Review
Physics, Multidisciplinary
Ping Xie
Summary: The review focuses on the mechanisms of how Kinesin converts chemical energy from ATP hydrolysis into mechanical energy for movement, presenting qualitative and quantitative comparisons between proposed models and experimental studies including structural, biochemical and single-molecule approaches.
COMMUNICATIONS IN THEORETICAL PHYSICS
(2021)
Article
Biochemistry & Molecular Biology
Irene Pertici, Lorenzo Bongini, Marco Caremani, Massimo Reconditi, Marco Linari, Gabriella Piazzesi, Vincenzo Lombardi, Pasquale Bianco
Summary: The study analyzes the mechanical performances of vertebrate skeletal muscle during isometric and isotonic contractions, and their corresponding energy consumption, to define the coupling between mechanical and biochemical steps in the myosin-actin energy transduction cycle. The emergent properties of a simplified synthetic nanomachine, consisting of eight HMM molecules and an actin filament, are also assessed. The study predicts the relationships between energetic and mechanical properties of fast skeletal muscle, both in vivo and in vitro, through a three-state model of myosin-actin interaction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Mihaela-Carmen Unciuleac, Aviv Meir, Chaoyou Xue, Garrett M. Warren, Eric C. Greene, Stewart Shuman
Summary: Mycobacterial AdnAB is a pivotal enzyme involved in DNA repair, particularly in the recombination process of double-strand breaks (DSBs). The study highlights the crucial role of AdnB Trp325 as the key active component of the enzyme, showing that its interaction with the DNA tracking strand is essential for ATP hydrolysis and DNA translocation, without which the enzyme's activity during DSB resection is significantly impaired.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Chemistry, Physical
Akihiro Kameda, Sunao Shimomoto, Hiroyuki Tajima, Jun-ichi Yamada, Tokuji Yokomatsu, Kazusuke Maenaka, Takeshi Komino
Summary: By investigating the mode coupling distance of whispering gallery modes (WGMs) and using a specific fabrication process, it was concluded that long-range mode coupling in organic thin films can occur between microdisks.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Physics, Fluids & Plasmas
Chenji Li, Brato Chakrabarti, Pedro Castilla, Achal Mahajan, David Saintillan
Summary: This study presents an integrated chemomechanical model of freely swimming spermatozoa that produces spontaneous oscillations with realistic beating patterns and trajectories. The swimming velocity is found to exhibit two maxima associated with distinct swimming modes, and the model also provides an estimate of swimming efficiency, which peaks at low sperm number.
PHYSICAL REVIEW FLUIDS
(2023)
Article
Engineering, Geological
Xiaoyue Li, Xinjiang Zheng, Yongfu Xu, Chaoyang Li
Summary: This paper explores the time-dependent free swelling behavior of bentonite in saline solution and its influencing factors. By developing a constitutive model that incorporates the fractal swelling theory into the existing chemomechanical coupling consolidation model, the 1D free swelling behavior of bentonite in saline solution is successfully estimated. The results show that the permeability coefficient, volume change coefficient, and ion diffusion coefficient have certain effects on the swelling behavior.
INTERNATIONAL JOURNAL OF GEOMECHANICS
(2022)
Article
Energy & Fuels
Jia Liang, Baofeng Yao, Yonghong Xu, Hongguang Zhang, Fubin Yang, Anren Yang, Yan Wang, Yuting Wu
Summary: This study builds and tests a pneumatic motor on a test bench under different inlet pressures, operation modes, and three driving cycles. The results show that with an increase in rotation speed, the output power and efficiency first increase and then decrease, and the compression air consumption rate decreases. With an increase in torque, the rotation speed decreases, and the power output and efficiency first increase and then decrease. With an increase in mass flow rate, the torque increases, and the power output and efficiency first increase and then decrease. The pneumatic motor achieves the best performance under a rotation speed of 800-1200 rpm, where power output, efficiency, and compressed air consumption rates are 1498 W, 13.6%, and 10 J/g, respectively. The pneumatic motor achieves the best power output and efficiency under the UDDS driving cycle.
