be offered in trans-specific health services, communities, jails, and syringe exchange programs.
Article
Medicine, General & Internal
Caroline Cawley, Hemal K. Kanzaria, Barry Zevin, Kelly M. Doran, Margot Kushel, Maria C. Raven
Summary: During the first year of the COVID-19 pandemic, there was a significant increase in deaths among homeless individuals in San Francisco, with the majority being male. The main causes of death were acute drug toxicity and traumatic injury. COVID-19 was not listed as the primary cause of any deaths, and there was a decrease in the number of individuals receiving health services in the year prior to their death compared to previous years.
Article
Public, Environmental & Occupational Health
Ryan Whitacre, Adeola Oni-Orisan, Nadia Gaber, Carlos Martinez, Liza Buchbinder, Denise Herd, Seth Holmes
Summary: The COVID-19 pandemic has exacerbated global inequality, especially in the United States where non-white communities have suffered greater economic and social losses. The political geography of racialization has intensified the crisis, undermining public health responses.
GLOBAL PUBLIC HEALTH
(2021)
Article
Economics
Elsa Augustine, Johanna Lacoe, Steven Raphael, Alissa Skog
Summary: This study estimated the impact of referral to felony pretrial diversion programs on case outcomes and subsequent criminal justice contact. It found that referral to diversion increases the time to disposition in the current case and decreases the probability of a subsequent conviction up to five years after case arraignment. Subgroup analyses showed that the benefits of diversion are most pronounced among females, individuals under the age of 25, and those facing drug sales charges.
JOURNAL OF POLICY ANALYSIS AND MANAGEMENT
(2022)
Article
Marine & Freshwater Biology
Paul H. Hutton, Sujoy B. Roy
Summary: This study evaluates the applicability of PSS-78 in measuring salinity across the San Francisco Estuary, where salinity is influenced by a mixture of seawater, riverine inflows, and agricultural return flows. The study finds that PSS-78 is valid in waters dominated by seawater intrusion and the Sacramento River, but underestimates salinity in waters influenced by the San Joaquin River and agricultural return flows. Therefore, the study suggests appropriate corrections to PSS-78 for accurate salinity estimation in these drainage-influenced waters.
ESTUARINE COASTAL AND SHELF SCIENCE
(2023)
Article
Multidisciplinary Sciences
Samuel M. Bashevkin, Rosemary Hartman, Madison Thomas, Arthur Barros, Christina E. Burdi, April Hennessy, Trishelle Tempel, Karen Kayfetz
Summary: This article presents the longest available dataset of estuarine zooplankton abundance worldwide, which includes data from five monitoring programs, over 300 locations, and over two billion sampled organisms. These data can be used to study issues related to species invasions, flows, fish diets and population dynamics, zooplankton population dynamics, and community ecology.
Article
Environmental Sciences
Esther M. John, Jocelyn Koo, Sue A. Ingles, Theresa H. Keegan, Jenny T. Nguyen, Catherine Thomsen, Mary Beth Terry, Regina M. Santella, Khue Nguyen, Beizhan Yan
Summary: Urinary PAH exposure was found to be widespread in girls aged 6-16 years, with concentrations varying by age, race/ethnicity, body mass index percentile, as well as outdoor, indoor, and dietary sources of exposure.
ENVIRONMENTAL RESEARCH
(2022)
Article
Multidisciplinary Sciences
Isobel Routledge, Adrienne Epstein, Saki Takahashi, Owen Janson, Jill Hakim, Elias Duarte, Keirstinne Turcios, Joanna Vinden, Kirk Sujishi, Jesus Rangel, Marcelina Coh, Lee Besana, Wai-Kit Ho, Ching-Ying Oon, Chui Mei Ong, Cassandra Yun, Kara Lynch, Alan H. B. Wu, Wesley Wu, William Karlon, Edward Thornborrow, Michael J. Peluso, Timothy J. Henrich, John E. Pak, Jessica Briggs, Bryan Greenhouse, Isabel Rodriguez-Barraquer
Summary: SCALE-IT is a new platform for serosurveillance that utilizes algorithmic sampling of electronic health records to estimate the seroprevalence of SARS-CoV-2 in San Francisco. The study suggests that this method can identify important heterogeneities by neighborhood, homelessness status, and race/ethnicity.
