Role of high-mobility group box-1 protein in disruption of vascular barriers and regulation of leukocyte–endothelial interactions

Andrographolide inhibits HMGB1-induced inflammatory responses in human umbilical vein endothelial cells and in murine polymicrobial sepsis

(2014) W. Lee et al.   Acta Physiologica

Interleukin-1β induces an inflammatory response and the breakdown of the endothelial cell layer in an improved human THBMEC-based in vitro blood–brain barrier model

(2014) Josephine Labus et al.   JOURNAL OF NEUROSCIENCE METHODS

A Dual-Role of Gu-4 in Suppressing HMGB1 Secretion and Blocking HMGB1 Pro-Inflammatory Activity during Inflammation

(2014) HuiTing Zhou et al.   PLoS One

Cellular Mechanisms of High Mobility Group 1 (HMGB-1) Protein Action in the Diabetic Retinopathy

(2014) Andrea Rachelle C. Santos et al.   PLoS One

Acute hyperglycemia worsens ischemic stroke-induced brain damage via high mobility group box-1 in rats

(2013) Jingyang Huang et al.   BRAIN RESEARCH

Anti-septic Effects of Pellitorine in HMGB1-Induced Inflammatory Responses In Vitro and In Vivo

(2013) Sae-Kwang Ku et al.   INFLAMMATION

Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo

(2013) Hayoung Yoo et al.   INFLAMMATION RESEARCH

The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

(2013) Huan Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Selective Permeabilization of the Blood–Brain Barrier at Sites of Metastasis

(2013) John J. Connell et al.   JNCI-Journal of the National Cancer Institute

Role of the Acidic Tail of High Mobility Group Protein B1 (HMGB1) in Protein Stability and DNA Bending

(2013) Fabricio S. Belgrano et al.   PLoS One

High-mobility group box-1 protein activates inflammatory signaling pathway components and disrupts retinal vascular-barrier in the diabetic retina

(2012) Ghulam Mohammad et al.   EXPERIMENTAL EYE RESEARCH

Barrier protective effects of rosmarinic acid on HMGB1-induced inflammatory responses in vitro and in vivo

(2012) Eun-Ju Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

(2012) Milena Schiraldi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HMGB1 and leukocyte migration during trauma and sterile inflammation

(2012) Emilie Venereau et al.   MOLECULAR IMMUNOLOGY

Intranasal Delivery of HMGB1 siRNA Confers Target Gene Knockdown and Robust Neuroprotection in the Postischemic Brain

(2012) Il-Doo Kim et al.   MOLECULAR THERAPY

Recombinant thrombomodulin improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat LPS model

(2012) Toshiaki Iba et al.   THROMBOSIS RESEARCH

HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation

(2011) José Augusto Nogueira-Machado et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

HMGB1 Increases Permeability of the Endothelial Cell Monolayer via RAGE and Src Family Tyrosine Kinase Pathways

(2011) Wenchang Huang et al.   INFLAMMATION

Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood–Brain Barrier From Ischemia-Induced Disruption in Rats

(2011) Jiyong Zhang et al.   STROKE

High-Mobility Group Box 1, Oxidative Stress, and Disease

(2010) Daolin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E–Deficient Mice

(2010) Peter Kanellakis et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HMGB1 activates nuclear factor-κB signaling by RAGE and increases the production of TNF-α in human umbilical vein endothelial cells

(2010) Zheng-Gang Luan et al.   IMMUNOBIOLOGY

HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption

(2010) Rachel K. Wolfson et al.   MICROVASCULAR RESEARCH

Statins attenuate high mobility group box-1 protein induced vascular endothelial activation : a key role for TLR4/NF-κB signaling pathway

(2010) Jun Yang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Neuroprotection by biodegradable PAMAM ester (e-PAM-R)-mediated HMGB1 siRNA delivery in primary cortical cultures and in the postischemic brain

(2009) Il-Doo Kim et al.   JOURNAL OF CONTROLLED RELEASE

TGF-β Is Required for Vascular Barrier Function, Endothelial Survival and Homeostasis of the Adult Microvasculature

(2009) Tony E. Walshe et al.   PLoS One

The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction

(2009) Britta Engelhardt et al.   Seminars in Immunopathology

Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo

(2008) Loreto P. Véliz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)

(2008) Judy R. van Beijnum et al.   ANGIOGENESIS

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE