Article
Biology
Melissa J. Polonenko, Ross K. Maddox
Summary: The study introduced a new method that pairs re-synthesized 'peaky' speech with deconvolution analysis of electroencephalography recordings, quickly yielding robust responses involving distinct subcortical structures from the auditory nerve to rostral brainstem in adults with normal hearing. This peaky speech method shows promise as a tool for investigating speech encoding and processing, as well as for clinical applications.
Article
Acoustics
Naomi F. Bramhall
Summary: Even though imaging has largely replaced ABR in clinical practice for detecting retrocochlear disorders, the discovery of cochlear synaptopathy has brought ABR back into focus as a measure of auditory function. Studies in animal models suggest a strong correlation between the amplitude of the first wave of ABR and synaptic integrity, leading to ongoing research on using ABR as a metric for synaptopathy in humans.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2021)
Article
Medicine, General & Internal
Gary Rance, Julien Zanin, Alice Maier, Donella Chisari, Kristina M. Haebich, Kathryn N. North, Gabriel Dabscheck, Marc L. Seal, Martin B. Delatycki, Jonathan M. Payne
Summary: This study found that 25% of NF1 patients had auditory neural dysfunction and 32% had clinically abnormal speech perception in background noise. Analysis of diffusion-weighted MRI data showed significantly lower apparent fiber density within the ascending auditory brainstem pathways in NF1 patients. These findings could represent new neurobiological and clinical features of NF1.
Article
Acoustics
Hsuan Huang, Yu-Fu Chen, Chien-Yeh Hsu, Yen-Fu Cheng, Tzong-Hann Yang
Summary: The study aimed to establish the best cochlear-neural delay model for chirp design to maximize auditory brainstem response (ABR) and compared ABRs produced by different stimuli. The results showed that the DB-Chirp generated larger wave V than the LS-Chirp at 45 dB normal hearing level (nHL), with potential clinical applications in cochlear synaptopathy assessment and hearing sensitivity estimation.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2022)
Article
Clinical Neurology
Laura Jacxsens, Joke De Pauw, Emilie Cardon, Annemarie van der Wal, Laure Jacquemin, Annick Gilles, Sarah Michiels, Vincent Van Rompaey, Marc J. W. Lammers, Willem De Hertogh
Summary: This systematic review found changes at the brainstem level in tinnitus patients, particularly prolonged latency of auditory brainstem response (ABR), which may be related to high frequency sensorineural hearing loss or other modulating factors. The changes in middle-latency AEPs are still inconclusive.
FRONTIERS IN NEUROLOGY
(2022)
Article
Audiology & Speech-Language Pathology
Sarah Hennessy, Wendy J. Mack, Assal Habibi
Summary: Musicians demonstrate superior speech-in-noise abilities compared to non-musicians, which is not influenced by age, IQ, or speech task parameters. These effects may be attributed to changes due to music training or inherent auditory advantages in musicianship.
Article
Neurosciences
Dania Rishiq, Ashley Harkrider, Cary Springer, Mark Hedrick
Summary: The study compared speech-evoked auditory brainstem responses (ABR) with click-evoked ABR in multiple sclerosis (MS) patients and controls, finding that speech-evoked ABR was more sensitive to MS-related changes and could potentially be a more effective clinical tool. Group differences were observed in peak amplitudes, latency, and response correlations, indicating potential for speech-evoked ABR to highlight neural synchrony loss in MS.
NEUROSCIENCE LETTERS
(2021)
Article
Acoustics
Jason Mulsow, James J. Finneran, Dorian S. Houser, Robert F. Burkard, Madelyn G. Strahan, Ryan Jones
Summary: Studies on dolphin auditory brainstem response (ABR) have shown that the response to sound offset includes contributions from at least two distinct responses, with one possibly arising from activation of neural units shifted basally relative to stimulus frequency, and the other representing a true offset response from afferent centers further up the auditory pathway.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2021)
Article
Neurosciences
Curtis J. Billings, Brandon M. Madsen, Leslie D. Grush, Tess K. Koerner, Garnett P. McMillan, William J. Bologna
Summary: In this study, we developed and tested a series of complex electrophysiological paradigms to evoke the auditory P3 response. The results showed that background noise had a significant impact on auditory evoked potentials, while overall paradigm complexity had a more graded effect on the P3 peak. These complex auditory paradigms may be useful in understanding speech perception in noise.