NATURE COMMUNICATIONS
(2021)
Article
Allergy
Alexander J. Strzalkowski, Kirsi M. Jarvinen, Brianne Schmidt, Bridget E. Young
Summary: The protein and carbohydrate composition of infant formula purchased in the US was analyzed in this study. The results showed that US infants are exposed to high levels of non-lactose carbohydrates and hypoallergenic formula, posing a potential nutritional health risk.
CLINICAL AND EXPERIMENTAL ALLERGY
(2022)
Article
Agriculture, Dairy & Animal Science
Cassie J. Cain, Kimberly A. Woodruff, David R. Smith
Summary: This study aimed to investigate whether certain phenotypic characteristics of shelter dogs can predict their likelihood of being euthanized, and the results suggest that these characteristics are indeed associated with the risk of euthanasia in shelters.
Article
Meteorology & Atmospheric Sciences
Stephanie May, Andrew J. J. Oliphant
Summary: Mobile bicycle transects were conducted to study the effects of urban green spaces on thermal comfort in San Francisco. Results showed that Golden Gate Park had lower temperatures than nearby residential areas, with temperature differences ranging from 0.9°C to 3.7°C. The park's vegetation, especially dense trees, played a key role in providing shade and evaporative cooling, leading to the park's cooling effect.
THEORETICAL AND APPLIED CLIMATOLOGY
(2023)
Article
Engineering, Civil
Floriana Petrone, Norman Abrahamson, David McCallen, Arben Pitarka, Arthur Rodgers
Summary: This study evaluates the first EQSIM ground-motion simulations generated for the San Francisco Bay Area and proposes a methodology for their evaluation. The objective is to enhance confidence in the simulated motions and offer physics-based interpretations to improve simulation models, while also exploring the implications of using simulated ground motions for site-specific structural assessments.
EARTHQUAKE ENGINEERING & STRUCTURAL DYNAMICS
(2021)
Letter
Dermatology
Leah Shin, Shahin Shahsavari, Jennifer Laborada, Claudia Lee, Jacob Pontoppidan Thyssen, Jashin J. Wu
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Letter
Dermatology
I. Vittrup, A. G. Frostrup, S. T. Gren, S. F. Thomsen, J. J. Wu, P. Schmid-Grendelmeier, J. -T. Maul, A. Egeberg, J. P. Thyssen
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Letter
Dermatology
Caroline Meyer Olesen, Yasemin Topal Yueksel, Claus Zachariae, Tamara Theresia Lund, Tove Agner, Tonny Studsgaard Petersen, Jacob Pontoppidan Thyssen
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Dermatology
Sandra F. Nilsson, Zarqa Ali, Thomas M. Laursen, Jacob P. Thyssen, Alexander Egeberg, Merete Nordentoft, Carsten Hjorthoj, Simon F. Thomsen
Summary: This study examines the association between homelessness and diagnosed skin conditions, prescribed medication, and type of consultation. The findings suggest that homelessness is associated with an increased risk of skin conditions, but a lower occurrence of skin cancer diagnosis. Individuals experiencing homelessness have different diagnostic and medical patterns for skin disorders compared to those not experiencing homelessness.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Dermatology
Anna S. Quaade, Xing Wang, Julie B. K. Solberg, Nina H. Ulrich, Benjamin D. McCauley, Jacob P. Thyssen, Christine Becker, Jeanne D. Johansen
Summary: This study characterized the plasma inflammatory signature of chronic hand eczema (CHE) and found that severe CHE without a history of atopic dermatitis (AD) is associated with systemic Th2-driven inflammation. Targeting type 2 inflammation could be effective in treating various subtypes of CHE.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Dermatology
Thomas Bieber, Jacob P. Thyssen, Alan D. Irvine, Yuichiro Tsunemi, Yun-Fei Chen, Luna Sun, Andrea Schloebe, Elisabeth Riedl, Michael J. Cork
Summary: Early improvement in signs and symptoms during treatment with baricitinib can predict clinical response at week 16, offering guidance for dermatologists in selecting treatment strategies for patients with moderate-to-severe AD.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2023)
Article
Dermatology
Julie B. K. Solberg, Anna S. Quaade, Lylia Drici, Karolina Sulek, Nina H. Ulrich, Marianne B. Lovendorf, Jacob P. Thyssen, Matthias Mann, Beatrice Dyring-Andersen, Jeanne D. Johansen
