Article
Plant Sciences
Qing Wang, Yali Sun, Fang Wang, Pei-Cheng Huang, Yinying Wang, Xinsen Ruan, Liang Ma, Xin Li, Michael Kolomiets, Xiquan Gao
Summary: The disruption of a 9-LOX gene, ZmLOX5, leads to increased susceptibility to Gibberella stalk rot (GSR) in maize, indicating its role in defense. Transcriptome and oxylipin profiling revealed that JA biosynthetic pathway genes were up-regulated while multiple 9-LOX pathway genes were down-regulated in the infected zmlox5-3 mutant, suggesting an antagonistic interaction between 9-oxylipins and JAs in maize resistance to F. graminearum.
FRONTIERS IN PLANT SCIENCE
(2021)
Review
Plant Sciences
Delia A. Narvaez-Barragan, Omar E. Tovar-Herrera, Arturo Guevara-Garcia, Mario Serrano, Claudia Martinez-Anaya
Summary: Cell wall integrity is crucial for plant defense against biotic and abiotic stresses. Expansins, which modify cell walls, can enhance or weaken plant resistance to pathogens. Changes in cell wall mechanical properties can directly influence the outcome of pathogen infection, while expansins also play a role in triggering defense responses.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Indira Saado, Khong-Sam Chia, Ruben Betz, Andre Alcantara, Aladar Pettko-Szandtner, Fernando Navarrete, John C. D'Auria, Michael Kolomiets, Michael Melzer, Ivo Feussner, Armin Djamei
Summary: The study shows that the smut fungus Ustilago maydis secretes effector proteins to suppress host defense responses in maize plants, with Rip1 playing a key role in inhibiting host immunity and affecting antioxidant reactions. By relocalizing the host factor ZmLox3, the fungus can partially suppress ROS burst responses in maize plants.
Article
Plant Sciences
Meng-Meng Chen, Si-Ru Yang, Jian Wang, Ya-Li Fang, You-Liang Peng, Jun Fan
Summary: Oxysterol-binding protein-related proteins (ORPs) play important roles in plant-pathogen interactions, triggering oxidative bursts and promoting plant innate immunity; they are also essential for the growth, development, and virulence of fungal pathogens.
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Article
Biochemistry & Molecular Biology
Peiguo Yuan, Eli Borrego, Yong -Soon Park, Zachary Gorman, Pei-Cheng Huang, Jordan Tolley, Shawn A. Christensen, Jantana Blanford, Aruna Kilaru, Robert Meeley, Hisashi Koiwa, Stefan Vidal, Alisa Huffaker, Eric Schmelz, Michael Kolomiets
Summary: Researchers discovered that a tonoplast-localized enzyme, ZmLOX5, and its product, 9,10-KODA, in corn have insect resistance properties and enhance the production of defense metabolites. Additionally, ZmLOX5 contributes to insect defense by modulating the signaling of another enzyme, ZmLOX10. This study revealed a novel anti-herbivory mechanism and hormone-like signaling activity.
Article
Biology
Alexandra Menna, Susanne Dora, Gloria Sancho-Andres, Anurag Kashyap, Mukesh Kumar Meena, Kamil Sklodowski, Debora Gasperini, Nuria S. Coll, Clara Sanchez-Rodriguez
Summary: The study reveals dynamic transcriptional changes in both fungus and root during interaction, with downregulation of primary CW synthesis genes being one of the early plant responses. Enhanced resistance to Fusarium oxysporum was observed in Arabidopsis mutants impaired in primary CW cellulose synthesis, while lignin-deficient mutants showed susceptibility similar to wildtype plants.
Article
Fisheries
Fei Zhao, Xueqing Zhu, Yuting Deng, Dongqi Li, Yingtiao Lai, Hua Gong, Feifei Wang, Zhibin Huang, Aiping Tan
Summary: The cytokine interleukin-34 (IL-34) and its receptors, CSF-1R1 and CSF-1R2, play essential roles in immune surveillance, inflammation, and cell proliferation in snakehead fish. The expression of IL-34 and CSF-1R is regulated by bacterial pathogens and various cytokines, and their activation promotes leukocyte proliferation and activates NF-kappa B and AP-1 signaling pathways.
AQUACULTURE REPORTS
(2023)
Article
Plant Sciences
Alfonso Gonzalo De la Rubia, Maria Luz Centeno, Victor Moreno-Gonzalez, Maria De Castro, Penelope Garcia-Angulo
Summary: Infection of common bean with Pseudomonas syringae pv. phaseolicola led to increased expression of PvWAK1 at early stages, but the antioxidant response was not efficient, resulting in cellular damage. This recognition of the pathogen only resulted in modest and slow activation of host defenses, leading to high susceptibility to P. syringae pv. phaseolicola.
