Article
Chemistry, Analytical
Chu Tang, Hongjuan Tong, Bin Liu, Xinan Wang, Yushen Jin, Erli Tian, Fu Wang
Summary: In this study, a novel estrogen receptor alpha (ER α)-targeted near-infrared fluorescence probe was developed for rapid and sensitive detection of hydrazine levels. The probe exhibited good ER α affinity, excellent selectivity, and high biocompatibility. It can visualize hydrazine concentration rapidly and provide high contrast in vivo imaging.
ANALYTICAL CHEMISTRY
(2022)
Review
Biology
Lisanne K. A. Neijenhuis, Lysanne D. A. N. de Myunck, Okker D. Bijlstra, Peter J. K. Kuppen, Denise E. Hilling, Frank J. Borm, Danielle Cohen, J. Sven D. Mieog, Willem H. Steup, Jerry Braun, Jacobus Burggraaf, Alexander L. Vahrmeijer, Merlijn Hutteman
Summary: Lung cancer, particularly non-small cell lung cancer (NSCLC), is prevalent worldwide. Near-infrared (NIR) fluorescence imaging has been tested as an intraoperative technique to localize pulmonary nodules, allowing tumor identification, detection of additional lesions, and prevention of positive resection margins.
Article
Biochemistry & Molecular Biology
Labrinus van Manen, Lizzie D. A. N. de Muynck, Victor M. M. Baart, Shadhvi Bhairosingh, Pieterjan Debie, Alexander L. L. Vahrmeijer, Sophie Hernot, J. Sven D. Mieog
Summary: Molecular fluorescence-guided surgery using near-infrared light has the potential to improve cancer resection rates. This study investigated the feasibility of using a carcinoembryonic antigen-targeting Nanobody conjugated to ZW800-1 for intraoperative imaging of pancreatic ductal adenocarcinoma (PDAC). The results demonstrated specific accumulation of NbCEA5-ZW800-1 in pancreatic tumors, indicating the potential advantages of this imaging technique.
Article
Materials Science, Biomaterials
Junhui Xiao, Siqi Qiu, Qiufeng Ma, Silan Bai, Xinrong Guo, Lishi Wang
Summary: In this study, a near-infrared II fluorescent probe targeting HER-2-positive breast cancer was constructed and compared with a similar structure probe. The results showed that the constructed probe had stronger fluorescence, better targeting ability, and comparatively faster metabolism, highlighting its potential in intraoperative breast cancer navigation.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Engineering, Biomedical
Duo Zhao, Menghong Xu, Shiyuan Yang, Huide Ma, Huiwen Li, Rong Wu, Yu He, Shumin Wang, Xiaolong Liang
Summary: Axillary lymph node metastasis is considered the most important prognostic factor in the treatment of early breast cancer. The current examination methods for accurate diagnosis of early breast cancer with lymph node metastasis are inadequate. Targeted imaging of tumor-associated macrophages (TAM) enables noninvasive and sensitive detection of metastatic lymph nodes, providing valuable guidance for tumor therapy.
Article
Chemistry, Multidisciplinary
Xin Wei, Jingsheng Huang, Chi Zhang, Cheng Xu, Kanyi Pu, Yan Zhang
Summary: Researchers have synthesized a highly bright near-infrared chemiluminophore through molecular engineering of the electron-withdrawing group. This chemiluminophore shows a 3 to 5-fold higher quantum yield compared to existing ones. By combining it with a cathepsin B-responsive moiety, an activatable chemiluminescence probe has been developed for real-time detection of deeply buried tumor tissues and accurate chemiluminescence-guided laparotomy in living mice.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Pharmacology & Pharmacy
Fei Ding, Jing Feng, Xueli Zhang, Jielin Sun, Chunhai Fan, Zhilei Ge
Summary: Optical imaging is crucial in biomedicine and theragnostic, but faces limitations in deep-tissue visualization due to light scattering and tissue autofluorescence. Responsive optical probes are designed for precise diagnosis and surgery excision by specific reactions with biological analytes or disease biomarkers.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Review
Chemistry, Multidisciplinary
Zi'an Wang, Xuan Wang, Jian-Bo Wan, Fujian Xu, Nana Zhao, Meiwan Chen
Summary: This review summarizes the latest progress of NIR-II optical imaging for angiography, including fluorescence imaging, photoacoustic imaging, and optical coherence tomography. It highlights the optimization and application of probes in vascular imaging.
