Article
Endocrinology & Metabolism
Estifanos N. Habtemichael, Don T. Li, Joao Paulo Camporez, Xavier O. Westergaard, Chloe Sales, Xinran Liu, Francesc Lopez-Giraldez, Stephen G. DeVries, Hanbing Li, Diana M. Ruiz, Kenny Y. Wang, Bhavesh S. Sayal, Sofia Gonzalez Zapata, Pamela Dann, Stacey N. Brown, Sandro Hirabara, Daniel F. Vatner, Leigh Goedeke, William Philbrick, Gerald Shulman, Jonathan S. Bogan
Summary: Insulin-stimulated TUG cleavage pathway regulates gene expression to promote lipid oxidation and thermogenesis, linking glucose uptake to organismal energy expenditure. Attenuation of this mechanism may promote obesity as it contributes to the thermic effect of food.
Article
Sport Sciences
Tomas I. Gonzales, Kate Westgate, Stefanie Hollidge, Tim Lindsay, Katrien Wijndaele, Nita G. Forouhi, Simon Griffin, Nick Wareham, Soren Brage
Summary: This study examined the relationship between cardiorespiratory fitness and population subgroups and seasonal trends in a population-based cohort of UK adults. The findings showed that older generations are comparatively fitter than younger generations, but the decline in fitness with age is less steep than anticipated. Physical activity energy expenditure and BMI were found to be stronger determinants of cardiorespiratory fitness than other characteristics, emphasizing the importance of modifiable physical activity behaviors in public health interventions.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Construction & Building Technology
Vivek Anand, Devi Sendhil, E. Rajasekar
Summary: This paper investigates the effects of different activity intensities on metabolic rate and physiological responses through controlled climate chamber experiments. The study finds significant differences in metabolic rate among different age and BMI groups, as well as impacts of temperature, humidity, and other environmental factors on metabolic rate.
BUILDING AND ENVIRONMENT
(2022)
Article
Sport Sciences
David P. Looney, Elizabeth M. Lavoie, Sai V. Vangala, Lucas D. Holden, Peter S. Figueiredo, Karl E. Friedl, Peter N. Frykman, Jason W. Hancock, Scott J. Montain, J. Luke Pryor, William R. Santee, Adam W. Potter
Summary: The study aimed to develop and validate an equation for estimating metabolic rates during heavy load carriage for the US Army Load Carriage Decision Aid (LCDA), an integrated software mission planning tool.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Engineering, Biomedical
Jing Xie, Min Bao, Xinyu Hu, Werner J. H. Koopman, Wilhelm T. S. Huck
Summary: Cells respond to mechanical cues from the extracellular matrix by adjusting their cytoskeleton and forming focal adhesions, which can lead to changes in ATP levels and activation of AMPK. This can affect cell spreading and tension, as well as influence stem cell fate in response to ECM mechanics. Lowered ATP levels on softer substrates limit cellular mechanoresponses.
Article
Orthopedics
Irfan A. Khan, Amer Haffar, Justin A. Magnuson, Christian Ong, Matthew S. Austin, Chad A. Krueger, Jess H. Lonner
Summary: The study found that surgeons experience significantly higher physiological strain and stress while performing THA compared to TKA, showing higher heart rate, energy expenditure, and minute ventilation during THA. Surgeons should take into consideration the higher physical demand associated with THAs and ensure adequate personal preparation and sequence of cases when scheduling THAs and TKAs.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Medicine, General & Internal
Yan Wang, Huijuan Li, Juan Wang, Wei Zhao, Zhipeng Zeng, Li Hao, Yifang Yuan, Yuwei Lin, Yangfeng Wu, Zhengzhen Wang
Summary: This study aimed to establish normal reference values of peak oxygen uptake (VO2peak) for cardiorespiratory fitness (CRF) in Chinese adults using cardiorespiratory exercise testing (CPET). The results showed significant differences in VO2peak between men and women, with a decrease in VO2peak as age increased.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Nutrition & Dietetics
Javier T. Gonzalez, Alan M. Batterham, Greg Atkinson, Dylan Thompson
Summary: The idea of increasing physical activity directly adding to total energy expenditure (TEE) in humans is challenged by the energy constrained hypothesis. Evidence supporting this hypothesis is limited due to various methodological issues, and future studies should address these limitations by using randomized controlled trials. The available evidence suggests that increasing physical activity mostly has an additive effect on TEE, although some energy remains unaccounted for, and the degree of energy balance may further moderate this effect.