NEUROSCIENCE LETTERS
(2022)
Article
Audiology & Speech-Language Pathology
Lisa L. Hunter, Chelsea M. Blankenship, Barbara Shinn-Cunningham, Linda Hood, Lina Motlagh Zadeh, David R. Moore
Summary: Children with listening difficulties (LiD) but normal audiometry are often diagnosed with auditory processing disorder. This study examined electrophysiological evidence for brainstem pathway mechanisms in children with and without LiD, finding that children with LiD performed worse on speech perception and neurophysiological tests, and these differences were related to parent report and speech perception in competing speech ability.
Article
Multidisciplinary Sciences
Haoyu Wang, Bei Li, Yan Lu, Kun Han, Haibin Sheng, Jialei Zhou, Yumeng Qi, Xueling Wang, Zhiwu Huang, Lei Song, Yunfeng Hua
Summary: The study introduced an automatic threshold determination method for ABR testing, which terminates level averaging of ABR recordings when detecting time-locked waveforms through cross-correlation analysis. This method provides a robust and fully automated ABR test with good matching to human readouts.
Article
Neurosciences
Alexis Pinsonnault-Skvarenina, Karina Moin-Darbari, Wulan Zhao, Meibian Zhang, Wei Qiu, Adrian Fuente
Summary: The study aimed to investigate the association between occupational noise exposure and auditory brainstem response (ABR) and speech perception in noise (SPiN) in young factory workers with normal hearing. Results showed no significant association between noise exposure and cochlear synaptopathy measured by ABR and SPiN.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Laura Froehlich, Alexander Mueller, Miriam H. Kropp, Parwis Mir-Salim, Oliver Dziemba, Tobias Oberhoffner, Stefan K. Plontke, Torsten Rahne
Summary: This study analyzed the intensity-latency functions of intraoperative auditory evoked brainstem responses (ABRs) to stimulation by the Vibrant Soundbridge (VSB) active middle ear implant. The results showed that the intensity-latency function slopes of VSB evoked ABRs were similar to acoustic stimulation at high stimulation levels, but with longer latencies. Saturation of latencies occurred for higher stimulation levels due to saturation of audio processor gain. The findings suggest that the analysis of VSB evoked intensity-latency functions allows for the objective assessment of a patient's individual dynamic range.
FRONTIERS IN NEUROLOGY
(2022)
Article
Psychology, Multidisciplinary
Elif Canseza Kaplan, Anita E. Wagner, Paolo Toffanin, Deniz Baskent
Summary: Previous studies have shown that musically trained individuals may have an advantage in speech-on-speech processing. This study aimed to test potential differences between musicians and non-musicians using different measures of spoken language processing. The results revealed that musicians performed better in a sentence recall task and both groups showed reduced gaze fixations to target and competitor words' images as speech maskers increased in complexity during eye-tracking.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Oncology
Isabel Gugel, Florian Grimm, Philip Hartjen, Maria Breun, Julian Zipfel, Marina Liebsch, Hubert Lowenheim, Ulrike Ernemann, Lan Kluwe, Victor-Felix Mautner, Marcos Tatagiba, Martin Ulrich Schuhmann
Summary: Both BAEP and audiometry are essential in the decision-making process for neuro-oncological treatment of NF2-associated VS, with preoperative BAEP and resection amount significantly influencing postoperative hearing outcome. A prediction model indicates that an increase in BAEP class is associated with an increased risk of postoperative hearing deterioration. Larger resection amounts pose a higher risk compared to smaller resections, emphasizing the importance of careful monitoring and adjustment during surgery.