Article
Biotechnology & Applied Microbiology
Giorgia Zambito, Gunja Mishra, Christopher Schliehe, Laura Mezzanotte
Summary: Melanoma is an aggressive type of skin cancer with a poor prognosis. Early detection is crucial for effective therapy. Recent research has shown that the interaction between melanoma cells and the immune system can aid in the development of efficient treatment strategies. This study used engineered macrophages as cell-based sensors to detect metastatic melanoma, demonstrating the potential of using optical imaging technologies to track circulating macrophages for non-invasive detection of the disease.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Review
Chemistry, Multidisciplinary
Hangqi Luo, Shuai Gao
Summary: Phototherapy, including photothermal therapy (PTT) and photodynamic therapy (PDT), is widely used for cancer treatment, but conventional PTT/PDT lack disease recognition ability, resulting in limited therapeutic effects. Integrating fluorescence imaging with PTT/PDT can reveal tumor locations in real-time, enabling early diagnosis and precision treatment. The use of NIR-II fluorescence imaging with PTT/PDT can significantly improve tumor theranostics accuracy and minimize damage to normal tissues.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Oncology
Melissa B. Aldrich, John C. Rasmussen, Sarah M. DeSnyder, Wendy A. Woodward, Wenyaw Chan, Eva M. Sevick-Muraca, Elizabeth A. Mittendorf, Benjamin D. Smith, Michael C. Stauder, Eric A. Strom, George H. Perkins, Karen E. Hoffman, Melissa P. Mitchell, Carlos H. Barcenas, Lynn E. Isales, Simona F. Shaitelman
Summary: This study investigated the use of near-infrared fluorescence lymphatic imaging (NIRF-LI) surveillance to predict early onset of peripheral lymphatic dysfunction as a predictor of breast cancer-related lymphedema (BCRL). The results showed that dermal backflow can predict the development of BCRL months before arm swelling occurs, enabling early treatment to prevent edema and irreversible tissue changes.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Article
Chemistry, Multidisciplinary
Julia Ackermann, Jan Stegemann, Tim Smola, Eline Reger, Sebastian Jung, Anne Schmitz, Svenja Herbertz, Luise Erpenbeck, Karsten Seidl, Sebastian Kruss
Summary: Optical nanosensors based on single-wall carbon nanotubes are able to capture the dynamics of biochemical processes. A one-step phase separation approach has been developed to isolate monochiral (6,4)-SWCNTs from mixed SWCNT samples, enabling high-resolution imaging in the near-infrared spectrum using standard Si-based cameras. (6,4)-SWCNTs modified with (GT)(10)-ssDNA become highly sensitive to the neurotransmitter dopamine, allowing for fast and high-resolution imaging of dopamine release from cells.
