Article
Environmental Sciences
Qiong Huang, Siqi Li, Jinfa Wan, Wenbin Nan, Baimei He
Summary: This study found that exposure to ethylene oxide (EO) is associated with an increased prevalence of chronic obstructive pulmonary disease (COPD). There is a J-shaped relationship between EO exposure and COPD risk, and inflammation plays a key role in the effects of EO exposure on COPD.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Psychiatry
Lucy Riglin, Rachel Blakey, Kate Langley, Ajay K. Thapar, Sharifah Shameem Agha, George Davey Smith, Evie Stergiakouli, Anita Thapar
Summary: The study found that asking adults to recall specific symptoms may be more accurate than asking about the age at which symptoms started, while limitations to retrospective recall contribute to the debate on the validity of ADHD age-at-onset assessment.
BRITISH JOURNAL OF PSYCHIATRY
(2022)
Article
Obstetrics & Gynecology
Mandy S. Hall, Nicole M. Talge, Kristen Upson
Summary: This study suggests that exposure to the toxic metal cadmium is associated with an increased prevalence of endometriosis among a nationally representative sample of the US population. Previous epidemiological studies on cadmium and endometriosis have yielded mixed results. Using data from the National Health and Nutrition Examination Survey, this cross-sectional study found that higher urinary cadmium concentrations were associated with a higher prevalence of endometriosis.
HUMAN REPRODUCTION
(2023)
Article
Clinical Neurology
Gauruv Bose, Brian C. Healy, Christian Barro, Bonnie Glanz, Hrishikesh A. Lokhande, Mariann Polgar-Turcsanyi, Charles R. G. Guttmann, Rohit Bakshi, Howard L. Weiner, Tanuja Chitnis
Summary: For patients with multiple sclerosis (MS) who have a disease duration of more than 10 years, an earlier age at onset is associated with worse outcomes at age 50, including higher disability, increased risk of secondary-progressive MS, more brain lesions, worse brain parenchymal fraction, and higher likelihood of unemployment due to MS.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2022)
Review
Neurosciences
Stacey D. Espinet, Gemma Graziosi, Maggie E. Toplak, Jacqueline Hesson, Priyanka Minhas
Summary: ADHD is a common neurodevelopmental disorder, and this study aims to clarify its epidemiology in Canada. The results show that the prevalence of ADHD in Canada is similar to global estimates, but varies across provinces, possibly due to differences in the availability of healthcare professionals for diagnosis and medication prescribing. Further research is needed to gain a more comprehensive understanding of ADHD in Canada.
Article
Critical Care Medicine
Mohammad Alrawashdeh, Michael Klompas, Steven Q. Simpson, Sameer S. Kadri, Russell Poland, Jeffrey S. Guy, Jonathan B. Perlin, Chanu Rhee
Summary: The study aims to investigate the proportion of previously healthy patients among adults hospitalized with community-onset sepsis and compare their outcomes with those of patients with comorbidities. Retrospective analysis was conducted on adult patients with community-onset sepsis in 373 US hospitals between 2009 and 2015. The majority of patients with sepsis had comorbidities, but previously healthy patients had higher short-term mortality rates compared to patients with comorbidities.
Article
Psychology, Developmental
Paolo Valsecchi, Gabriele Nibbio, Jennifer Rosa, Elena Tamussi, Cesare Turrina, Emilio Sacchetti, Antonio Vita
Summary: ADHD remains largely underdiagnosed in Europe, including Italy. A study in Italian outpatients found a prevalence rate of 12.8% positive for ADHD symptoms, with 6.9% meeting criteria for Adult ADHD. Significant clinical and demographic differences were found between ADHD positive and negative groups.
