Article
Engineering, Biomedical
Siyi Zhu, Yi Li, Liqiong Wang, Jinming Huang, Kangping Song, Xinling Gan, Xiaona Xiang, Chengqi He, Lin Yang
Summary: This study investigates the effectiveness of pulsed electromagnetic fields (PEMFs) for the management of primary osteoporosis in older adults. The results show that PEMFs are non-inferior to conventional pharmacological agents and exercise in preventing bone density decline and improving balance function. These effects are observed directly after intervention and at 12- and 24-week follow-ups.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2022)
Article
Orthopedics
Marco Vigano, Carlotta Perucca Orfei, Enrico Ragni, Alessandra Colombini, Laura de Girolamo
Summary: This systematic review and meta-analysis evaluated the effect of electromagnetic field treatment on knee osteoarthritis symptoms. It found that pulsed electromagnetic field therapy effectively relieves knee OA symptoms at short term, but is not superior to other conservative therapies such as physiotherapy.
Article
Medicine, General & Internal
Liang Ou, Yingfu Meng, Zehua Chen, Tiantian Zhang, Dezhong Kong, Daoqing Xu, Weichen Huang
Summary: This study aims to evaluate the effectiveness and safety of Chinese herbal fumigation for the treatment of knee osteoarthritis, providing high-quality evidence to support clinical practice.
Article
Orthopedics
Yuanjun Ma, Xiaohua Chen, Feng He, Shi Li, Rui He, Qian Liu, Qingshan Dong, Shuncheng Zhou, Hui Miao, Qian Lu, Feifei Li, Hongxu Yang, Mian Zhang, Yuan Lin, Shibin Yu
Summary: This study found that pulsed electromagnetic field (PEMF) exposure has a protective effect on subchondral bone in the early stage of TMJOA, and may act through the canonical Wnt/β-catenin pathway.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Review
Oncology
Mengqian Huang, Parker Li, Feng Chen, Zehao Cai, Shoubo Yang, Xiaohong Zheng, Wenbin Li
Summary: This review summarizes the five significant underlying mechanisms and applications of ELF-PEMF in the treatment of gliomas, as well as discusses the prospects of combining ELF-PEMF with conventional therapy for treating gliomas.
Review
Biochemistry & Molecular Biology
Jake Littman, Roy K. Aaron
Summary: Notable characteristics of the skeleton include its response to physical stimuli and ability to remodel in different environments. Cells in bones and cartilage can sense physical cues and activate genes to synthesize structural molecules. This review explores the response of a model system of bone formation to an externally applied pulsed electromagnetic field (PEMF), focusing on cell differentiation and extracellular matrix synthesis. The study emphasizes the dosage and tissue response mechanisms, which can guide the design of clinically optimal stimulation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Jonas Flatscher, Elizabeth Pavez Lorie, Rainer Mittermayr, Paul Meznik, Paul Slezak, Heinz Redl, Cyrill Slezak
Summary: Environmental biophysical interactions have a significant impact on trauma recovery processes in the human body. Studies on Pulsed Electromagnetic Fields (PEMF) have provided insights into their effects on the human body, cells, and biological systems. However, the diverse study setups have made it challenging to interpret commonalities and understand the underlying mechanisms of this treatment. This review provides a comprehensive overview of the published literature on PEMF, offering a scaffolded summary for future research and clinical use, and highlighting the need for common reporting parameters.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Sport Sciences
Qianlin Weng, Siew-Li Goh, Jing Wu, Monica S. M. Persson, Jie Wei, Aliya Sarmanova, Xiaoxiao Li, Michelle Hall, Michael Doherty, Ting Jiang, Chao Zeng, Guanghua Lei, Weiya Zhang
Summary: Exercise has similar effects on pain and function to that of oral NSAIDs and paracetamol. Given its excellent safety profile, exercise should be given more prominence in clinical care, especially in older people with comorbidity or at higher risk of adverse events related to NSAIDs and paracetamol.
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Article
Food Science & Technology
Hubert Arteaga, Ana Carolina de Sousa Silva, Caio Eduardo de Campos Tambelli, Sergio Souto, Ernane Jose Xavier Costa
Summary: This study evaluates the preservation effects of pulsed magnetic field (PMF)-assisted freezing on blueberries and their bioactive compounds. The results show that PMF-assisted freezing can preserve the cellular structures and bioactive compounds of blueberries, and promote higher antioxidant capacity.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Yuanjun Ma, Feng He, Xiaohua Chen, Shuncheng Zhou, Rui He, Qian Liu, Hongxu Yang, Jing Zhang, Mian Zhang, Hui Miao, Shibin Yu
Summary: The study found that PEMF treatment can reverse certain changes in cartilage degeneration and synovial inflammation in the early stage of TMJOA, including the loss of cartilage extracellular matrix, chondrocyte death, and up-regulation of pro-inflammatory and degradative factors. This treatment may be a promising method in clinical TMJOA treatment.
JOURNAL OF ORAL REHABILITATION
(2023)
Review
Biochemistry & Molecular Biology
Laura Caliogna, Marta Medetti, Valentina Bina, Alice Maria Brancato, Alberto Castelli, Eugenio Jannelli, Alessandro Ivone, Giulia Gastaldi, Salvatore Annunziata, Mario Mosconi, Gianluigi Pasta
Summary: This article reviews the signaling pathways modulated by PEMFs and their clinical applications, based on studies from PubMed and Embase. While identifying cell membrane receptors and pathways involved in bone healing, further research and clinical trials are needed to understand the dose-response relationship and practical applications of PEMFs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Public, Environmental & Occupational Health
Chuan Sun, Zheng Huang, Houbing Qin, Jing Zhang, Sanying Wang, Xiaogang Xu, Shibo Ying, Genxiang Mao
Summary: Rapid population aging has led to a global burden of late-life diseases, with aging being a major risk factor for age-related diseases and closely related to both genotype and external factors. Exposure to 10 Hz pulsed magnetic fields for 2 weeks induced DNA damage in cellular senescence, highlighting the potential impact of electromagnetic fields on aging.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Clinical Neurology
Andrew K. Chan, Alexander Ballatori, Priya Nyayapati, Nikhil V. Mummaneni, Dezba Coughlin, Ellen Liebenberg, Fabrice A. Kulling, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Jeffrey C. Lotz
Summary: The study demonstrated that PEMF accelerates sensorimotor recovery in a rodent model of disc herniation, suggesting that it may be a viable option for clinical management of herniation-associated radiculopathy.
Article
Biochemistry & Molecular Biology
Christina M. Wolff, Juergen F. Kolb, Sander Bekeschus
Summary: In modern oncology, combining different therapies to enhance treatment efficacy is a common approach. The combination of microsecond-pulsed electric fields and cold physical plasma treatment has shown synergistic effects, increasing the accumulation of reactive oxygen species (ROS), enhancing cytotoxicity against cancer cells, and promoting immune responses.
Review
Medicine, General & Internal
Zeling Huang, Xiao Mao, Junming Chen, Junjun He, Shanni Shi, Miao Gui, Hongjian Gao, Zhenqiang Hong
Summary: This study aims to evaluate the efficacy and safety of sinomenine hydrochloride injection in the treatment of knee osteoarthritis (KOA) through a systematic review and meta-analysis.