Journal
PLANTA MEDICA
Volume 81, Issue 12-13, Pages 995-1002Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0035-1546182
Keywords
Diphasiastrum; Lycopodiaceae; classification; lycopodium alkaloids
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Funding
- Icelandic Research Fund
- University of Iceland Research Fund
- Eimskip Fund of the University of Iceland
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The genus Diphasiastrum includes at least 23 species distributed primarily across the northern temperate and subarctic areas of the world. These plants produce an array of lycopodium alkaloids, and some species such as Diphasiastrum complanatum have been used in traditional medicine for ages for various conditions. Hybridization is common in this group of plants and they have always been a challenge for taxonomists and other scientists studying them. To date, 11 Diphasiastrum species have been reported to produce lycopodium alkaloids. In this review, reported alkaloids and their distribution patterns across these species along with taxonomical and bioactivity considerations are reviewed and discussed.
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