Review
Oncology
Gang Li, Hongxiang Ji, Jiang Li, Linfeng Xiao, Zhan Chen
Summary: This meta-analysis found that mastectomy with immediate reconstruction does not affect postoperative survival rates in breast cancer patients who have completed neoadjuvant chemotherapy. However, it may slightly increase the risk of short-term surgical complications.
FRONTIERS IN ONCOLOGY
(2023)
Review
Oncology
Seok Kyung Kang, Dong Il Kim, Seungju Lee, Youn Joo Jung, Jung Yeol Seo, Su Bong Nam, Kyoungjune Pak, Seokwon Lee, Hyun Yul Kim
Summary: A systematic review and meta-analysis of breast reconstruction after mastectomy showed similar event-free survival (EFS) and breast cancer-specific survival (BCSS) rates compared to mastectomy alone, but better overall survival (OS). Breast reconstruction is a feasible and safe treatment option for breast cancer patients.
TRANSLATIONAL CANCER RESEARCH
(2023)
Review
Oncology
Claudia A. Bargon, Danny A. Young-Afat, Mehmet Ikinci, Assa Braakenburg, Hinne A. Rakhorst, Marc A. M. Mureau, Helena M. Verkooijen, Annemiek Doeksen
Summary: The oncological safety of different types and timings of postmastectomy breast reconstruction (PMBR) remains controversial. This study found that delayed autologous PMBR leads to similar (loco)regional recurrence rates as immediate autologous PMBR. Current evidence suggests that oncological concerns should not be a reason to withhold patients from certain reconstructive timings or techniques, and patients should be offered all technically qualified reconstructive options equally.
Article
Oncology
Yanni Song, Shanshan Sun, Dalin Li, Jiguang Han, Ming Niu, Sai Luo, Haiqian Xu, Rui Huang, Sihang Zhang, Yang Wu, Qiqi Wu, Jing Xiong, Lijun Hao
Summary: Immediate reconstruction (IR) improves aesthetic satisfaction, psychosocial, and sexual well-being for breast cancer patients with T <= 3 cm. For patients with T > 3 cm invasive breast cancer, total mastectomy (TM) is superior to IR as it predicts a better 5-year disease-free survival (DFS).
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2021)
Article
Health Care Sciences & Services
Lorenzo Scardina, Alba Di Leone, Ersilia Biondi, Beatrice Carnassale, Alejandro Martin Sanchez, Sabatino D'Archi, Antonio Franco, Francesca Moschella, Stefano Magno, Daniela Terribile, Damiano Gentile, Alessandra Fabi, Anna D'Angelo, Liliana Barone Adesi, Giuseppe Visconti, Marzia Salgarello, Riccardo Masetti, Gianluca Franceschini
Summary: This study compared the outcomes of submuscular versus prepectoral implant placement in conservative mastectomy with immediate prosthetic breast reconstruction. The results showed that prepectoral implant placement is a safe and effective alternative with shorter operative time and fewer complications related to manipulation of the pectoralis major muscle.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Oncology
Basilio Duenas-Rodriguez, Joaquin Navarro-Cecilia, Carolina Luque-Lopez, Belen Sanchez-Andujar, Juan Arsenio Garcelan-Trigo, Maria Jesus Ramirez-Exposito, Jose Manuel Martinez-Martos
Summary: This study evaluated postoperative complications, aesthetic results, and satisfaction outcomes in patients with breast cancer who underwent skin-sparing or nipple-sparing mastectomy with immediate prosthetic reconstruction. The use of a biological mesh during reconstruction resulted in lower implant loss and higher satisfaction rates.
Article
Oncology
Alessandro Fancellu, Giulia Deiana, Valeria Sanna, Corrado Rubino, Antonio Cossu, Pietrina Cottu, Giuliana Giuliani, Lisa Sant, Giuseppe Norcia, Alberto Porcu
Summary: The use of immediate breast reconstruction (IBR) after mastectomy has been increasing in all age groups. This study evaluated the age-specific trend of IBR and its impact on work organization at an Italian Breast Unit. The results showed that rates of mastectomy + IBR increased over the years, especially among older women. Furthermore, mastectomy + IBR resulted in longer operative times and hospital stay compared to mastectomy alone.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Review
Oncology
Matteo Lambertini, Eva Blondeaux, Marco Bruzzone, Marta Perachino, Richard A. Anderson, Evandro de Azambuja, Philip D. Poorvu, Hee Jeong Kim, Cynthia Villarreal-Garza, Barbara Pistilli, Ines Vaz-Luis, Cristina Saura, Kathryn J. Ruddy, Maria Alice Franzoi, Chiara Sertoli, Marcello Ceppi, Hatem A. Azim, Frederic Amant, Isabelle Demeestere, Lucia Del Mastro, Ann H. Partridge, Olivia Pagani, Fedro A. Peccatori
Summary: This study found that breast cancer survivors are less likely to have a subsequent pregnancy compared to the general population, and they face higher risks during pregnancy, especially among those who have received chemotherapy. However, compared to breast cancer patients without subsequent pregnancy, those who become pregnant have better disease-free survival and overall survival rates.
JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Dermatology
Chao Zhang, Juanjuan Li, Lin Wang, Siyu Sun, Chunchun Chen
Summary: Using meta-analysis, this study evaluated the effect of neoadjuvant chemotherapy (NACT) on wound infection during immediate breast reconstruction (IBR) after breast cancer. The analysis of 14 studies involving 3401 patients showed that NACT did not significantly increase the risk of surgical site infection during IBR. However, further randomized controlled trials are needed to confirm the safety of IBR in patients receiving neoadjuvant chemotherapy.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Surgery
Marloes E. Clarijs, Noelle J. M. C. Vrancken Peeters, Sophie A. F. van Dongen, Linetta B. Koppert, Andrea L. Pusic, Marc A. M. Mureau, Bianca F. M. Rijken
Summary: This systematic review compared patient-reported outcomes (PROs) and complication rates after nipple-sparing mastectomy (NSM) and skin-sparing mastectomy (SSM). The study found that NSM resulted in higher scores in sexual and psychosocial well-being, with no differences in overall complication rates between the two groups. Therefore, the decision for NSM or SSM should be made on an individual basis, considering factors such as patient preferences and safety.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Oncology
Susie X. Sun, Zhigang Duan, Henry M. Kuerer, Sarah M. DeSnyder, Carrie Cunningham, Hui Zhao, Sharon H. Giordano
Summary: This study examined the rate and risk factors for emergency department (ED) visits following outpatient breast cancer surgery. The findings showed that a substantial number of patients returned to the ED within 30 days of surgery, but most did not require hospital admission. Factors such as race, income, marital status, cancer stage, and comorbidity score were found to be predictors of ED visits.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Susie X. Sun, Zhigang Duan, Henry M. Kuerer, Sarah M. DeSnyder, Carrie Cunningham, Hui Zhao, Sharon H. Giordano
Summary: This study aimed to investigate the rate and risk factors of emergency department (ED) visits following outpatient breast cancer surgery. The study found that although a substantial number of patients returned to the ED, most did not require hospital admission, indicating that a large proportion of these visits could have been avoided. Several clinical and socioeconomic predictors of postoperative ED visits were identified, which will aid in the development of patient risk profiling tools.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Medicine, General & Internal
Qiuming Liu, Weifeng Li, Xiaobo Wu, Liang Xu, Pinghua Hu, Yali Cao
Summary: This study reviewed 43 breast cancer patients who underwent immediate breast reconstruction using the latissimus dorsi myocutaneous flap. The reconstructed breasts showed natural shape, good symmetry, and hidden postoperative scars, indicating a relatively good aesthetic effect. The success of the procedure depends on the incision design, surgical skill, and correct postoperative treatment.
Article
Health Care Sciences & Services
Tomas Ventruba, Michal Jeseta, Lubos Minar, Jindrich Vomela, Dagmar Brancikova, Jana Zakova, Pavel Ventruba
Summary: This study investigates women's awareness of immediate breast reconstruction (IBR) in relation to BRCA mutations and breast cancer. The results show that most women only learned about IBR before their surgical procedure and all of them wished to maintain body integrity.
Article
Surgery
Emma J. M. Grigor, Michael J. Stein, Angel Arnaout, Bahareh Ghaedi, Tim Ramsay, Jing Zhang
Summary: This study aimed to evaluate the oncological safety of MIBR in TNBC patients compared to non-TNBC patients. The results of propensity score-matching analysis showed no significant differences in various aspects, including delays to first radiochemotherapy, postoperative complication rates, and locoregional recurrence rates, between TNBC and non-TNBC patients. Furthermore, there was no significant difference in disease-free interval between TNBC and non-TNBC patients.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
