Review
Oncology
Anao Zhang, Bradley Zebrack, Chiu Yi Tan, Emily Walling, Rashmi Chugh
Summary: This study conducted a systematic review and meta-analysis of psychosocial, behavioral, and supportive interventions for pediatric, adolescent, and young adult cancer survivors, showing an overall moderate and statistically significant treatment effect size. However, interventions were not effective for certain outcome domains, and less effective among adolescent and young adult compared to pediatric cancer survivors.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2021)
Article
Psychology, Multidisciplinary
Jessica R. Gorman, Karen S. Lyons, Jennifer Barsky Reese, Chiara Acquati, Ellie Smith, Julia H. Drizin, John M. Salsman, Lisa M. Flexner, Brandon Hayes-Lattin, S. Marie Harvey
Summary: This study aims to develop a feasible and acceptable couple-based intervention to reduce reproductive and sexual health distress among young adult breast and gynecologic cancer survivor couples. Through systematic adaptation and integration of stakeholder perspectives, the resulting virtual intervention, Opening the Conversation, will be evaluated in a randomized controlled trial.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Oncology
Sylvia L. Crowder, Acadia W. Buro, Marilyn Stern
Summary: This study summarized the effectiveness of physical activity interventions on physical functioning, body composition, and quality of life in pediatric, adolescent, and young adult cancer survivors. Results showed mixed improvements in physical activity behaviors, with future research needed to explore interventions specifically for young adult cancer survivors. Personalized physical activity components and behavior change techniques should be emphasized to maximize physical health and quality of life improvements.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Elizabeth J. Siembida, Bryce B. Reeve, Brad J. Zebrack, Mallory A. Snyder, John M. Salsman
Summary: The study examined the variability in HRQOL among adolescent and young adult cancer survivors, finding that treatment status and developmental stage significantly impacted symptoms and functioning, with developmental stage being a more critical predictor than cancer type.
Article
Nutrition & Dietetics
Acadia W. Buro, Marilyn Stern, Tiffany L. Carson
Summary: This study examined the associations between mental health, eating beliefs, and health behaviors in young adult cancer survivors. The results showed that perceived stress, anxiety, and depression were associated with increased added sugar intake and eating beliefs, while perceived stress and depression were associated with reduced vegetable intake. This highlights the importance of addressing mental health issues in health behavior interventions for this population.
Review
Oncology
Brooke Cherven, Amani Sampson, Sharon L. Bober, Kristin Bingen, Natasha Frederick, David R. Freyer, Gwendolyn P. Quinn
Summary: This study summarizes the literature on sexual function among adolescent and young adult cancer survivors, finding that they experience a burden of sexual dysfunction and interventions are needed to support sexual health and psychosexual adjustment. Collaboration between organizations is necessary to advance assessment of sexual dysfunction and test interventions to improve sexual health among this population.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)
Article
Psychology, Multidisciplinary
Michael A. Hoyt, Ashley Wei-Ting Wang, Raymond Carrillo Ceja, Jennifer S. Cheavens, Michael A. Daneshvar, Darren R. Feldman, Samuel A. Funt, Christian J. Nelson
Summary: This study developed a intervention called Goal-focused Emotion-regulation Therapy (GET) to improve distress symptoms, emotion regulation, and goal navigation skills in young adult testicular cancer survivors. The results showed that GET is a feasible and acceptable intervention for reducing adverse outcomes after testicular cancer for young adults.
ANNALS OF BEHAVIORAL MEDICINE
(2023)
Article
Urology & Nephrology
Vicky Lehmann, Cynthia A. Gerhardt, Katja Baust, Peter Kaatsch, Mariet Hagedoorn, Marrit A. Tuinman
Summary: This study assessed the psychosexual development and sexual satisfaction of young adult survivors of childhood cancer. The results showed that most survivors had normative psychosexual development, except for sexual debut. Overall, survivors reported favorable sexual satisfaction and functioning.
JOURNAL OF SEXUAL MEDICINE
(2022)
Article
Oncology
L. M. E. van Erp, H. Maurice-Stam, L. C. M. Kremer, W. J. E. Tissing, H. J. H. van der Pal, L. Beek, A. C. H. de Vries, M. M. van den Heuvel-Eibrink, B. A. B. Versluys, M. van der Heiden-van der Loo, M. van Gorp, G. A. Huizinga, M. A. Grootenhuis
Summary: This study examined the support needs and associated factors of young adult childhood cancer survivors (YACCS) in the Netherlands. The results showed that YACCS had the strongest need for concrete information in the domains of lifestyle, fertility, and physical consequences of childhood cancer. The associated factors were mainly socioeconomic and psychosocial in nature. The study suggests that psychosocial care should be integrated into survivorship care for YACCS.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Anna M. Jones, Emily K. Browne, Kristen Adams, Brian S. Potter, Valerie McLaughlin Crabtree, Niki Jurbergs, R. Elyse Heidelberg, Rachel Tillery Webster
Summary: This study examined the role of transition-focused psychology appointments in preparing families for the transition off therapy. The results showed that caregivers experienced distress during the transition, but those who had received psychology consultations and cognitive assessments felt more informed and prepared, leading to decreased distress.
Article
Oncology
Stephanie C. Gehle, Daniel Kleissler, Hillary Heiling, Allison Deal, Zongli Xu, Vanessa L. Ayer Miller, Jack A. Taylor, Andrew B. Smitherman
Summary: A study found that young adult cancer survivors have higher biological aging markers and experience accelerated aging. Measurement of biological age can help identify high-risk survivors and enhance our understanding of mechanisms underlying this accelerated aging.
Review
Oncology
Silvie H. M. Janssen, Winette T. A. van der Graaf, Daniel J. van der Meer, Eveliene Manten-Horst, Olga Husson
Summary: Adolescent and young adult (AYA) cancer patients, aged 15-39 years old, face unique challenges in their disease trajectory. Although the number of AYA cancer survivors has increased, they are at risk of long-term and late effects. Research efforts are needed to inform survivorship care for this growing population.
Article
Oncology
Chelsea J. Siwik, Kinnari Jhaveri, Jamie Alexis Cohen, Mikela Barulich, Alison Chang, Anna O. Levin, Neha G. Goyal, Michelle Melisko, Margaret A. Chesney, Dianne Shumay
Summary: This study evaluated the acceptability and preliminary outcomes of a group intervention called Survivorship Wellness Group Program (SWGP) in cancer centers. The results showed that SWGP is an acceptable and replicable model that can improve quality of life, reduce mental health symptoms, and increase knowledge in multiple domains of wellness for cancer survivors.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Heleen Maurice-Stam, Loes M. E. van Erp, Anne Maas, Hedy A. van Oers, Leontien C. M. Kremer, Eline Van Dulmen-den Broeder, Wim J. E. Tissing, Jacqueline J. Loonen, Helena J. H. van der Pal, Laura R. Beek, Andrica C. H. de Vries, Marry M. Van den Heuvel-Eibrink, Cecile M. Ronckers, Dorine Bresters, Marloes Louwerens, Margriet Van der Heiden-van der Loo, Gea A. Huizinga, Martha A. Grootenhuis
Summary: This study aimed to compare the psychosocial development of young adult survivors of childhood cancer with a norm group of young adults from the general population. The results showed that the overall psychosocial development of the young adult survivors of childhood cancer was as favorable as the norm group, but survivors of central nervous system cancer were at risk of an unfavorable psychosocial development in all domains.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Public, Environmental & Occupational Health
Eric Adjei Boakye, Katherine M. Polednik, Teresa L. Deshields, Arun Sharma, Yamile Molina, Lidia Schapira, Justin M. Barnes, Nosayaba Osazuwa-Peters
Summary: This study examined emotional distress in cancer survivors diagnosed as adolescents or young adults compared to survivors diagnosed as middle/older adults and the general population without a history of cancer. The findings showed that emotional distress was more prevalent among young adult cancer survivors than middle/older adult survivors. However, there was no difference in emotional distress between young adult cancer survivors and the general population without cancer.
ANNALS OF EPIDEMIOLOGY
(2022)
Article
Clinical Neurology
Miryam Yusufov, Christopher Recklitis, Eric S. Zhou, Traci N. Bethea, Lynn Rosenberg
Summary: Black women are underrepresented in insomnia research and cancer treatments may affect the sleep of cancer survivors. This study investigated the Insomnia Severity Index in a large cohort of Black women, finding strong internal consistency reliability but mixed results in factor structure analysis. Despite variations in previous studies, a one-factor structure was identified, suggesting potential differences in ISI measurement properties across samples and populations.
JOURNAL OF SLEEP RESEARCH
(2022)
Article
Oncology
Chantel Cacciotti, Lydia Larocque Chevalier, Cheryl Medeiros-Nancarrow, Christopher Recklitis, Tabitha M. Cooney
Summary: The identity of adult survivors of pediatric CNS tumors is linked to their health outcomes, with survivor identity associated with diagnosis and treatment, while victim identity is associated with poorer mental health. Frequency of thoughts of diagnosis is significantly associated with poorer mental health, anxiety, depression, and neurocognitive impairments. Understanding the unique features of identity in this population is important for patient-centered care.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Oncology
Lydia L. Chevalier, Eric K. Zwemer, Robert Casey, Christopher J. Recklitis
Summary: The majority of pediatric cancer survivors identified as survivors, which was associated with higher anxiety and worse overall mental health. A small percentage who identified as victims were more likely to engage in binge drinking and had poorer overall mental health. This suggests that assumptions about survivor identity and health outcomes in adult-onset cancer cannot be generalized to pediatric cancer populations.
JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY
(2022)
Article
Psychology, Social
Lydia L. Chevalier, Elizabeth Fine, Aditi Sharma, Eric S. Zhou, Christopher J. Recklitis
Summary: Insomnia is a common late effect of cancer, but many survivors have limited access to effective treatment. To address this issue, researchers developed a single-session intervention for insomnia after cancer. Preliminary results demonstrate the potential effectiveness of this program in improving survivors' insomnia symptoms.
JOURNAL OF PSYCHOSOCIAL ONCOLOGY
(2023)
Article
Clinical Neurology
Samlau Kutana, Sheila N. Garland, Eric S. Zhou
Summary: This article discusses the existing research on internet-delivered cognitive behavioral therapy for insomnia (iCBT-I) and identifies three critical gaps in the next wave of clinical trials. It focuses on iCBT-I interventions with automated delivery of clinical content, rather than CBT-I-based telemedicine interventions involving synchronous clinician participation.
CURRENT SLEEP MEDICINE REPORTS
(2023)
Article
Medicine, General & Internal
Andrea L. Fidler, Julie Waitt, Leslie E. Lehmann, Jo M. Solet, Jeanne F. Duffy, Brian D. Gonzalez, Dean W. Beebe, David A. Fedele, Eric S. Zhou
Summary: Noise and light levels during hospitalizations can disrupt sleep and circadian health, particularly for children undergoing stem cell transplants. This study found that the average overnight sound level was 55 dB, with an average of 3.4 loud noises per night. Children spent a significant amount of time in nonoptimal lighting, and the lowest recorded overnight noise level exceeded sleep recommendations. Improving the sleep and circadian health of patients, especially those at higher risk for health complications, should be a priority for hospitals.
JOURNAL OF HOSPITAL MEDICINE
(2023)
Article
Clinical Neurology
Sheila N. Garland, Joshua Tulk, Riley Cotter, Eric S. Zhou, Lauren C. Daniel, Fiona S. M. Schulte, Jacqueline L. Bender, Karine Chalifour, Geoff Eaton
Summary: This study describes sleep issues in young adults and analyzes potential demographic and clinical characteristics related to sleep quality. The results show that psychological distress is associated with worse sleep quality and sleep medication use in young adult cancer survivors. This may be a possible target for future research and intervention to promote long-term function and recovery.
Article
Clinical Neurology
Megan Clegg-Kraynok, Lauren Barnovsky, Eric S. Zhou
Summary: This study found that there is a problem with timely adherence to paper-based sleep diaries, which can result in biased event recall. The participants greatly over-reported their adherence, but only 37.1% of diary entries were completed within the instructed timeframe. This poses a challenge for researchers and clinicians utilizing sleep diaries in clinical trials and therapy for insomnia.
Article
Public, Environmental & Occupational Health
Eric S. Zhou, Anna Revette, Lee M. Ritterband, Traci N. Bethea, Lauren Delp, Patricia D. Simmons, Lynn Rosenberg
Summary: Insomnia disorder is highly prevalent among Black women. Cognitive-behavioral therapy for insomnia (CBT-I) is considered the optimal treatment, but very little efficacy research has been conducted in minority populations. Culturally tailoring intervention content may increase participant engagement and improve treatment outcomes.
TRANSLATIONAL BEHAVIORAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Alexis L. Michaud, Briana Bice, Eva Miklos, Katherine McCormick, Cheryl Medeiros-Nancarrow, Eric S. Zhou, Christopher J. Recklitis
Summary: Young adult cancer survivors often experience chronic insomnia, and traditional cognitive behavioral therapy for insomnia (CBTI) is not readily available to them. To address this issue, the Sleep Treatment Education Program for Young Adult Cancer Survivors (STEP-YA) was developed as a low-intensity educational intervention delivered virtually online. This phase 2 trial aims to evaluate the efficacy of STEP-YA in improving insomnia symptoms and mood in young adult cancer survivors, as well as the utility of individualized coaching in enhancing treatment effects.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Oncology
Eric S. Zhou, Ariana F. Valenzuela, Rebecca Robbins, Jessica M. Page, Kira Bona
Summary: This study aimed to understand the parent's experience in the sleep domain during maintenance therapy for pediatric ALL patients. The results showed that parents felt unprepared to manage sleep disruptions and had limited knowledge about the issue despite consistent provider communication. Clear messaging and behavioral intervention may help empower parents to support their child's sleep health during ALL treatment.
JOURNAL OF PEDIATRIC HEMATOLOGY-ONCOLOGY NURSING
(2023)
Article
Oncology
Eric S. Zhou, Anna Revette, Julie Waitt, Leslie E. Lehmann, Lisa R. Diller, Karen M. Emmons, Ariana F. Valenzuela, Susan Redline
Summary: Through focus groups with pediatric SCT nurses, we gained insights into their perspective on patient sleep and circadian disruptions, their efforts to minimize these disruptions, and their suggestions for improvement.
PEDIATRIC BLOOD & CANCER
(2023)
Review
Oncology
Jordan Gilleland Marchak, Salome Christen, Renee L. Mulder, Katja Baust, Johanna M. C. Blom, Tara M. Brinkman, Iris Elens, Erika Harju, Nina S. Kadan-Lottick, Joel W. T. Khor, Jurgen Lemiere, Christopher J. Recklitis, Claire E. Wakefield, Lori Wiener, Louis S. Constine, Melissa M. Hudson, Leontien C. M. Kremer, Roderick Skinner, Janine Vetsch, Jennifer L. Lee, Gisela Michel
Summary: The clinical practice guideline aims to harmonize international recommendations for mental health surveillance in survivors of childhood, adolescent, and young adult cancer. It strongly recommends mental health surveillance for all survivors of these cancers at every follow-up visit and prompt referral to mental health specialists when problems are identified.
Article
Psychology, Social
Eric S. Zhou, Manan M. Nayak, Peter R. Chai, Ilana M. Braun
Summary: The study found that the majority of cancer patients use medicinal cannabis to improve sleep, reporting better sleep initiation and quality, decreased use of sleep medications, and overall improved health as a result. No participants reported ineffectiveness or undesirable side effects when using medicinal cannabis for sleep.
JOURNAL OF PSYCHOSOCIAL ONCOLOGY
(2022)