Article
Chemistry, Multidisciplinary
Takeshi Fukuda, Shinya Yokomizo, Stefanie Casa, Hailey Monaco, Sophia Manganiello, Haoran Wang, Xiangmin Lv, Amy Daniel Ulumben, Chengeng Yang, Min-Woong Kang, Kazumasa Inoue, Masahiro Fukushi, Toshiyuki Sumi, Cheng Wang, Homan Kang, Kai Bao, Maged Henary, Satoshi Kashiwagi, Hak Soo Choi
Summary: The residual tumor after surgery is the most important prognostic factor for patients with epithelial ovarian cancer. Currently available contrast-enhancing agents have limitations for clinical use due to their low on-target binding, unfavorable pharmacokinetics, and toxicity. The study introduces a novel ultrabright and stable squaraine fluorophore called OCTL14, which demonstrates optimal pharmacokinetics and rapid cellular uptake. The charged squaraine fluorophores also provide durable intraoperative imaging by being retained in lysosomes in a preclinical murine model of ovarian cancer.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Biochemistry & Molecular Biology
Katsunori Teranishi
Summary: Bladder cancer was the twelfth most common cancer worldwide in 2020. This study demonstrates the high effectiveness of the near-infrared fluorescence (NIRF) probe ASP5354 for noninvasive optical imaging of MB49 bladder cancer in mice. ASP5354 was specifically absorbed by cancerous tissue and not by normal tissues in the bladder, allowing for clear differentiation between cancerous and normal tissues using NIRF imaging. This provides new diagnostic possibilities for bladder cancer in humans.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Oncology
Oliver Budner, Tomasz Cwalinski, Jaroslaw Skokowski, Luigi Marano, Luca Resca, Natalia Cwalina, Leszek Kalinowski, Richelle Hoveling, Franco Roviello, Karol Polom
Summary: This study is the first clinical series to propose the use of methylene blue as a fluorescent dye for breast cancer sentinel node biopsy. The study demonstrates the feasibility of using methylene blue as a fluorophore and suggests that dilution can improve fluorescence signal.
Review
Medicine, Research & Experimental
Yu-Jin Lee, Giri Krishnan, Naoki Nishio, Nynke S. van den Berg, Guolan Lu, Brock A. Martin, Stan van Keulen, Alexander D. Colevas, Shrey Kapoor, Jonathan T. C. Liu, Eben L. Rosenthal
Summary: The rate of positive margins in head and neck cancers has remained steady over the past three decades, indicating the need for significant improvements intraoperatively to ensure negative margins. Fluorescence imaging plays a crucial role in guiding surgical oncology for head and neck cancer, offering promising clinical applications and future possibilities.
Article
Radiology, Nuclear Medicine & Medical Imaging
Naoki Nishio, Nynke S. van den Berg, Brock A. Martin, Stan van Keulen, Shayan Fakurnejad, Eben L. Rosenthal, Katheryne E. Wilson
Summary: This study evaluated the potential of using PAMI for photoacoustic imaging to identify LN metastasis in patients with HNSCC. Results showed that PAMI using IRDye800-labeled tumor-specific antibody may help identify occult LN metastasis perioperatively in HNSCC patients.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Letter
Otorhinolaryngology
Marisa E. Hom, Eben L. Rosenthal, Mark Varvares
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2021)
Article
Otorhinolaryngology
Joshua Stramiello, Brian Nuyen, Anirudh Saraswathula, Liza Blumenfeld, Vasu Divi, Eben Rosenthal, Ryan Orosco, Heather M. Starmer
Summary: The study suggests that early feeding in properly selected patients undergoing free flap reconstruction for mucosal defects may not increase the risk of salivary fistula and could potentially improve swallow functional outcomes earlier.
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY
(2021)
Article
Otorhinolaryngology
Melanie D. Hicks, Alyssa K. Ovaitt, Jason C. Fleming, Anna G. Sorace, Patrick N. Song, Ameer Mansur, Yolanda E. Hartman Bs, Eben L. Rosenthal, Jason M. Warram, Carissa M. Thomas
Summary: The study demonstrates that IntegriSense750 shows better predictive performance in flap compromise compared to ICG, with higher signal-to-background ratio. This fluorescence agent may enhance the identification of flap necrosis and potentially improve patient outcomes.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Review
Medicine, Research & Experimental
Kayva L. Crawford, Fernanda V. Pacheco, Yu-Jin Lee, Marisa Hom, Eben L. Rosenthal, Quyen T. Nguyen, Ryan K. Orosco
Summary: Fluorescence-guided surgery (FGS) is a rapidly developing intraoperative technology with many contrast agents under investigation. This review focused on the current state of FGS clinical trials in Otolaryngology, particularly its oncologic applications. A total of 19 studies were included, with 17 focused on FGS for oncologic resection and lymph node detection.
Article
Oncology
Joel W. Neal, Mohana Roy, Kelly Bugos, Christopher Sharp, Peter S. Galatin, Patricia Falconer, Eben L. Rosenthal, Douglas W. Blayney, Shiva Modaressi, Ashley Robinson, Kavitha Ramchandran
Summary: The study aimed to assess the feasibility of implementing a hybrid electronic and paper screening tool for distress in a large integrated cancer center. By using the commonly available patient-reported outcome tool, Patient-Reported Outcomes Measurement Information System-Global Health, a significant number of patient questionnaires were collected, leading to increased referrals to supportive care services for those with distress symptoms.
JCO ONCOLOGY PRACTICE
(2021)
Article
Oncology
Rahul Pal, Marisa E. Hom, Nynke S. van den Berg, Thinzar M. Lwin, Yu-Jin Lee, Andrey Prilutskiy, William Faquin, Eric Yang, Srinivas V. Saladi, Mark A. Varvares, Eben L. Rosenthal, Anand T. N. Kumar
Summary: This study provides the first clinical evidence that fluorescence lifetime (FLT) imaging can provide tumor specificity at the cellular level in patients injected with an EGFR-targeted near infrared fluorescent probe. FLT within EGFR-overexpressing cancer cells is significantly longer than in normal tissue, allowing for high sensitivity and specificity for tumor classification. The mean tissue FLT is spatially correlated with tumor-specific EGFR expression and can be detected through thick biological tissue, suggesting the potential for clinical applications in image guided surgery and cancer diagnostics.
CLINICAL CANCER RESEARCH
(2022)
Article
Nanoscience & Nanotechnology
Giri Krishnan, Aidan Cousins, Nguyen Pham, Valentina Milanova, Melanie Nelson, Shridhar Krishnan, Anil Shetty, Nynke van den Berg, Eben Rosenthal, Suren Krishnan, Peter-John Wormald, Andrew Foreman, Benjamin Thierry
Summary: This study demonstrates the potential of a novel mannose-labeled magnetic iron oxide tracer to overcome the limitations of false negative results in sentinel lymph node biopsy for head and neck cancers. The tracer showed high affinity to the sentinel node and provided a means for intraoperative signal-based node status indication.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Nathan Kauffman, Satyendra Kumar Singh, James Morrison, Kurt R. Zinn
Summary: This study demonstrates the successful inhibition of breast cancer growth (4T1 and EO771) using radiolabeled macroaggregated albumin particles (Bi-212-MAA) as a form of radiation therapy, which showed stable biodistribution in vivo. The potential of this approach can be extended and applied in larger animal models and human clinical trials.
FRONTIERS IN CHEMISTRY
(2023)
Review
Pharmacology & Pharmacy
Nathan Kauffman, James Morrison, Kevin O'Brien, Jinda Fan, Kurt R. Zinn
Summary: A paradigm shift is occurring in cancer diagnosis and therapy with radiopharmaceuticals. This strategy involves using diagnostic imaging to measure tumor uptake of radioactive agent X to select patients for therapy with radioactive agent Y. X-Y pairs, known as radiotheranostics, are being evaluated for intra-arterial dosing to enhance tumor targeting and improve imaging and therapy. Clinical trials are underway to assess these new therapeutic approaches, including the use of alpha-particle therapy with short-lived radioisotopes.
Article
Medicine, Research & Experimental
Kavita Prasad, Rahul Sharma, Daniel Habib, Robert Sinard, Kyle Mannion, Sarah Rohde, Alexander Langerman, James Netterville, Eben Rosenthal, James Lewis, Michael C. Topf
Summary: The study aimed to evaluate the presence of carcinoma in re-resection specimens following initial positive margins during head and neck cancer surgery and its impact on oncologic outcomes. A retrospective chart review was conducted on patients who underwent curative-intent surgery for oral cavity cancer. The results showed that fewer than a third of re-resections contained further malignancy, suggesting difficulty in locating the initial positive margin. Conclusion: The presence of cancer in re-resection specimens and final positive margin status was associated with worse overall survival, but age, T4 disease, and surgery for recurrent oral cavity cancer were independently associated with overall survival.
Proceedings Paper
Engineering, Biomedical
Eric R. Henderson, Paul M. Werth, Xiaochun Xu, Lesley Jarvis, Keith D. Paulsen, P. Jack Hoopes, Eben L. Rosenthal, Brian W. Pogue, Kimberley S. Samkoe
Summary: The study successfully tested a fluorescent dye for sarcomas and found that it maintained its targeting effect even after chemotherapy and radiation, suggesting its potential application in fluorescence-guided surgery.
MOLECULAR-GUIDED SURGERY: MOLECULES, DEVICES, AND APPLICATIONS VIII
(2022)
Article
Chemistry, Analytical
Monica J. Jacobs, Morgan K. Geiger, Suzanne E. Summers, Charles P. DeLuca, Kurt R. Zinn, Dana M. Spence
Summary: The glycation of serum albumin affects the binding of C-peptide and Zn2+ to red blood cells (RBCs), as well as the subsequent release of ATP. This has implications for C-peptide therapy in individuals with type 1 diabetes.
ACS MEASUREMENT SCIENCE AU
(2022)
Article
Biochemical Research Methods
Yueli Liu, Laura E. Hesse, Morgan K. Geiger, Kurt R. Zinn, Timothy J. McMahon, Chengpeng Chen, Dana M. Spence
Summary: A set of 3D-printed analytical devices were developed to investigate the effects of different storage solutions on erythrocytes in transfusion medicine. The results showed that hyperglycemic conditions permanently alter erythrocyte deformability and reduce ATP release. However, normal glycemic storage can mitigate the storage lesion.
Editorial Material
Surgery
Meghal Shah, Tejas S. Sathe, Sukriti Bansal, Anai N. Kothari, Sophie Dream
JOURNAL OF SURGICAL RESEARCH
(2024)
Letter
Surgery
Zafer Turkyilmaz, Ramazan Karabulut, Kaan Sonmez
JOURNAL OF SURGICAL RESEARCH
(2024)
Letter
Surgery
Priyanka Jadhav, Gerald Gollin
JOURNAL OF SURGICAL RESEARCH
(2024)
Review
Surgery
Kheira Hireche, Ludovic Canaud, Pierre Antoine Peyron, Linda Sakhri, Isabelle Serres, Sanaa Kamel, Youcef Lounes, Thomas Gandet, Pierre Alric
Summary: This study evaluated the elastic properties of commonly used vascular substitutes for pulmonary artery replacement and compared their compliance and stiffness indexes to human pulmonary artery. The results showed that allogenic arterial grafts appeared to be the most suitable vascular substitutes in terms of compliance and stiffness for PA replacement.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Margaret Siu, Aixa Perez Coulter, Heather M. Grant, Reginald Alouidor, Michael Tirabassi
Summary: There is no significant difference in adverse respiratory events between intubated, critically ill patients requiring operative intervention who are kept NPO for 6 hours or longer compared to those kept NPO for less than 6 hours. Patients commonly experience periods of fasting much longer than the recommended 6-hour period by the American Society of Anesthesiologists.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Whitney Elks, Allison G. McNickle, Matthew Kelecy, Kavita Batra, Shirley Wong, Shawn Wang, Lisa Angotti, Deborah A. Kuhls, Charles St Hill, Syed F. Saquib, Paul J. Chestovich, Douglas R. Fraser
Summary: This study aimed to compare the effects of early and late enteral feeding after PEG placement on achieving nutritional therapy goals and adverse outcomes. The results showed that patients with early initiation of feeds achieved a higher percentage of goals on day 0 without an increased rate of adverse events.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Manisha B. Bhatia, Cassandra M. Anderson, Abdiwahab N. Hussein, Brian Opondo, Nereah Aruwa, Otieno Okumu, Sarah G. Fisher, Tasha Sparks Joplin, JoAnna L. Hunter-Squires, Brian W. Gray, Peter W. Saula
Summary: This study aimed to understand postoperative pediatric nutrition practices in Kenya and the United States. The results showed that in the United States, patients initiated enteral nutrition earlier and had shorter hospital stays. However, in Kenya, patients initiated enteral nutrition earlier but had no significant difference in hospital stays.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
David P. Stonko, Joseph Edwards, Hossam Abdou, Rebecca Treffalls, Patrick Walker, Jonathan J. Morrison
