Article
Nutrition & Dietetics
Md Mustahsan Billah, Saroj Khatiwada, Virginie Lecomte, Margaret J. Morris, Christopher A. Maloney
Summary: This study investigated the effects of an antioxidant-based micronutrient supplement on sperm and testicular oxidative damage in male rats fed a high-fat diet. The results suggest that the supplement may reduce oxidative damage in sperm and testis and improve testicular antioxidant capacity.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Cell Biology
Saroj Khatiwada, Virginie Lecomte, Michael F. Fenech, Margaret J. Morris, Christopher A. Maloney
Summary: Obesity increases the risk of metabolic disorders partly due to oxidative stress. A dietary micronutrient supplement with antioxidant and methyl donor activities showed positive effects on weight control, glucose metabolism, and liver function, reducing insulin resistance regardless of high-fat diet intake.
Article
Ecology
Clara Cooper-Mullin, Scott R. McWilliams
Summary: During bird migration, the duration of stopover is influenced by the fuel stores and antioxidant capacity of the birds, and this is also dependent on their migration strategy. Seasonal variation affects the body condition, antioxidant capacity, and timing and success of migration for birds at stopover sites.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2022)
Article
Biochemistry & Molecular Biology
Ana-Maria Vlasceanu, Daniela Gradinaru, Miriana Stan, Viorela G. Nitescu, Daniela Luiza Baconi
Summary: This study examined the relationship between serum cotinine levels and oxidative stress in 76 adult patients. The results showed an inverse association between tobacco smoke exposure and glutathione levels, suggesting that exposure to smoke particulate components can deplete systemic glutathione. Interestingly, active smokers had higher glutathione levels but lower levels of advanced oxidation protein products (AOPPs), while passive smokers showed a decrease in AOPP levels with an increase in glutathione levels. This suggests that inhalation of smoke particulate constituents can disrupt redox homeostasis and impair the antioxidant role of glutathione.
Review
Nutrition & Dietetics
Vladimira Foteva, Joshua J. Fisher, Yixue Qiao, Roger Smith
Summary: Molybdenum is a vital trace element that plays a role in various metabolic reactions. Its intake varies globally, primarily through diet, and supplementation is uncommon. The benefits of molybdenum for diabetes and oxidative stress are reported, but its effect on chronic diseases remains uncertain. It is important to understand molybdenum intake during pregnancy due to increased micronutrient demand and its impact on gestational outcomes.
Article
Biochemistry & Molecular Biology
Chang Liu, Qi Yan, Chao Gao, Liangru Lin, Jingyan Wei
Summary: The study confirmed the good antioxidant effect of rhGPx1, but it had immunogenicity in mice and its antioxidant effect was not as good as rmGPx1.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Erick Bahena Culhuac, Mona M. M. Y. Elghandour, Moyosore J. Adegbeye, Alberto Barbabosa-Pliego, Abdelfattah Z. M. Salem
Summary: This review analyzed the effect of dietary selenium on oxidative stress in horses by considering past and recent bibliographic sources. The findings suggest that selenium, as an important antioxidant, can regulate oxidative stress in horses when the body is under stress.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Arman Rahimmi, Sima Tozandehjani, Mona Daraei, Mohammadbagher Khademerfan
Summary: Parkinson's disease is a neurodegenerative disease strongly associated with cellular processes such as oxidative stress, neuro-inflammation, apoptosis, and mitochondrial dysfunction. Studies have shown that certain dietary micronutrients have protective effects against Parkinson's disease.
MOLECULAR BIOLOGY REPORTS
(2022)
Article
Plant Sciences
Naznin Ahmed, Khussboo Rahman, Mira Rahman, Khadeja Sultana Sathi, Md Mahabub Alam, Kamrun Nahar, Md Shahidul Islam, Mirza Hasanuzzaman
Summary: The bioregulator thiourea is effective in mitigating the negative impact of abiotic stresses on plants. This study found that thiourea application improved growth, oxidative stress tolerance, and protection of photosynthetic pigments in chickpea plants under drought stress.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Yue Liu, Zheng Chen, Ben Li, Hua Yao, Martin Zarka, Jeffrey Welch, Perminder Sachdev, Wallace Bridge, Nady Braidy
Summary: Supplementation with gamma-GC decreased brain lipid peroxidation, protein carbonyls, and apoptosis, while increasing total GSH levels and enhancing antioxidant enzyme activities. Additionally, gamma-GC improved Aβ pathology and cognitive function in APP/PS1 mice.
NEUROCHEMISTRY INTERNATIONAL
(2021)
Article
Psychiatry
Gianluca Pandolfo, Giovanni Genovese, Antonio Bruno, Domenica Campolo, Valeria Tigano, Mariateresa Cristani, Marco Casciaro, Giovanni Pioggia, Sebastiano Gangemi
Summary: The pathophysiology of schizophrenia is still not well understood. Genetic factors and oxidative stress play key roles in its development and progression. Oxidative stress leads to the continuous production of oxidation products, such as AGEs and AOPPs, which interact with their receptors, amplifying the production of reactive oxygen species (ROS) and pro-inflammatory cytokines. In this study, plasma levels of AGEs and AOPPs were found to be significantly higher in schizophrenia patients compared to controls, confirming their involvement in mental disorders. Antioxidant nutraceuticals and a healthy lifestyle could reduce oxidative stress and alleviate schizophrenia symptoms.
PSYCHIATRY RESEARCH
(2022)
Article
Neurosciences
Kathleen F. Holton
Summary: This article discusses how excitotoxicity, oxidative stress, and neuroinflammation interact to form a neurotoxic triad, and how specific dietary micronutrients can protect against them. Future dietary interventions may focus on the effects on all three aspects of the neurotoxic triad.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Qunying Jiang, Min Pan, Jialing Hu, Junlin Sun, Lei Fan, Zhiqiao Zou, Jianshuang Wei, Xiaoquan Yang, Xiaoqing Liu
Summary: The article discusses a highly effective phototherapy method that inhibits tumor growth and metastasis by regulating redox homeostasis using a biocompatible and versatile nanotherapeutic. By eliminating the endogenous ROS scavenging system, the phototherapy is amplified, leading to effective suppression of tumor growth both in vitro and in vivo. This innovative approach may offer a clinically relevant method for cancer treatment.
Review
Behavioral Sciences
Geir Bjorklund, Massimiliano Peana, Michael Maes, Maryam Dadar, Beatrice Severin
Summary: Redox dysfunctions and neuro-oxidative stress play a major role in the pathophysiology and progression of Parkinson's disease (PD). Lowered GSH metabolism and a low GSH/GSSG ratio following oxidative stress are associated with mitochondrial dysfunctions and neuroinflammatory processes accompanying PD. Antioxidant approaches may have therapeutic efficacy in treating PD and its progression by neutralizing reactive oxygen species.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Fisheries
Kristin Hamre, Giulia Micallef, Marie Hillestad, Johan Johansen, Sofie Remo, Wuxiao Zhang, Elisabeth Odegard, Pedro Araujo, Antony J. Prabhu Philip, Rune Waagbo
Summary: The hypothesis of this study was that increased growth in spring, stimulated by temperature and daylength, leads to oxidative stress and changes in antioxidant utilization in Atlantic salmon. The study found that vitamin E and vitamin C concentrations decreased in the spring and were restored in the autumn, while astaxanthin concentration remained constant during the spring and summer and increased in the autumn. Cataract and melanin spots were observed during the spring and early summer. However, the concentrations of malondialdehyde and astaxanthin did not support the hypothesis, and more data is needed to draw conclusions on the effects of oxidative stress on melanin spots.
Article
Hospitality, Leisure, Sport & Tourism
Athanasios Kabasakalis, Stefanos Nikolaidis, George Tsalis, Vassilis Mougios
Summary: This study aimed to evaluate and compare the effects of two low-volume sprint interval swimming sets on blood biomarkers. The results showed that both sets increased blood biomarkers, with the higher volume set causing greater increases.
RESEARCH QUARTERLY FOR EXERCISE AND SPORT
(2022)
Article
Biochemistry & Molecular Biology
Nikolaos Lemonakis, Vassilis Mougios, Maria Halabalaki, Ioanna Dagla, Anthony Tsarbopoulos, Alexios-Leandros Skaltsounis, Evagelos Gikas
Summary: This study aimed to investigate the effect of an olive leaf extract enriched with Oleuropein on the metabolome of young healthy male athletes. The results showed that the extract could influence the metabolism of tryptophan and acylcarnitine, enhance serotonin turnover, and possibly improve athletic performance.
Article
Sport Sciences
George Tsalis, Vassilis Mougios
Summary: The COVID-19 pandemic significantly affected swimming training, leading to reduced training duration and distance. However, the study found that the impact was not significant in terms of the number of young swimmers qualifying for national championships and their swimming performance, except for a slight decrease in male performance in the 400-m freestyle event.
Article
Immunology
Evaggelos-Georgios Stampinas, Efterpi Bouroutzika, Panagiotis D. Katsoulos, Georgios Valiakos, Ekaterini K. Theodosiadou, Labrini Athanasiou, Sotiria Makri, Demetrios Kouretas, Irene Valasi
Summary: This study aimed to evaluate the fluctuation of redox status after the administration of a clostridial vaccine in pregnant ewes and investigate the effect of Vit E/Se. The results showed that vaccination affected the antioxidant capacity but did not induce significant oxidative stress.
Article
Biochemistry & Molecular Biology
Konstantina Petraki, Maria G. Grammatikopoulou, Fotios Tekos, Zoi Skaperda, Marina Orfanou, Robin Mesnage, Tonia Vassilakou, Demetrios Kouretas
Summary: This study assessed the changes in the redox status of military pilots during flight simulation conditions. The results showed that experienced pilots had significantly increased levels of GSH and reduced levels of TAC after flight simulation, while novice pilots had increased levels of CAT and TAC. No significant differences were observed in TBARS and PCs levels post-simulation. In addition, TAC and PCs levels were significantly lower in novice pilots compared to experienced pilots.
Article
Biochemistry & Molecular Biology
Zoi Skaperda, Ioannis D. Kyriazis, Fotios Tekos, Maria Alvanou, Paraskevi-Maria Nechalioti, Sotiria Makri, Angeliki Argyriadou, Sotiria Vouraki, Theodoros Kallitsis, Maria Kourti, Valasi Irene, Georgios Arsenos, Demetrios Kouretas
Summary: The study aimed to assess the resting values of oxidative stress in lambs and kids reared in Greece and the correlation between redox biomarkers in blood and other tissues. The results showed that lambs and kids at different weight categories had varying levels of antioxidant defense systems. Blood redox biomarkers were associated with the ones measured in other tissues. These findings suggest that blood antioxidant parameters can be used as potential biomarkers to predict tissue antioxidant status and improve meat quality.
Article
Biochemistry & Molecular Biology
Maria Kourti, Maria V. V. Alvanou, Zoi Skaperda, Fotis Tekos, Georgios Papaefstathiou, Panagiotis Stathopoulos, Demetrios Kouretas
Summary: An extract from brine samples obtained through the Greek style debittering process of Kalamon olive fruits showed strong antioxidant capacity and DNA-protective activity. The extract consisted mainly of hydroxytyrosol, verbascoside, and tyrosol. In cell-free assays, the extract demonstrated radical scavenging ability, while in cell cultures, it exhibited cell type specific responses and protected against H2O2-induced DNA damage. Overall, this study highlights the potential of table olive wastewaters as a valuable source of bioactive compounds for various industries.
Article
Biochemistry & Molecular Biology
Fotios Tekos, Zoi Skaperda, Periklis Vardakas, Despina Kyriazi, Georgios C. C. Maravelis, Konstantinos Poulas, Ioannis A. A. Taitzoglou, Charitini Nepka, Demetrios Kouretas
Summary: Wine and its by-products, such as grape stems, contain bioactive polyphenolic compounds that can potentially benefit animal and human health. However, there are limited studies on the safety and toxicological risks of these compounds in vivo. This study examined the effects of oral administration of grape stem and wine extracts on redox biomarkers in mice and rats. The results showed that grape stem extract improved redox homeostasis in mice, while wine extract had both beneficial and harmful effects on rat redox status, indicating the complexity of biological systems.
Article
Biochemistry & Molecular Biology
Emmanouil Karampinis, Athina-Maria Aloizou, Efterpi Zafiriou, Alexandra Bargiota, Zoi Skaperda, Demetrios Kouretas, Angeliki-Viktoria Roussaki-Schulze
Summary: UV radiation has both harmful and beneficial effects on skin health. It can cause oxidative stress, leading to skin cancer and photoaging. However, it is also necessary for the production of vitamin D, which has important antioxidant and anticancer properties. This study found that skin cancer patients have lower levels of vitamin D and increased oxidative stress.
Article
Sport Sciences
Nikolaos Georgogiannis, George Tsalis
Summary: This study investigated the effect of a post-activation potentiation (PAP) protocol with simulated ground starts on swimming start and 25 m freestyle performance. The results showed that performing simulated swim starts 15 s or 8 min before the swim sprint had no positive effect on swimming start or performance.
JOURNAL OF FUNCTIONAL MORPHOLOGY AND KINESIOLOGY
(2023)
Article
Sport Sciences
Maria Mavroudi, Athanasios Kabasakalis, Anatoli Petridou, Vassilis Mougios
Summary: This study examined the blood lactate response of highly trained swimmers to different sprint distances. The findings suggest that the maximal lactate accumulation rate (VLamax) is highest after a 50m sprint, while swimming speed and VLamax are highest after a 25m sprint. Improving VLamax through training may enhance swimming performance.
Article
Health Care Sciences & Services
Nikolaos Paramanidis, Athanasios Kabasakalis, Nikolaos Koutlianos, George Tsalis, Evangelia Kouidi
Summary: This study investigated the relationship between shoulder pain and trunk muscle endurance in young swimmers. The results showed that strengthening the back and oblique muscles can reduce shoulder pain and disability in swimmers.
Review
Health Care Sciences & Services
George Tsalis, Glykeria Kyriakidou
Summary: Exercise in water is widely used to improve physical capacities of individuals with intellectual disabilities (IDs). This review examined the effects of water interventions on functional abilities, physiological status, and biochemical markers in people with IDs. A total of 15 studies published between 2010 and 31 December 2022 were included. Findings revealed incomplete data on exercise intensity and timing, varied terminology used to describe physical abilities, and conflicting results regarding balance and body mass index. Further research with accurate training load data and standardized fitness terminology is needed. Traditional swimming should be considered as an aquatic intervention.
Article
Sport Sciences
Konstantinos Papadimitriou, Athanasios Kabasakalis, Anastasios Papadopoulos, Georgios Mavridis, Georgios Tsalis
Summary: This study compared the acute responses to Ultra-Short Race Pace Training (USRPT) and High-Intensity Interval Training (HIIT) for the 100m freestyle event. The results showed that USRPT achieved higher swimming velocity compared to HIIT, but had lower distance per stroke and stroke index. Additionally, USRPT resulted in lower blood lactate and glucose concentrations, as well as lower heart rate and rate of perceived exertion.
Article
Health Care Sciences & Services
Maria Koumenidou, Mariana C. Kotzamanidou, Vassilios Panoutsakopoulos, Panagiotis Siaperas, Victoria Misailidou, George A. Tsalis
Summary: Individuals with High-Functioning Autism face challenges in communication, social interaction, and motor development. The effects of regular swimming exercise and aquatic therapy on health promotion in adults with High-Functioning Autism are still unclear. A 6-month swimming and aquatic therapy program for a 22-year-old male with High-Functioning Autism showed improvements in physical fitness and some motor skills, but the participant lost interest and focus quickly.