Article
Chemistry, Physical
Lionel Foulon, Anne Hemeryck, Georges Landa, Marie Brut
Summary: This article presents a method that combines the Static Mode approach with Quantum Mechanics calculations to guide the exploration of energy landscape and reduce computational time and human effort. The coupling of QMSM allows for screening and selection of relevant directions to study diffusion in atomic systems.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Energy & Fuels
Alexey Loskutov, Andrey Kurkin, Andrey Shalukho, Ivan Lipuzhin, Rustam Bedretdinov
Summary: This article focuses on the integration of proton-exchange membrane fuel cells (PEMFCs) into power supply systems and proposes a hybrid energy complex (HEC) based on PEMFCs and lithium iron phosphate batteries. The performance of a 1 kW PEMFC under steady and dynamic modes is analyzed, obtaining relationships between variables such as hydrogen consumption, hydrogen volume for generating 1 kWh, and PEMFC efficiency at different load currents. It is recommended to switch to battery operation within a specific range of load changes where the PEMFC efficiency significantly decreases.
Article
Energy & Fuels
Dong Yan, Yonghong Xu, Hongguang Zhang, Fubin Yang, Liang Tong, Yifan Yang, Yan Wang, Yuting Wu
Summary: This study investigates the effects of parallel operation mode on the power performance of pneumatic motors (PMs) and finds that the parallel operation mode can improve the power performance, economy, and energy conversion efficiency of compressed air vehicles (CAVs).
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
(2022)
Article
Green & Sustainable Science & Technology
Yonghong Xu, Hongguang Zhang, Fubin Yang, Liang Tong, Dong Yan, Yifan Yang, Yan Wang, Yuting Wu
Summary: This study proposes a parallel operation mode of a pneumatic motor to improve the power performance, energy conversion efficiency, and economy of the compressed air energy storage system. Experimental results show that the performance of the system can be enhanced when the pneumatic motor works in parallel mode.
Article
Automation & Control Systems
Marco Castangia, Nicola Barletta, Christian Camarda, Stefano Quer, Enrico Macii, Edoardo Patti
Summary: In smart grids, consumers can participate in demand response programs to reduce household power consumption during peak hours. However, utility companies face challenges in implementing these programs due to their negative impact on user comfort. This article uses neural networks and clustering algorithms to analyze power signatures of appliances and identify different operational modes. By studying washing machines and dishwashers, the analysis reveals distinct working programs based on energy consumption and duration, providing insights for improving demand response programs and reducing overall energy usage by promoting lighter operation modes.
IEEE TRANSACTIONS ON INDUSTRIAL INFORMATICS
(2023)
Article
Energy & Fuels
Pawel Orkisz, Bogdan Sapinski
Summary: This study presents the features of a 2-DOF vibration reduction system (VRS) equipped with a linear electrodynamic motor in passive, semi-active, and active mode. The VRS model was formulated and simulation tests were conducted to analyze its dynamic performance and energy consumption. Experimental tests were also carried out to evaluate the effectiveness of the VRS in each mode and compare the results with simulation data. A sliding mode algorithm was used for motor control in the active mode, while the equivalent damping coefficient analysis was employed in the semi-active mode.
Article
Chemistry, Physical
Weize Yuan, Harikrishnan Vijayamohanan, Shao-Xiong Lennon Luo, Keith Husted, Jeremiah A. Johnson, Timothy M. Swager
Summary: In this study, oil-in-water colloidal particles of conducting polymer were fabricated via in situ interfacial polymerization. These particles exhibited a unique core-shell structure and could change their shapes and configurations by altering the charge state of the polymer at the interface. The expansion mechanism of the particles relied on the repulsion caused by the positively charged polymer and the insertion of reduced negatively charged oxidant species. The particles could expand up to 400% of their initial dimensions and retain their structure, and could also shrink back to their original size.
CHEMISTRY OF MATERIALS
(2022)
Article
Physics, Multidisciplinary
David Halg, Thomas Gisler, Eric C. Langman, Shobhna Misra, Oded Zilberberg, Albert Schliesser, Christian L. Degen, Alexander Eichler
Summary: We demonstrate the parametric coupling between two modes of a silicon nitride membrane by applying an oscillating voltage to a sharp metal tip near the membrane surface. The modes exchange energy periodically and faster than their free energy decay rate when the voltage oscillation frequency matches the mode frequency difference. This flexible method can be useful for rapid state control and transfer between modes, and is an important step towards parametric spin sensing experiments with membrane resonators.
PHYSICAL REVIEW LETTERS
(2022)
Article
Cell Biology
Jan Steinkuehler, Bartosz Rozycki, Cory Alvey, Reinhard Lipowsky, Thomas R. Weikl, Rumiana Dimova, Dennis E. Discher
JOURNAL OF CELL SCIENCE
(2019)
Article
Chemistry, Multidisciplinary
Mehmet Can Ucar, Reinhard Lipowsky
Article
Multidisciplinary Sciences
Jan Steinkuehler, Roland L. Knorr, Ziliang Zhao, Tripta Bhatia, Solveig M. Bartelt, Seraphine Wegner, Rumiana Dimova, Reinhard Lipowsky
NATURE COMMUNICATIONS
(2020)
Article
Chemistry, Physical
Pallavi Banerjee, Reinhard Lipowsky, Mark Santer
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
(2020)
Article
Chemistry, Multidisciplinary
Debjit Roy, Jan Steinkuehler, Ziliang Zhao, Reinhard Lipowsky, Rumiana Dimova
Correction
Multidisciplinary Sciences
Jan-Hendrik Trosemeier, Sophia Rudorf, Holger Loessner, Benjamin Hofner, Andreas Reuter, Thomas Schulenborg, Ina Koch, Isabelle Bekeredjian-Ding, Reinhard Lipowsky, Christel Kamp
SCIENTIFIC REPORTS
(2020)
Article
Nanoscience & Nanotechnology
Ohad Vonshak, Yiftach Divon, Stefanie Foerste, David Garenne, Vincent Noireaux, Reinhard Lipowsky, Sophia Rudorf, Shirley S. Daube, Roy H. Bar-Ziv
NATURE NANOTECHNOLOGY
(2020)
Article
Chemistry, Multidisciplinary
Rikhia Ghosh, Vahid Satarifard, Andrea Grafmueller, Reinhard Lipowsky
Summary: In this study, budding and fission processes of lipid nanovesicles with a size below 50 nm were reported using coarse-grained molecular dynamics simulations. The processes are influenced by solute concentration and solvent conditions, with budding being reversible and unexpected morphological transformations observed under poor solvent conditions. This reveals a nanoscale mechanism for the budding and fission of nanovesicles, arising from the interplay between membrane elasticity and solute-mediated membrane adhesion.
Article
Multidisciplinary Sciences
Lado Otrin, Agata Witkowska, Nika Marusic, Ziliang Zhao, Rafael B. Lira, Fotis L. Kyrilis, Farzad Hamdi, Ivan Ivanov, Reinhard Lipowsky, Panagiotis L. Kastritis, Rumiana Dimova, Kai Sundmacher, Reinhard Jahn, Tanja Vidakovic-Koch
Summary: Replacing lipids with polymers can partially address the durability issue in artificial cells, and the study on SNARE-mediated fusion in synthetic amphiphile membranes has identified bending rigidity and pore edge tension as key parameters for fusion.
NATURE COMMUNICATIONS
(2021)
Review
Biochemistry & Molecular Biology
Reinhard Lipowsky, Rikhia Ghosh, Vahid Satarifard, Aparna Sreekumari, Miftakh Zamaletdinov, Bartosz Rozycki, Markus Miettinen, Andrea Grafmueller
Summary: Biological and biomimetic membranes based on lipid bilayers play a crucial role in drug delivery. Recent molecular dynamics simulations have provided insights into the spatio-temporal remodeling of individual bilayers and nanovesicles. The concept of leaflet tensions, which control stability, lipid flip-flops, shape transformations, and adhesion/fusion of nanovesicles, has been highlighted in these studies.
Review
Biochemistry & Molecular Biology
Reinhard Lipowsky
Summary: Condensate droplets form in solutions where macromolecules undergo phase separation. This phenomenon has been observed both in biochemical analysis and in living cells. The review focuses on the interactions between condensate droplets and biomimetic and biological membranes.
Article
Chemistry, Physical
Simon Christ, Thomas Litschel, Petra Schwille, Reinhard Lipowsky
Summary: The study investigates shape oscillations of giant unilamellar vesicles (GUVs) caused by the Min protein system, where MinD and MinE proteins periodically attach to and detach from the membrane, driven by ATP hydrolysis. The oscillations can be understood in terms of spontaneous curvature changing periodically, with the vesicle shape transforming from symmetric to asymmetric and back during each cycle. The radius of the narrow membrane neck connecting the subcompartments undergoes periodic oscillations with an average time period of 56 seconds.
Article
Chemistry, Physical
Ana Elisa Bergues-Pupo, Reinhard Lipowsky, Ana Vila Verde
Article
Chemistry, Physical
Tripta Bhatia, Simon Christ, Jan Steinkuehler, Rumiana Dimova, Reinhard Lipowsky
Article
Materials Science, Biomaterials
Ivan Ivanov, Rafael B. Lira, T-Y Dora Tang, Titus Franzmann, Adam Klosin, Lucas Caire da Silva, Anthony Hyman, Katharina Landfester, Reinhard Lipowsky, Kai Sundmacher, Rumiana Dimova
ADVANCED BIOSYSTEMS
(2019)