4.5 Article

Voice, swallowing and quality of life in patients after transoral laser surgery for supraglottic carcinoma

Journal

JOURNAL OF SURGICAL ONCOLOGY
Volume 98, Issue 3, Pages 184-189

Publisher

WILEY
DOI: 10.1002/jso.21101

Keywords

supraglottic carcinoma; laser surgery; voice; swallowing; quality of life

Funding

  1. Korea Government (MOEHRD, Basic Research Promotion Fund) [KRF-2007-331-E00146]
  2. Ministry of Health AMP
  3. AMP
  4. Welfare, the National R&D Program for Cancer Control [0620160]

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Background: Transoral laser surgery is a conservative surgical method used to treat supraglottic carcinomas, but little is known about functional and quality of life (QOL) outcomes relative to extent of resection. Methods: We prospectively examined functional and oncological outcomes of 21 patients with T1-T3 supraglottic carcinomas underwent partial (group A, n = 8) or radical (group B, n = 13) laser supraglottic resection and bilateral neck dissection. Subjective and objective evaluation of voice, swallowing and QOL before and after endoscopic supraglottic resection were compared between the two groups. Results: No major complications were encountered, but local recurrence developed in two patients (9%). Vocal function was not generally affected by surgery. Postsurgical swallowing and social eating scores were higher in group B than in group A (P < 0.05). Aspiration occurred in most patients soon after surgery, but recovered within 3-6 months, with recovery being faster in group A. Three-year locoregional control, disease-free survival and overall survival rates were 81%, 71% and 79%, respectively. Conclusion: Swallowing was affected by the extent of laser resection for supraglottic carcinomas, but eventually recovered in most patients, indicating favourable functional and oncological outcomes.

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