Article
Sport Sciences
Samuel D'Emanuele, Cantor Tarperi, Alberto Rainoldi, Federico Schena, Gennaro Boccia
Summary: This study investigated the neural and contractile determinants of the rate of force development (RFD) in burst-like isometric knee extensions. The results showed that muscle excitation was the main determinant of early RFD, while contractile characteristics were more relevant for late RFD.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Physiology
Everett C. Minchew, Nicholas C. Williamson, Andrew T. Readyoff, Joseph M. McClung, Espen E. Spangenburg
Summary: Assessing contractile function of skeletal muscle in murine models is commonly employed in laboratory research. This study aimed to characterize the functional properties of hindlimb muscles in different mouse strains. The data reveals both unique differences and similarities between the muscles in different genetic backgrounds. Additionally, the strain of the mouse could potentially influence the measured biological outcome and interact with any genetic manipulation or therapeutic intervention. Therefore, careful consideration of the genetic background and documentation of the strain of mouse is critical in experimental design and publication.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Neurosciences
Benjamin I. Binder-Markey, Lomas S. Persad, Alexander Y. Shin, William J. Litchy, Kenton R. Kaufman, Richard L. Lieber
Summary: By transplanting the gracilis muscle from the thigh to the arm and directly measuring its properties and function, this study validated the relationship between isometric contractile properties and whole muscle properties in the human body.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Physiology
James L. Nuzzo, David S. Kennedy, Harrison T. Finn, Janet L. Taylor
Summary: The contemporary procedure for assessing voluntary activation of the knee extensor muscles with TMS is invalid, but a modified procedure may improve validity in select individuals meeting rigorous eligibility criteria.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Sport Sciences
Jacobo A. Rubio-Arias, Domingo Jesus Ramos-Campo, Pedro E. Alcaraz, Jose Fernando Jimenez Diaz, Anthony J. Blazevich
Summary: The study showed that 6 weeks of whole-body vibration training can increase isometric plantar flexor strength at multiple joint angles in young healthy adults, without detectable changes in EMG, muscle architecture, or body composition.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Physiology
Ian C. Smith, Franziska Onasch, Katarzyna Krysciak, Jan Celichowski, Walter Herzog
Summary: Boost and sag in human muscle are diminished in repeated contractions with short rest periods, but re-established or enhanced with long rest periods. This sensitivity to contractile history may have applications in strength and power sports.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Atsuki Fukutani, Shiho Kunimatsu, Tadao Isaka
Summary: This study examined the influence of caffeine on cross-bridge dynamics and found that the effect of caffeine on cross-bridge dynamics is negligible. The ergogenic effect of caffeine is primarily achieved through facilitating Ca2+ release.
SCIENTIFIC REPORTS
(2022)
Article
Sport Sciences
Rebekah S. Carpenter, Michael A. Samaan, Jody L. Clasey, Tim A. Butterfield, Fan Gao, Peter A. Hardy, Lance M. Bollinger
Summary: This study investigated the relationship between diffusion tensor imaging (DTI) parameters of the vastus lateralis (VL) and in vivo knee extensor contractile function. The results showed that mean diffusivity (MD) and radial diffusivity (RD) were moderately correlated with peak twitch force and rate of force development, while fractional anisotropy (FA) and axial diffusivity (AD) were moderately inversely related to percent change in maximal voluntary isometric contraction (MVIC) following exercise.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Neurosciences
Alessandro Del Vecchio, Carina Marconi Germer, Thomas M. Kinfe, Stefano Nuccio, Francois Hug, Bjoern Eskofier, Dario Farina, Roger M. Enoka
Summary: The purpose of this study was to identify the low-dimensional latent components, called motor unit modes, underlying the discharge rates of motor units in knee extensors and hand muscles during submaximal isometric contractions. Factor analysis identified two independent motor unit modes that captured most of the covariance of the motor unit discharge rates. The distribution of motor unit modes was different between hand and knee muscles, with a continuous distribution found for the knee muscles.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Biology
Tommaso Minuti, Paolo Cigni, Michele Costagli, Alessandro Cucini, Erika Cione, Samuele Melotto, Stefano Rapetti, Leonardo Ricotti, Roberto Cannataro
Summary: The study evaluated isometric muscle strength using an exoskeleton in a standing position, finding high reliability and favorable joint positions for testing. This new method could serve as a valid alternative for assessing strength, particularly in the field of football.