ADVANCES IN NUTRITION
(2023)
Article
Biology
Yanis Zekri, Romain Guyot, Ines Garteizgogeascoa Suner, Laurence Canaple, Amandine Gautier Stein, Justine Vily Petit, Denise Aubert, Sabine Richard, Frederic Flamant, Karine Gauthier
Summary: This study used transcriptome and cistrome analyses to identify direct target genes of thyroid hormone (T3) in brown adipocytes and developed a new mouse model to study the role of T3 in brown adipose tissue (BAT). The results showed that T3 plays a crucial role in regulating lipid and glucose metabolism and BAT proliferation, providing new insights into the pathways by which T3 activates energy expenditure through adaptive thermogenesis in BAT.
Editorial Material
Biochemistry & Molecular Biology
Raghav Jain, Judith Simcox
Summary: Localized hyperthermia has been found to activate thermogenic mechanisms, leading to increased energy expenditure and reduced body weight in both mice and humans.
Article
Rehabilitation
Kazuaki Oyake, Yasuto Baba, Yuki Suda, Jun Murayama, Ayumi Mochida, Kunitsugu Kondo, Yohei Otaka, Komito Momose
Summary: The study found that in patients with stroke, the increase in cardiac output was slower than the increase in arterial-venous oxygen difference, affecting oxygen uptake kinetics. The ratio of cardiac output to oxygen uptake time constants was associated with motor function and gait speed.
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Vivian Doerr, Ryan N. Montalvo, Branden L. Nguyen, Franccesco P. Boeno, Michael D. Sunshine, Victoria E. Bindi, David D. Fuller, Ashley J. Smuder
Summary: DOX chemotherapy can lead to cardiorespiratory dysfunction, while HBO therapy may increase muscle antioxidant expression. However, HBO therapy is not sufficient to prevent DOX-induced cardiorespiratory dysfunction.
Article
Clinical Neurology
Maxence Compagnat, Jean-yves Salle, Maria Vinti, Romain Joste, Jean Christophe Daviet
Summary: This study evaluated the validity of different oxygen cost estimation equations for calculating total energy expenditure (TEE) using ActigraphGT3x in individuals with stroke sequelae. Results showed that the Polese and Compagnat equations had the best validity parameters, suggesting that using oxygen cost prediction equations is a promising approach for improving TEE assessment by accelerometers in post-stroke individuals.
NEUROREHABILITATION AND NEURAL REPAIR
(2022)
Article
Nutrition & Dietetics
Cecilia Veraar, Arabella Fischer, Martin H. Bernardi, Isabella Sulz, Mohamed Mouhieddine, Martin Dworschak, Edda Tschernko, Andrea Lassnigg, Michael Hiesmayr
Summary: Longitudinal changes in resting energy expenditure, oxygen delivery, and distribution and processing may occur after major surgery. This study analyzed the pattern of these parameters in critically ill patients who died during hospitalization. The results showed that survivors experienced a transition from negative to positive energy balance, while non-survivors had decreased oxygen delivery and extraction. A lower resting energy expenditure was associated with worse survival at various time points. Non-survivors seemed to be unable to adapt metabolically from the early phase to the later phase.
Article
Medicine, General & Internal
Shuhao Lin, Sofia Cienfuegos, Mark Ezpeleta, Kelsey Gabel, Vasiliki Pavlou, Andrea Mulas, Kaitie Chakos, Mara McStay, Jackie Wu, Lisa Tussing-Humphreys, Shaina J. Alexandria, Julienne Sanchez, Terry Unterman, Krista A. Varady
Summary: This study compared time-restricted eating (TRE) with calorie restriction (CR) and control group to evaluate their effects on weight control and cardiometabolic risk reduction. The results showed that both TRE and CR were similarly effective in weight loss compared to the control group. However, in a racially diverse population, TRE was not more effective than CR.
ANNALS OF INTERNAL MEDICINE
(2023)