JOURNAL OF ATTENTION DISORDERS
(2021)
Article
Endocrinology & Metabolism
Guangdong Cheng, Mengmeng Wang, Hao Sun, Jingjiang Lai, Yukun Feng, Hongjin Liu, Yuwang Shang, Yuan Zhao, Bingli Zuo, Youhua Lu
Summary: Age at menopause is negatively associated with the prevalence of cervical and ovarian cancers, and the earlier the age at menopause, the greater the risk of developing gynecological cancers.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Clinical Neurology
April C. E. van Gennip, Thomas T. van Sloten, Aurore Fayosse, Severine Sabia, Archana Singh-Manoux
Summary: This study suggests that developing cardiovascular disease in midlife increases the risk of dementia in later life, but maintaining a healthy lifestyle following a CVD diagnosis can mitigate this risk.
ALZHEIMERS & DEMENTIA
(2023)
Article
Cardiac & Cardiovascular Systems
Weijian Li, Wei Fang, Zegui Huang, Xianxuan Wang, Zefeng Cai, Guanzhi Chen, Weiqiang Wu, Zhichao Chen, Shouling Wu, Youren Chen
Summary: Younger age at onset of overweight across adulthood is associated with significantly increased risk of hypertension, with the highest relative risk among participants with onset of overweight at 18-39 years of age.
Article
Nutrition & Dietetics
Jingxin Zhou, Lixia Lou, Kai Jin, Juan Ye
Summary: This study found that adherence to the healthy eating pattern, HEI-2015, is associated with a lower risk of age-related cataracts.
Article
Environmental Sciences
Anne E. Nigra, Katherine A. Moon, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: The study found an association between urinary arsenic levels and heart disease mortality, especially for low-to moderate-levels of iAs exposure. Despite a limited number of events and a relatively short follow-up time, the flexible dose-response models demonstrated significant associations.
ENVIRONMENTAL RESEARCH
(2021)
Article
Medicine, General & Internal
Yue Wen, Tingting Liu, Shengxu Li, Renrong Gong, Changwei Li
Summary: Over the past 15 years, the prevalence of central obesity has increased in the US adult population, while the prevalence of metabolically healthy obesity among those with central obesity has remained relatively stable. The prevalence of metabolically healthy obesity has significantly increased among women, and factors such as female gender, younger age, being Hispanic or non-Hispanic black, and higher education level are significantly associated with a higher prevalence of metabolically healthy obesity.
Article
Oncology
Caroline Himbert, Jane C. Figueiredo, David Shibata, Jennifer Ose, Tengda Lin, Lyen C. Huang, Anita R. Peoples, Courtney L. Scaife, Bartley Pickron, Laura Lambert, Jessica N. Cohan, Mary Bronner, Seth Felder, Julian Sanchez, Sophie Dessureault, Domenico Coppola, David M. Hoffman, Yosef F. Nasseri, Robert W. Decker, Karen Zaghiyan, Zuri A. Murrell, Andrew Hendifar, Jun Gong, Eiman Firoozmand, Alexandra Gangi, Beth A. Moore, Kyle G. Cologne, Maryliza S. El-Masry, Nathan Hinkle, Justin Monroe, Matthew Mutch, Cory Bernadt, Deyali Chatterjee, Mika Sinanan, Stacey A. Cohen, Ulrike Wallin, William M. Grady, Paul D. Lampe, Deepti Reddi, Mukta Krane, Alessandro Fichera, Ravi Moonka, Esther Herpel, Peter Schirmacher, Matthias Kloor, Magnus Von Knebel-Doeberitz, Johanna Nattenmueller, Hans-Ulrich Kauczor, Eric Swanson, Jolanta Jedrzkiewicz, Stephanie L. Schmit, Biljana Gigic, Alexis B. Ulrich, Adetunji T. Toriola, Erin M. Siegel, Christopher Li, Cornelia M. Ulrich, Sheetal Hardikar
Summary: The study highlights the increasing number of cases of colorectal cancer in individuals under 50 years old in the Western world, with reasons remaining unclear. By comparing characteristics of patients, the study aims to identify potential risk factors and clinical characteristics of colorectal cancer patients diagnosed under the age of 50 years. Patients with early-onset colorectal cancer were more likely to be diagnosed with advanced stage disease, to have received systemic treatments regardless of stage at diagnosis, and were less likely to be ever smokers or overweight.
Article
Endocrinology & Metabolism
Jaewon Lee, Kyae Hyung Kim, Joseph C. Ahn, Jihoon Andrew Kim, Gyeongsil Lee, Joung Sik Son, Soo Jung Choi, Yun Hwan Oh, Sang Min Park
Summary: As depressive symptoms worsen, the prevalence and awareness of diabetes increase, but there are inadequacies in treatment and control, highlighting the unmet needs for multidisciplinary care for patients with comorbid depression and DM.
BMJ OPEN DIABETES RESEARCH & CARE
(2021)
Article
Psychology, Developmental
Rebecca Hommer, Tarannum Lateef, Jian-Ping He, Kathleen Merikangas
Summary: The objective of this study was to examine the association between headache and mental disorders in American youth. The findings showed that headache was prevalent among youth, especially females. Youth with headache were more likely to meet criteria for DSM-IV mental disorders. Migraine, particularly with aura, was associated with depression and anxiety, as well as multiple classes of disorders.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Article
Clinical Neurology
Emma K. Stapp, Diana Paksarian, Jian-Ping He, Jennifer Glaus, Kevin P. Conway, Kathleen R. Merikangas
Summary: This study examined the association between mood and anxiety syndromes with physical conditions, revealing differential associations of specific mood-anxiety profiles with headaches, heart problems, and back/neck pain. Subtyping depression and anxiety may facilitate research and intervention work in multimorbidity.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Materials Science, Biomaterials
Xing Qin, Limei Qin, Jianping He, Qinghua Wang, Yongsheng Li, Dechao Niu
Summary: This study presents a confined crosslink protocol to prepare an intelligent hybrid drug delivery system for auto-fluorescent monitoring, protonation-induced retention, and precise drug release. The system changes size depending on pH levels, contributing to high-efficiency chemotherapy, making it a new method for constructing smart, acid-responsive, and fluorescent-guided drug delivery systems for efficient and safe tumor chemotherapy.
BIOMATERIALS SCIENCE
(2022)
Article
Multidisciplinary Sciences
Jinyan Lin, Nannan Lin, Qi Yang, Zhiqiang Hao, Xiaoqi Sun, Jianping He, Jingang Li
Summary: Gansu zokor adapts to hypoxia environment by enhancing fructose and lipid metabolism.
CHIANG MAI JOURNAL OF SCIENCE
(2022)
Article
Engineering, Civil
Xu Lei, Jianping He, Linqian Fan, Guiping Wang
Summary: This paper proposes a nondissipative equalization structure for addressing the inconsistency issue among series-connected LIB cells and compares it with three other equalization circuits. The state of charge (SOC) is estimated using the second-order RC model of the LIB and the adaptive unscented Kalman filter (AUKF) algorithm. The adaptive fuzzy neural network (AFNN) algorithm is utilized for effective equalization. The experiment results demonstrate that the proposed equalization structure significantly accelerates the equalization process and reduces the equalization loss compared to the other three equalization circuits.
JOURNAL OF ADVANCED TRANSPORTATION
(2022)
Article
Computer Science, Information Systems
Fangfang Liu, Mengmeng Xiao, Yongkai Ning, Shaoyuan Zhou, Jianping He, Yanxia Lin, Zhiyong Zhang
Summary: Researchers have developed a gate assistant technology to accelerate the recovery of gas sensors and promote their practical application, by applying voltage to speed up the desorption of gas molecules in semiconducting carbon nanotube films. This technology, combined with a modified concentration calculation method, has resulted in highly reproducible and rapid detection systems for hydrogen gas.
SCIENCE CHINA-INFORMATION SCIENCES
(2022)
Article
Energy & Fuels
Manman Zhao, Xianli Huang, Dongmei Zhuang, Lei Sheng, Xin Xie, Min Cao, Junjie Pan, Haiyun Fan, Jianping He
Summary: By preparing a composite current collector with a porous nanospheres structure (Cu3N-NS/Cu), this study improves the cyclic reversibility and lithium deposition morphology of lithium metal batteries. The composite collector has a higher specific surface area, which benefits the diffusion of lithium ions and reduces the local current density of the electrode.
