Mangiferin in cancer chemoprevention and treatment: pharmacokinetics and molecular targets

Norathyriol suppresses transformation in JB6 P+ cells by the inhibition of Akt

(2013) Jixia Li et al.   Journal of Cancer Research and Therapeutics

Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and β-catenin signaling pathway

(2013) Hongzhong Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer

(2012) Muthu K. Shanmugam et al.   CANCER LETTERS

Mangiferin exerts hepatoprotective activity against D-galactosamine induced acute toxicity and oxidative/nitrosative stress via Nrf2–NFκB pathways

(2012) Joydeep Das et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mangiferin induces apoptosis by suppressing Bcl-xL and XIAP expressions and nuclear entry of NF-κB in HL-60 cells

(2011) Kaori Shoji et al.   ARCHIVES OF PHARMACAL RESEARCH

Multifaceted link between cancer and inflammation

(2011) Gautam Sethi et al.   BIOSCIENCE REPORTS

Gallic acid indanone and mangiferin xanthone are strong determinants of immunosuppressive anti-tumour effects of Mangifera indica L. bark in MDA-MB231 breast cancer cells

(2011) Dagmar García-Rivera et al.   CANCER LETTERS

Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases

(2011) J. Li et al.   CANCER RESEARCH

 -Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth

(2011) J. J. Johnson et al.   CARCINOGENESIS

Pharmacokinetic study of mangiferin in human plasma after oral administration

(2011) Shaoying Hou et al.   FOOD CHEMISTRY

D(+) galactosamine induced oxidative and nitrosative stress-mediated renal damage in rats via NF-κB and inducible nitric oxide synthase (iNOS) pathways is ameliorated by a polyphenol xanthone, mangiferin

(2011) Manoranjan Ghosh et al.   FREE RADICAL RESEARCH

Mangifera indicaL. extract (Vimang) and mangiferin reduce the airway inflammation and Th2 cytokines in murine model of allergic asthma

(2011) Dagmar García Rivera et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer

(2011) Muthu Shanmugam et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Chemopreventive mechanisms of methionine on inhibition of benzo(a)pyrene–DNA adducts formation in human hepatocellular carcinoma HepG2 cells

(2011) Taehyun Roh et al.   TOXICOLOGY LETTERS

Cytotoxicity, cell cycle arrest, and apoptosis in breast cancer cell lines exposed to an extract of the seed kernel of Mangifera pajang (bambangan)

(2010) Mohd Fadzelly Abu Bakar et al.   FOOD AND CHEMICAL TOXICOLOGY

Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer

(2010) Anupam Bishayee   Frontiers in Bioscience-Landmark

Polyphenols with Antiulcerogenic Action from Aqueous Decoction of Mango Leaves (Mangifera indica L.)

(2009) Juliana Aparecida Severi et al.   MOLECULES

Cytoprotective Effect of Mangiferin on Benzo(a)pyrene-Induced Lung Carcinogenesis in Swiss Albino Mice

(2008) Peramaiyan Rajendran et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Protective Role of Mangiferin against Benzo(a)pyrene Induced Lung Carcinogenesis in Experimental Animals

(2008) Peramaiyan Rajendran et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Chemopreventive efficacy of mangiferin against benzo(a)pyrene induced lung carcinogenesis in experimental animals

(2008) Peramaiyan Rajendran et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Cytoprotective and antigenotoxic potential of Mangiferin, a glucosylxanthone against cadmium chloride induced toxicity in HepG2 cells

(2008) B.S. Satish Rao et al.   FOOD AND CHEMICAL TOXICOLOGY

Effect of mangiferin on benzo(a)pyrene induced lung carcinogenesis in experimental Swiss albino mice

(2008) P. Rajendran et al.   NATURAL PRODUCT RESEARCH