Article
Physiology
Qun Yang, Xin Jia He, Ying Duan Li, Yong Zhi Zhang, Cong Shi Ding, Guo Xing Li, Jian Sun
Summary: This study conducted a meta-analysis on the efficacy and dose-response relationship of blood flow restriction training on muscle strength. The findings showed that blood flow restriction training significantly improved lower limb muscle strength, and various factors such as training load, mode, frequency, duration, and maximum cuff pressure influenced the muscle function.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Biology
Axel J. Fenwick, David C. Lin, Bertrand C. W. Tanner
Summary: Muscle contraction results from force-generating interactions between myosin and actin, with factors influencing cross-bridge kinetics at the molecular level propagating through tissues to modulate whole-muscle function. Researchers found that cross-bridge kinetics vary with whole-muscle length during intact, isometric contraction, suggesting a feedback pathway between muscle function and cross-bridge activity. The study highlights the complexity of muscle contraction and the potential impact of length-dependent cross-bridge kinetics on force generation and energetics.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2021)
Article
Orthopedics
Johanneke Hartog, Sandra Dijkstra, Joke Fleer, Pim van der Harst, Massimo A. Mariani, Lucas H. van der Woude
Summary: The study evaluated the reliability, responsiveness, and level of discomfort of the newly developed Q-Force II device for measuring isometric knee extensor strength in healthy middle-aged and elderly adults. Results showed excellent test-retest reliability, low discomfort, and suitability for clinical settings.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Biochemistry & Molecular Biology
Yuji Kanazawa, Ryo Miyachi, Takashi Higuchi, Hiaki Sato
Summary: Aging increases the expression and immunoreactivity of collagen I, III, and VI in both slow- and fast-twitch muscles, as well as collagen IV in slow-twitch muscles. However, collagen IV expression and immunoreactivity in fast-twitch muscles are unaffected by aging. The expression of the collagen synthesis marker decreases while the expression of collagen degradation markers increases with aging, indicating a shift towards collagen degradation with age.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Ryan G. Savoury, Armin Kibele, Kevin Power, Nehara Herat, Shahab Alizadeh, David Behm
Summary: The study aimed to investigate the effects of 10-min of anodal transcranial direct current stimulation (a-tDCS) on quadriceps isometric maximal voluntary contraction (MVC) force and fatigue endurance. The results showed that a-tDCS led to a significant reduction in absolute MVC force in the ipsilateral leg, while s-tDCS caused a significant reduction in the contralateral leg. Furthermore, a-tDCS resulted in significantly lower relative MVC force in the ipsilateral quadriceps compared to s-tDCS. The findings suggest that a-tDCS may not effectively enhance maximal force or endurance and could potentially impair quadriceps force production.
Article
Medicine, Research & Experimental
Camille O. Muller, Makii Muthalib, Denis Mottet, Stephane Perrey, Gerard Dray, Marion Delorme, Claire Duflos, Jerome Froger, Binbin Xu, Germain Faity, Simon Pla, Pierre Jean, Isabelle Laffont, Karima K. A. Bakhti
Summary: This study aims to evaluate the impact of adding anodal high-definition tDCS to an intensive 3-week upper limb VRT and conventional therapy program in chronic stroke patients. The project recruits 58 chronic stroke patients for a standard 3-week rehabilitation program, with outcome measures including primary wolf motor function test and secondary measures of upper limb function, impairment, compensation, and activities of daily living.
Article
Neurosciences
Meyi Duleme, Stephane Perrey, Gerard Dray
Summary: This study examines the frequency band modulations underlying working memory load and the role of executive control using scalp EEG data. The results show that decoding accuracy is higher for combined frequency bands compared to isolated frequency bands, and that there are transient changes in frequency band clusters during specific time windows.
COGNITIVE NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Frank Imbach, Stephane Perrey, Romain Chailan, Thibaut Meline, Robin Candau
Summary: This study aims to provide a transferable methodology in the context of sport performance modelling, with a special focus on the generalization of models. Data from seven elite short track speed skaters were collected over a three-month training period. Different models were compared, including the variable dose-response model, elastic net, principal component regression, and random forest models. The results showed that the ENET model achieved greater generalization and predictive accuracy performances.
SCIENTIFIC REPORTS
(2022)
Correction
Biochemical Research Methods
Yashika Arora, Pushpinder Walia, Mitsuhiro Hayashibe, Makii Muthalib, Shubhajit Roy Chowdhury, Stephane Perrey, Anirban Dutta
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Biochemical Research Methods
Yashika Arora, Pushpinder Walia, Mitsuhiro Hayashibe, Makii Muthalib, Shubhajit Roy Chowdhury, Stephane Perrey, Anirban Dutta
Summary: This study utilized systems biology approaches to investigate the initial transient hemodynamic response to tDCS. The findings suggest that the perturbation of potassium concentration in the perivascular space during tDCS had the least mean square error and the lowest Akaike information criterion in the model fitting.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Psychology, Biological
I Hoang, L. Paire-Ficout, R. Derollepot, S. Perrey, H. Devos, M. Ranchet
Summary: Executive functions are crucial for successful walking tasks, especially when performing dual tasks. Previous studies have focused on the prefrontal cortex activity in older adults under different walking conditions, but little is known about the changes in dorsolateral prefrontal cortex (DLPFC) activity during the early stages of aging. This study aimed to compare the changes in DLPFC activity during simple and dual task walking across three age groups. The results revealed that older adults exhibited increased DLPFC activity in the right hemisphere during simple task walking, but they seemed to have enough cognitive resources to maintain performance during dual task walking. These findings suggest the presence of compensation mechanisms in early aging, which may have implications for fall risk assessment.
