EstablishingChlamydomonas reinhardtiias an industrial biotechnology host

A techno-economic analysis of industrial production of marine microalgae as a source of EPA and DHA-rich raw material for aquafeed: Research challenges and possibilities

(2015) Matilde S. Chauton et al.   AQUACULTURE

Microalgal lipids biochemistry and biotechnological perspectives

(2014) Stamatia Bellou et al.   BIOTECHNOLOGY ADVANCES

Triacylglyceride Production and Autophagous Responses in Chlamydomonas reinhardtii Depend on Resource Allocation and Carbon Source

(2014) Matthew P. Davey et al.   EUKARYOTIC CELL

The Path to Triacylglyceride Obesity in the sta6 Strain of Chlamydomonas reinhardtii

(2014) Ursula Goodenough et al.   EUKARYOTIC CELL

Successful Transient Expression of Cas9 and Single Guide RNA Genes in Chlamydomonas reinhardtii

(2014) Wenzhi Jiang et al.   EUKARYOTIC CELL

Improvement of hydrogen yield of lba -transgenic Chlamydomonas reinhardtii caused by increasing respiration and impairing photosynthesis

(2014) Lili Xu et al.   INTERNATIONAL JOURNAL OF HYDROGEN ENERGY

Rapid and tunable post-translational coupling of genetic circuits

(2014) Arthur Prindle et al.   NATURE

iGEM 2.0—refoundations for engineering biology

(2014) Cristina Vilanova et al.   NATURE BIOTECHNOLOGY

Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals

(2014) Evan J Olson et al.   NATURE METHODS

A brief history of synthetic biology

(2014) D. Ewen Cameron et al.   NATURE REVIEWS MICROBIOLOGY

Synthetic biology tools for programming gene expression without nutritional perturbations in Saccharomyces cerevisiae

(2014) R. Scott McIsaac et al.   NUCLEIC ACIDS RESEARCH

Enhancement of extraplastidic oil synthesis inChlamydomonas reinhardtiiusing a type-2 diacylglycerol acyltransferase with a phosphorus starvation-inducible promoter

(2014) Masako Iwai et al.   PLANT BIOTECHNOLOGY JOURNAL

High-Throughput Genotyping of Green Algal Mutants Reveals Random Distribution of Mutagenic Insertion Sites and Endonucleolytic Cleavage of Transforming DNA

(2014) R. Zhang et al.   PLANT CELL

Cytosine deaminase as a negative selectable marker for the microalgal chloroplast: a strategy for the isolation of nuclear mutations that affect chloroplast gene expression

(2014) Rosanna E. B. Young et al.   PLANT JOURNAL

Plastidial Expression of Type II NAD(P)H Dehydrogenase Increases the Reducing State of Plastoquinones and Hydrogen Photoproduction Rate by the Indirect Pathway in Chlamydomonas reinhardtii

(2014) A. Baltz et al.   PLANT PHYSIOLOGY

Unraveling Vitamin B12-Responsive Gene Regulation in Algae

(2014) K. E. Helliwell et al.   PLANT PHYSIOLOGY

Using Natural Selection to Explore the Adaptive Potential of Chlamydomonas reinhardtii

(2014) Marie-Mathilde Perrineau et al.   PLoS One

Total Synthesis of a Functional Designer Eukaryotic Chromosome

(2014) N. Annaluru et al.   SCIENCE

Edible oils from microalgae: insights in TAG accumulation

(2014) A.J. Klok et al.   TRENDS IN BIOTECHNOLOGY

Green genes: bioinformatics and systems-biology innovations drive algal biotechnology

(2014) Maarten J.M.F. Reijnders et al.   TRENDS IN BIOTECHNOLOGY

The Chlamydomonas genome project: a decade on

(2014) Ian K. Blaby et al.   TRENDS IN PLANT SCIENCE

Bioinformatics Analysis of Alternative Polyadenylation in Green Alga Chlamydomonas reinhardtii Using Transcriptome Sequences from Three Different Sequencing Platforms

(2014) Zhixin Zhao et al.   G3-Genes Genomes Genetics

Accurate, Model-Based Tuning of Synthetic Gene Expression Using Introns in S. cerevisiae

(2014) Ido Yofe et al.   PLoS Genetics

TALE activation of endogenous genes in Chlamydomonas reinhardtii

(2014) Han Gao et al.   Algal Research-Biomass Biofuels and Bioproducts

The roots—a short history of industrial microbiology and biotechnology

(2013) Klaus Buchholz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A matter of detail: Assessing the true potential of microalgal biofuels

(2013) Daniel Klein-Marcuschamer et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protein design in systems metabolic engineering for industrial strain development

(2013) Zhen Chen et al.   Biotechnology Journal

Potential of industrial biotechnology with cyanobacteria and eukaryotic microalgae