JOURNAL OF ENERGY STORAGE
(2022)
Article
Cardiac & Cardiovascular Systems
Jinyan Lin, Qi Yang, Juanjuan Guo, Meng Li, Zhiqiang Hao, Jianping He, Jingang Li
Summary: The gut microbiota of the Gansu zokor changes under hypoxia, with an increased contribution of Ileibacterium to carbohydrate metabolism. The liver of the Gansu zokor enhances carbohydrate metabolism under short-term hypoxia but is suppressed under long-term hypoxia. However, the liver maintains enhanced fructose-driven metabolism under all hypoxia conditions.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Hong Chen, Mengmeng Xiao, Jianping He, Yang Zhang, Yuqi Liang, Haiyang Liu, Zhiyong Zhang
Summary: Nanomaterial-based biosensors show promise in highly sensitive and selective detection of Alzheimer's disease blood biomarkers, overcoming challenges posed by the complex serum environment and low abundance of these biomarkers.
Article
Computer Science, Artificial Intelligence
Shudong Zhang, Haichang Gao, Chao Shu, Xiwen Cao, Yunyi Zhou, Jianping He
Summary: Deep neural networks are vulnerable to adversarial attacks and this paper proposes a query efficient gradient-free attack method, which achieves high attack success rates and can also attack state-of-the-art defense methods.
Article
Oncology
Yaqin Zhao, Jianping He, Xia Liu, Cheng Yi, Lei Sun, Hong Zhu
Summary: A novel TRAIL mutant, MuR5S4-TR, was constructed with CPP-like and Smac-like structure, which significantly enhanced the antitumor effects of TRAIL in multiple tumor cell lines. The preliminary study suggests that MuR5S4-TR could be a more efficient form of TRAIL for cancer therapy.
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Meng Li, Yifan Peng, Wenjun Chen, Yongjiao Gao, Maohong Yang, Jingang Li, Jianping He
Summary: The study found that Gansu zokor increases the activity and protein content of antioxidant enzymes such as HO-1 and NQO-1 by up regulating Nrf2 gene expression under hypoxic conditions. Furthermore, Gansu zokor exhibits different regulation of Nrf2 signaling and expression of downstream antioxidant enzymes under different oxygen concentrations.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2023)
Article
Psychology, Multidisciplinary
Yixuan Liu, Jiayu Zhu, Jianping He
Summary: As modernization advances, social media has become an integral part of people's daily lives and an extension of real social interactions. The relationship between selfie behavior, as an important practice among youth on social media, and social anxiety needs further exploration. This study aims to investigate the current situation of selfie behavior, body image, and social anxiety among young people in China.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Yuqi Liang, Mengmeng Xiao, Jing Xie, Jiahao Li, Yuyan Zhang, Haiyang Liu, Yang Zhang, Jianping He, Guojun Zhang, Nan Wei, Lian-Mao Peng, Yuehua Ke, Zhi-Yong Zhang
Summary: A multi-functionalized FG-CNT FET biosensor is developed for rapid detection of SARS-CoV-2 virus antigen and RNA. The aptamers functionalized sensors can detect antigens from unprocessed samples within 1 min, while the FG-CNT FET biosensor can detect long chain RNA without amplification down to single virus level within 1 min. The device, consisting of sensor chips and a portable terminal, can accurately differentiate COVID-19 patients from healthy individuals with high agreement percentage.
Article
Psychology, Clinical
Tomoya Hirota, Diana Paksarian, Jian-Ping He, Sachiko Inoue, Emma K. Stapp, Anna Van Meter, Kathleen R. Merikangas
Summary: This study examined the associations between various social capital constructs and adolescent mental disorders, severity of impairment, and comorbidity. It found that supportive friendships, family cohesion, school bonding, and extracurricular participation were consistently associated with lower odds of mental disorders in adolescents. The findings suggest that improving social capital, especially in areas like friendships, family, and school, could help prevent and treat adolescent mental disorders and comorbidity.
JOURNAL OF CLINICAL CHILD AND ADOLESCENT PSYCHOLOGY
(2022)