Summary: The noninvasive tape strip method in combination with liquid chromatography-mass spectrometry proteomics can be used to analyze skin protein expression in patients with hand eczema (HE), and has potential for subtype differentiation and biomarker discovery. HE lesional samples exhibit increased expression of immune-related markers and decreased expression of structural barrier proteins compared to healthy skin. The subtype differences in HE are restricted to the lesional areas and include increased expression of skin barrier-related proteins independently of concurrent atopic dermatitis.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2023)
Article
Dermatology
David Thein, Nana A. L. Roseno, Julia-Tatjana Maul, Jashin J. Wu, Lone Skov, Lars Erik Bryld, Mads K. Rasmussen, Kawa Khaled Ajgeiy, Simon Francis Thomsen, Jacob P. Thyssen, Alexander Egeberg
Summary: The real-world effectiveness of biologics in treating psoriasis was examined using a nationwide registry. The results showed that the risk of discontinuation or off-label dose escalation was lower for secukinumab compared to ustekinumab, but higher for adalimumab. However, the risk of discontinuation was higher for both secukinumab and adalimumab. For patients who were bio-naive, the risk of discontinuation was comparable between secukinumab and ustekinumab.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2023)
Article
Dermatology
J. P. Thyssen, D. Thaci, T. Bieber, M. Gooderham, M. de Bruin-Weller, W. Soong, K. Kabashima, S. Barbarot, P. C. Luna, J. Xu, X. Hu, Y. Liu, E. M. Raymundo, B. M. Calimlim, C. Nduaka, A. Gamelli, E. L. Simpson
Summary: This study evaluated the efficacy of oral Janus kinase inhibitor upadacitinib in subgroups of patients with moderate-to-severe atopic dermatitis (AD). The results showed that upadacitinib consistently improved skin condition and itch in these subgroups, regardless of age, sex, race, disease severity, body surface area involvement, past treatment history, etc. These findings support upadacitinib as a suitable treatment option for a variety of AD patients.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Letter
Dermatology
Brandon Smith, Priya Engel, Michael R. R. Collier, Shivali Devjani, Jacob P. P. Thyssen, Jashin J. J. Wu
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Dermatology
Andreas Wollenberg, Jacob P. Thyssen, Thomas Bieber, Gary Chan, Urs Kerkmann
Summary: The PRAC of the EMA has reevaluated the benefit-risk balance of oral JAKi and recommended their use only if no suitable alternatives are available. They should be used with caution in patients with certain risk factors, and the European Commission has made a final decision in March 2023.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Endocrinology & Metabolism
Anna Korsgaard Berg, Annemarie Cecilie Grauslund, Fiona Sorensen, Steffen Ullitz Thorsen, Jacob P. Thyssen, Claus Zachariae, Jannet Svensson
Summary: Diabetes devices used for insulin delivery and blood glucose measurement often cause skin problems, such as eczema and wounds. This study aimed to provide evidence-based information on the efficacy of a basic skin care program in preventing these skin problems. The results showed that the program partially prevented diabetes device-induced skin reactions, but additional preventive strategies are needed for optimized prevention.
Article
Dermatology
V. W. Nielsen, C. B. Johansen, T. Todberg, L. Skov, C. V. Nissen, R. Dodge, A. Egeberg, J. P. Thyssen, S. F. Thomsen
Summary: This study evaluated a value-based healthcare model for psoriasis patients, remunerating treatment based on patient reported outcomes and successfully predicting expected outcomes to incentivize over-performance.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Letter
Dermatology
Robert Bissonnette, Eric Simpson, Lawrence F. Eichenfield, Emma Guttman-Yassky, Jonathan I. Silverberg, Lisa A. Beck, Lorena Mija, Jacob P. Thyssen, Thomas Bieber, Kenji Kabashima, Elaine Siegfried, Georg Stingl, Peter van de Kerkhof, Gil Yosipovitch, Carle Paul, Amy S. Paller
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Allergy
Signe Kjeldgaard Jensen, Mathias Elsner Melgaard, Casper-Emil Tingskov Pedersen, Luo Yang, Nilo Vahman, Jacob P. Thyssen, Ann-Marie M. Schoos, Jakob Stokholm, Hans Bisgaard, Bo Chawes, Klaus Bonnelykke
Summary: Blood eosinophil count at 18 months was not associated with current wheezing/asthma or atopic dermatitis, while blood eosinophil count at age 6 years was associated with increased occurrence of current wheezing/asthma, atopic dermatitis, and allergic rhinitis. Blood eosinophil count at 18 months did not predict persistence or development of recurrent wheeze/asthma or atopic dermatitis at age 6 years.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)