Article
Microbiology
Sean Turner, Brent Raisley, Kimberly Roach, Sandra Bajana, Melissa E. Munroe, Judith A. James, K. Mark Coggeshall, Susan Kovats
Summary: Gram-positive bacterial infections can cause organ failure and death in sepsis. Bacillus anthracis PGN, a component shed during bacterial replication, can promote sepsis-like pathology. This study found that purified Bacillus anthracis PGN can activate human dendritic cells (DCs), promote the production of proinflammatory cytokines, and induce the differentiation of T(H)17 cells.
Article
Biochemistry & Molecular Biology
Isabel Monte, Sakiko Ishida, Angel M. Zamarreno, Mats Hamberg, Jose M. Franco-Zorrilla, Gloria Garcia-Casado, Caroline Gouhier-Darimont, Philippe Reymond, Kosaku Takahashi, Jose M. Garcia-Mina, Ryuichi Nishihama, Takayuki Kohchi, Roberto Solano
NATURE CHEMICAL BIOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Andrea Chini, Isabel Monte, Angel M. Zamarreno, Mats Hamberg, Steve Lassueur, Philippe Reymond, Sally Weiss, Annick Stintzi, Andreas Schaller, Andrea Porzel, Jose M. Garcia-Mina, Roberto Solano
NATURE CHEMICAL BIOLOGY
(2018)
Article
Plant Sciences
Yovanny Izquierdo, Satish Kulasekaran, Pablo Benito, Bran Lopez, Ruth Marcos, Tomas Cascon, Mats Hamberg, Carmen Castresana
PLANT CELL AND ENVIRONMENT
(2018)
Article
Biochemistry & Molecular Biology
Johan Kolmert, Sergio Pineiro-Hermida, Mats Hamberg, Joshua A. Gregory, Iciar P. Lopez, Alexander Fauland, Craig E. Wheelock, Sven-Erik Dahlen, Jose G. Pichel, Mikael Adner
PROSTAGLANDINS & OTHER LIPID MEDIATORS
(2018)
Article
Biochemistry & Molecular Biology
David Fuchs, Mats Hamberg, C. Magnus Skold, Asa M. Wheelock, Craig E. Wheelock
JOURNAL OF LIPID RESEARCH
(2018)
Article
Plant Sciences
Jorge Vicente, Guillermina M. Mendiondo, Jarne Pauwels, Victoria Pastor, Yovanny Izquierdo, Christin Naumann, Mahsa Movahedi, Daniel Rooney, Daniel J. Gibbs, Katherine Smart, Andreas Bachmair, Julie E. Gray, Nico Dissmeyer, Carmen Castresana, Rumiana V. Ray, Kris Gevaert, Michael J. Holdsworth
Article
Biochemistry & Molecular Biology
Ernst H. Oliw, Mats Hamberg
Article
Biochemical Research Methods
Ernst H. Oliw, Mats Hamberg
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2020)
Article
Biochemistry & Molecular Biology
David Fuchs, Xiao Tang, Anna-Karin Johnsson, Sven-Erik Dahlen, Mats Hamberg, Craig E. Wheelock
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
(2020)
Article
Plant Sciences
Ruben Fernandez-Santos, Yovanny Izquierdo, Ana Lopez, Luis Muniz, Marta Martinez, Tomas Cascon, Mats Hamberg, Carmen Castresana
PLANT AND CELL PHYSIOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Anna-Karin Johnsson, Elin Ronnberg, David Fuchs, Johan Kolmert, Jesper Safholm, Hans-Erik Claesson, Mats Hamberg, Craig E. Wheelock, Gunnar Nilsson, Sven-Erik Dahlen
Summary: This study found that in human mast cells, 15-HETE is produced by COX-1, with the 15(S) isomer selectively depleted by further metabolism. This indicates that 15-HETE cannot be used as an indicator of 15-LOX activity in cellular studies.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
(2021)
Article
Allergy
Anna-Karin Johnsson, Jeong-Hee Choi, Elin Ronnberg, David Fuchs, Johan Kolmert, Mats Hamberg, Barbro Dahlen, Craig E. Wheelock, Sven-Erik Dahlen, Gunnar Nilsson
Summary: Inhibition of hPGDS effectively blocks mast cell-dependent PGD(2) formation, leading to redirected use of the intermediate PGH(2) and shunting into biosynthesis of TXA(2). However, the levels of TXA(2) did not reach those of PGD(2) in naive cells. It remains to be determined if this diversion occurs in vivo and has clinical relevance.
CLINICAL AND EXPERIMENTAL ALLERGY
(2021)
Article
Multidisciplinary Sciences
Tamara Vellosillo, Jose R. Dinneny, Chris R. Somerville, David W. Ehrhardt
Summary: The study identified an unknown gene, TRANVIA (TVA), which is transcriptionally coregulated with CESA genes required for primary cell wall synthesis. TVA mutant exhibits enhanced sensitivity to cellulose synthesis inhibitors, reduced cellulose content, and defects in dynamics, density, and secretion of CSCs to the plasma membrane compared to wild type.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biology
Yovanny Izquierdo, Ruben Fernandez-Santos, Tomas Cascon, Carmen Castresana