(2013) René H Wijffels et al.   CURRENT OPINION IN BIOTECHNOLOGY

Central Carbon Metabolism and Electron Transport in Chlamydomonas reinhardtii: Metabolic Constraints for Carbon Partitioning between Oil and Starch

(2013) Xenie Johnson et al.   EUKARYOTIC CELL

Comparative genomics in Chlamydomonas and Plasmodium identifies an ancient nuclear envelope protein family essential for sexual reproduction in protists, fungi, plants, and vertebrates

(2013) J. Ning et al.   GENES & DEVELOPMENT

Transcriptome analysis of Chlamydomonas reinhardtii during the process of lipid accumulation

(2013) Hexin Lv et al.   GENOMICS

Metabolic engineering of Phaeodactylum tricornutum for the enhanced accumulation of omega-3 long chain polyunsaturated fatty acids

(2013) Mary L. Hamilton et al.   METABOLIC ENGINEERING

Engineering dynamic pathway regulation using stress-response promoters

(2013) Robert H Dahl et al.   NATURE BIOTECHNOLOGY

Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay

(2013) Michael E. Lee et al.   NUCLEIC ACIDS RESEARCH

Repression of Essential Chloroplast Genes Reveals New Signaling Pathways and Regulatory Feedback Loops inChlamydomonas

(2013) Silvia Ramundo et al.   PLANT CELL

Synthetic biology in plastids

(2013) Lars B. Scharff et al.   PLANT JOURNAL

Expanding the spectral palette of fluorescent proteins for the green microalgaChlamydomonas reinhardtii

(2013) Beth A. Rasala et al.   PLANT JOURNAL

Analysis ofChlamydomonasthiamin metabolism in vivo reveals riboswitch plasticity

(2013) Michael Moulin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Analysis of Tandem Repeats in Plants and Green Algae

(2013) Zhixin Zhao et al.   G3-Genes Genomes Genetics

Synthetic biology of cyanobacteria: unique challenges and opportunities

(2013) Bertram M. Berla et al.   Frontiers in Microbiology

Metabolic shifts: a fitness perspective for microbial cell factories

(2012) Anisha Goel et al.   BIOTECHNOLOGY LETTERS

Flux balance analysis of primary metabolism in Chlamydomonas reinhardtii

(2012) Nanette R Boyle et al.   BMC Systems Biology

Functional analysis of three type-2 DGAT homologue genes for triacylglycerol production in the green microalga Chlamydomonas reinhardtii

(2012) M. La Russa et al.   JOURNAL OF BIOTECHNOLOGY

The future of metabolic engineering and synthetic biology: Towards a systematic practice

(2012) Vikramaditya G. Yadav et al.   METABOLIC ENGINEERING

Synthetic biology and the development of tools for metabolic engineering

(2012) Jay D. Keasling   METABOLIC ENGINEERING

Transcriptome-Wide Changes in Chlamydomonas reinhardtii Gene Expression Regulated by Carbon Dioxide and the CO2-Concentrating Mechanism Regulator CIA5/CCM1

(2012) W. Fang et al.   PLANT CELL

Nuclear gene targeting inChlamydomonasusing engineered zinc-finger nucleases

(2012) Irina Sizova et al.   PLANT JOURNAL

Robust Expression and Secretion of Xylanase1 in Chlamydomonas reinhardtii by Fusion to a Selection Gene and Processing with the FMDV 2A Peptide

(2012) Beth A. Rasala et al.   PLoS One

Renewable energy from Cyanobacteria: energy production optimization by metabolic pathway engineering

(2011) Naira Quintana et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A model-based method for investigating bioenergetic processes in autotrophically growing eukaryotic microalgae: Application to the green algae Chlamydomonas reinhardtii

(2011) Guillaume Cogne et al.   BIOTECHNOLOGY PROGRESS

TAG, You’re it! Chlamydomonas as a reference organism for understanding algal triacylglycerol accumulation

(2011) Sabeeha S Merchant et al.   CURRENT OPINION IN BIOTECHNOLOGY

Do Red and Green Make Brown?: Perspectives on Plastid Acquisitions within Chromalveolates

(2011) Richard G. Dorrell et al.   EUKARYOTIC CELL

Metabolic modeling of Chlamydomonas reinhardtii: energy requirements for photoautotrophic growth and maintenance

(2011) Anna M. J. Kliphuis et al.   JOURNAL OF APPLIED PHYCOLOGY

Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases

(2011) Suzanne M. Ma et al.   METABOLIC ENGINEERING

Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism

(2011) R. L. Chang et al.   Molecular Systems Biology

Phytozome: a comparative platform for green plant genomics

(2011) David M. Goodstein et al.   NUCLEIC ACIDS RESEARCH

The chloroplast transformation toolbox: selectable markers and marker removal

(2011) Anil Day et al.   PLANT BIOTECHNOLOGY JOURNAL

Improved heterologous protein expression in the chloroplast of Chlamydomonas reinhardtii through promoter and 5′ untranslated region optimization