Summary: Raising mean arterial pressure (MAP) >90 mmHg with norepinephrine can increase gastroduodenal artery (GDA) flow and delay bowel ischemia.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
David R. Mann, Kathryn E. Engelhardt, Barry C. Gibney, Macelyn E. Batten, Eric C. Klipsch, Rupak Mukherjee, Ian C. Bostock
Summary: Pathologic upstaging is associated with decreased overall survival in cT1b esophageal cancer. Esophagectomy has better survival outcomes compared to endoscopic local tumor excision. Neoadjuvant chemoradiation therapy does not improve overall survival in cT1b lesions.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Ross Mudgway, Zachary Tran, Juan C. Quispe Espiritu, Woo Bin Bong, Hayden Schultz, Vamsi Vemireddy, Aarthy Kannappan, Marcos Michelotti, Kaushik Mukherjee, Jeffrey Quigley, Keith Scharf, Daniel Srikureja, Sharon S. Lum, Esther Wu
Summary: Comparison of medium-term outcomes between robotic-assisted cholecystectomy (RC) and laparoscopic cholecystectomy (LC) using validated quality of life (QoL) and pain assessments did not show significant differences.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Ningjie Chen, Haitao Wang, Yang Shao, Jincun Yang, Guodong Song
Summary: This study aimed to compare the therapeutic effects of activated platelet-rich plasma (PRP) prepared from elderly individuals and young adults in treating pressure ulcers (PUs). The results showed that PRP from young adults had higher platelet concentrations and greater production of growth factors, leading to better wound healing.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Brendin R. Beaulieu-Jones, Margaret T. Berrigan, Kortney A. Robinson, Jayson S. Marwaha, Tara S. Kent, Gabriel A. Brat
Summary: Introduction: Prescription opioids, including those prescribed after surgery, have greatly contributed to the US opioid epidemic. Educating opioid prescribers is a crucial component of ensuring the safe use of opioids among surgical patients. This study implemented an annual education curriculum for new surgical prescribers, resulting in significant improvements in knowledge and comfort levels. However, there remains a persistent knowledge and comfort gap among these prescribers.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Sneha G. Bhat, Madhuri Nagaraj, Courtney Balentine, Timothy Hogan, Jennie Meier, Hillary Prince, Kareem Abdelfattah, Herbert Zeh, Benjamin Levi
Summary: This pilot study examined the effects of a structured mental fitness program on academic surgeons and found significant improvement in Positive Intelligence (PQ) scores, as well as increased connectedness and shared language among participants. However, there were no significant changes in sleep, well-being, or teaching evaluations.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Kristin E. Cox, Michael A. Turner, Siamak Amirfakhri, Thinzar M. Lavin, Mojgan Hosseini, Pradipta Ghosh, Marygorret Obonyo, Takashi Murakami, Robert M. Hoffman, Paul J. Yazaki, Michael Bouvet
Summary: This study demonstrates the potential of using humanized anti-carcinoembryonic antigen (CEA) antibodies conjugated with near-infrared dyes to specifically label gastric cancers in mouse models. Orthotopic models showed bright and specific labeling with more than ten times higher tumor-to-background ratios compared to the control. This tumor-specific fluorescent antibody has promising potential as a clinical tool for improving visualization of gastric cancer margins during surgical resection.
JOURNAL OF SURGICAL RESEARCH
(2024)
Review
Surgery
Sarah Maki, Melissa Leon, Emily Glenn, Tiffany Tanner, Crystal Krause
Summary: This scoping review analyzed the literature on the use of broadband personality tests in the bariatric surgical population to optimize weight loss outcomes. The study found significant associations between personality scales and weight loss, but inconsistent reporting of outcome measures made it challenging to draw concrete conclusions. The American Society for Metabolic and Bariatric Surgery recommends standardization of outcome reporting to improve the reliability of predicting weight loss outcomes.
JOURNAL OF SURGICAL RESEARCH
(2024)