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
Quentin Chenot, Caroline Hamery, Evelyne Lepron, Pierre Besson, Xavier De Boissezon, Stephane Perrey, Sebastien Scannella
Summary: This study investigated the effects of tRNS on performance in a complex task and found that high-definition tRNS was more effective than simple-definition tRNS in enhancing long-term performance, with faster learning rate and better performance retention.
SCIENTIFIC REPORTS
(2022)
Article
Sport Sciences
Frank Imbach, Nicolas Sutton-Charani, Jacky Montmain, Robin Candau, Stephane Perrey
Summary: The emergence of Fitness-Fatigue impulse response models (FFMs) has allowed for the investigation of training effects on athletic performance. However, their effectiveness in describing and predicting performance is limited due to simplified physiological processes and a univariate consideration of factors. Therefore, machine-learning methods can enhance performance prediction by incorporating physiological representations and multivariate algorithms.
SPORTS MEDICINE-OPEN
(2022)
Review
Sport Sciences
Stephane Perrey
Summary: This article emphasizes the importance of cognitive demand in training monitoring and proposes methods for better applying cognitive demand indicators in various sports settings. While the assessment of cognitive demand is still in its early stages, it may yield fruitful results if rigorous protocols and deep understanding of neurobehavioral and cognitive aspects are employed.
Article
Multidisciplinary Sciences
Frank Imbach, Waleed Ragheb, Valentin Leveau, Romain Chailan, Robin Candau, Stephane Perrey
Summary: This study aims to predict individual A-V profiles using GNSS measurements in real-world situations. The study found that GNSS features have limited relevance for predicting individual A-V profiles, but new signal processing features have potential in modeling athletic performance or injury occurrence.
SCIENTIFIC REPORTS
(2022)
Article
Physiology
Alexandre P. Gutknecht, Martin Gonzalez-Figueres, Thomas Brioche, Olivier Maurelli, Stephane Perrey, Francois B. Favier
Summary: The purpose of this study was to determine the optimal altitude for hypoxic training and investigate the relationship between pulse oxygen saturation and training-induced performance improvement. The results showed that hypoxic training at an altitude of 1,500 meters significantly improved anaerobic performance, while the correlation between pulse oxygen saturation and performance improvement during training was weak.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Neurosciences
Stephane Perrey
Summary: While physical abilities are known to be important for elite sport performance, recent focus has shifted towards the role of cognitive processes. Noninvasive transcranial electrical stimulation (tES) has been found to modulate brain functioning and improve cognitive functions related to sports performance. However, more research is needed to fully understand its effectiveness and benefits, particularly in elite athletes. Modulating inhibitory control through tES over the frontal cortex may significantly enhance mental performance. Further studies are required to assess the long-term effects of tES as an ergogenic aid in conjunction with other cognitive training methods.
Article
Neurosciences
Ludovic Molle, Alexandre Coste, Charles-Etienne Benoit, Gerard Derosiere, Stefan Janaqi, Stephane Perrey, Arnaud Dupeyron
Summary: The emergence of consciousness is a biological mystery, and little is known about the physiological mechanisms underlying subjective experience. Recent research suggests that the breathing phase can modulate attention, with inhalation improving perceptual awareness and decision-making speed. This study tested this hypothesis and found that inhalation enhances perceptual awareness and speeds up objective decision-making.
JOURNAL OF NEUROPHYSIOLOGY
(2023)
Article
Sport Sciences
Lenaic Borot, Benjamin Pageaux, Davy Laroche, Gregoire Vergotte, Romuald Lepers, Stephane Perrey
Summary: Compared to concentric exercise, eccentric exercise has a higher mental demand and activates the frontoparietal network, especially when the exercise intensity is fixed by torque.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Clinical Neurology
Zaineb Ajra, Binbin Xu, Gerard Dray, Jacky Montmain, Stephane Perrey
Summary: The study proposes the use of shallow neural networks to analyze EEG signals in order to diagnose dementia at an early stage. The results show that the CNN-based models outperformed conventional methods and achieved an accuracy of 94.54% in the test dataset.
FRONTIERS IN NEUROLOGY
(2023)