Large-scale production of pharmaceutical proteins in plant cell culture-the protalix experience

The CRISPR/Cas9 system for plant genome editing and beyond

(2015) Luisa Bortesi et al.   BIOTECHNOLOGY ADVANCES

Characterization of a chemically modified plant cell culture expressed human α-Galactosidase-A enzyme for treatment of Fabry disease

(2015) Tali Kizhner et al.   MOLECULAR GENETICS AND METABOLISM

Plant-based oral delivery of β-glucocerebrosidase as an enzyme replacement therapy for Gaucher's disease

(2015) Yoseph Shaaltiel et al.   PLANT BIOTECHNOLOGY JOURNAL

Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor

(2014) Nicole Raven et al.   BIOTECHNOLOGY AND BIOENGINEERING

Etanercept: A Review of Its Use in Autoimmune Inflammatory Diseases

(2014) Lesley J. Scott   DRUGS

Taliglucerase alfa: An enzyme replacement therapy using plant cell expression technology

(2014) Gregory A. Grabowski et al.   MOLECULAR GENETICS AND METABOLISM

Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines

(2014) Brian J. Ward et al.   VACCINE

Glycosylation and functionality of recombinant β-glucocerebrosidase from various production systems

(2013) Yoram Tekoah et al.   BIOSCIENCE REPORTS

Commercial Aspects of Pharmaceutical Protein Production in Plants

(2013) Rainer Fischer et al.   CURRENT PHARMACEUTICAL DESIGN

First plant-made biologic approved

(2012) Jeffrey L Fox   NATURE BIOTECHNOLOGY

Transcription Activator-Like Effector Nucleases Enable Efficient Plant Genome Engineering

(2012) Y. Zhang et al.   PLANT PHYSIOLOGY

Preclinical and Clinical Development of Plant-Made Virus-Like Particle Vaccine against Avian H5N1 Influenza

(2010) Nathalie Landry et al.   PLoS One

Zinc fingers on target

(2009) Matthew H. Porteus   NATURE

High-frequency modification of plant genes using engineered zinc-finger nucleases

(2009) Jeffrey A. Townsend et al.   NATURE

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

(2009) Vipula K. Shukla et al.   NATURE

Remorin, a Solanaceae Protein Resident in Membrane Rafts and Plasmodesmata, Impairs Potato virus X Movement

(2009) S. Raffaele et al.   PLANT CELL

Expression of a transgene exchanged by the recombinase-mediated cassette exchange (RMCE) method in plants

(2009) Kazuya Nanto et al.   PLANT CELL REPORTS

Homologous recombination-mediated knock-in targeting of theMET1agene for a maintenance DNA methyltransferase reproducibly reveals dosage-dependent spatiotemporal gene expression in rice

(2009) Takaki Yamauchi et al.   PLANT JOURNAL

Targeted transgene integration in plant cells using designed zinc finger nucleases

(2009) Charles Q. Cai et al.   PLANT MOLECULAR BIOLOGY

Site-Specific Integration of Transgenes in Soybean via Recombinase-Mediated DNA Cassette Exchange

(2009) Z. Li et al.   PLANT PHYSIOLOGY

Down-regulated expression of plant-specific glycoepitopes in alfalfa

(2008) Christophe Sourrouille et al.   PLANT BIOTECHNOLOGY JOURNAL

Considerations for extraction of monoclonal antibodies targeted to different subcellular compartments in transgenic tobacco plants

(2008) Sally Hassan et al.   PLANT BIOTECHNOLOGY JOURNAL

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

(2008) Richard Strasser et al.   PLANT BIOTECHNOLOGY JOURNAL

A toolbox and procedural notes for characterizing novel zinc finger nucleases for genome editing in plant cells

(2008) Andriy Tovkach et al.   PLANT JOURNAL

RNA Silencing in Plants: Yesterday, Today, and Tomorrow

(2008) A. Eamens et al.   PLANT PHYSIOLOGY

Co-expression of proteinase inhibitor enhances recombinant human granulocyte–macrophage colony stimulating factor production in transgenic rice cell suspension culture

(2008) Tae-Geum Kim et al.   PROTEIN EXPRESSION AND PURIFICATION

Recombinant therapeutic proteins: Production platforms and challenges

(2007) Theo Dingermann   Biotechnology Journal