(2011) Beth A. Rasala et al.   PLANT BIOTECHNOLOGY JOURNAL

Proteomic profiling of oil bodies isolated from the unicellular green microalga Chlamydomonas reinhardtii: With focus on proteins involved in lipid metabolism

(2011) Hoa M. Nguyen et al.   PROTEOMICS

Essence of life: essential genes of minimal genomes

(2011) Mario Juhas et al.   TRENDS IN CELL BIOLOGY

Metabolic engineering of Escherichia coli for biotechnological production of high-value organic acids and alcohols

(2010) Chao Yu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Synthetic biology approaches in drug discovery and pharmaceutical biotechnology

(2010) Heinz Neumann et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Improved biohydrogen production with an expression of codon-optimized hemH and lba genes in the chloroplast of Chlamydomonas reinhardtii

(2010) Shuangxiu Wu et al.   BIORESOURCE TECHNOLOGY

Genome-wide analysis of alternative splicing in Chlamydomonas reinhardtii

(2010) Adam Labadorf et al.   BMC GENOMICS

An inducible artificial microRNA system for Chlamydomonas reinhardtii confirms a key role for heat shock factor 1 in regulating thermotolerance

(2010) Stefan Schmollinger et al.   CURRENT GENETICS

Biodiesel from algae: challenges and prospects

(2010) Stuart A Scott et al.   CURRENT OPINION IN BIOTECHNOLOGY

Synthetic biology: applications come of age

(2010) Ahmad S. Khalil et al.   NATURE REVIEWS GENETICS

Enhanced chloroplast transgene expression in a nuclear mutant of Chlamydomonas

(2010) Laure Michelet et al.   PLANT BIOTECHNOLOGY JOURNAL

Production of therapeutic proteins in algae, analysis of expression of seven human proteins in the chloroplast of Chlamydomonas reinhardtii

(2010) Beth A. Rasala et al.   PLANT BIOTECHNOLOGY JOURNAL

ChlamyCyc: an integrative systems biology database and web-portal for Chlamydomonas reinhardtii

(2009) Patrick May et al.   BMC GENOMICS

Algal Lipid Bodies: Stress Induction, Purification, and Biochemical Characterization in Wild-Type and StarchlessChlamydomonas reinhardtii

(2009) Zi Teng Wang et al.   EUKARYOTIC CELL

TheARG9Gene Encodes the Plastid-ResidentN-Acetyl Ornithine Aminotransferase in the Green AlgaChlamydomonas reinhardtii

(2009) Claire Remacle et al.   EUKARYOTIC CELL

The Metabolome ofChlamydomonas reinhardtiifollowing Induction of Anaerobic H2Production by Sulfur Depletion

(2009) Timmins Matthew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stable Plastid Transformation in Nicotiana benthamiana

(2009) Seyed Javad Davarpanah et al.   JOURNAL OF PLANT BIOLOGY

An integrative approach towards completing genome-scale metabolic networks

(2009) Nils Christian et al.   Molecular BioSystems

Metabolic network analysis integrated with transcript verification for sequenced genomes

(2009) Ani Manichaikul et al.   NATURE METHODS

Strategies to facilitate transgene expression in Chlamydomonas reinhardtii

(2009) Alke Eichler-Stahlberg et al.   PLANTA

Green Transcription Factors: A Chlamydomonas Overview

(2008) D. M. Riano-Pachon et al.   GENETICS

Diversification of the Core RNA Interference Machinery in Chlamydomonas reinhardtii and the Role of DCL1 in Transposon Silencing

(2008) J. A. Casas-Mollano et al.   GENETICS

Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene

(2008) Jennifer R. Anthony et al.   METABOLIC ENGINEERING

Gaussia-luciferase as a sensitive reporter gene for monitoring promoter activity in the nucleus of the green alga Chlamydomonas reinhardtii

(2008) Ovidiu Ruecker et al.   MOLECULAR GENETICS AND GENOMICS

Gene silencing by artificial microRNAs in Chlamydomonas

(2008) Tao Zhao et al.   PLANT JOURNAL

Generation ofChlamydomonasstrains that efficiently express nuclear transgenes

(2008) Juliane Neupert et al.   PLANT JOURNAL

Highly specific gene silencing by artificial microRNAs in the unicellular alga Chlamydomonas reinhardtii

(2008) Attila Molnar et al.   PLANT JOURNAL

High-confidence prediction of global interactomes based on genome-wide coevolutionary networks

(2008) D. Juan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA