Journal
JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Volume 77, Issue 1, Pages 41-50Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.jri.2006.12.003
Keywords
antiphospholipid syndrome; lupus anticogulans; anticardiolipin antibodies; recurrent pregnancy loss; fetal loss
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The association of persistent presence of circulating antiphospholipid antibodies and thromboembolic events, (recurrent) pregnancy loss or both is termed antiphospholipid syndrome. Pregnancies in women with the syndrome should be regarded as at high-risk for complications. Optimal management consisting of close follow-up and pharmacological treatment can result in about 70-80% live births. Apart from the laboratory diagnosis of the syndrome and pathophysiology, this review will focus on treatment during pregnancy. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
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