Journal
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
Volume 34, Issue 5, Pages 338-341Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/10799893.2014.896383
Keywords
Diseases; microRNAs; miR-107; signaling pathways
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Funding
- 985 Project Foundation of Sun Yat-Sen (The Hundred Talents Program Foundation) [88000-3311300]
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MicroRNAs exert their biologic effects by targeting specific mRNAs for degradation or translational inhibition. MicroRNA-mediated regulation is complex, potentially affecting expression of the host gene, related enzymes within the same pathway or apparently distinct targets. miR-107 is found to be implicated in the pathogenesis of some diseases. This review was performed to sum up the role of miR-107 and its signaling pathways in renal diseases.
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