Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase

Title
Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase
Authors
Keywords
-
Journal
JOURNAL OF STRUCTURAL BIOLOGY
Volume 176, Issue 1, Pages 52-59
Publisher
Elsevier BV
Online
2011-06-24
DOI
10.1016/j.jsb.2011.06.001

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