On the expanding terminology in the GPCR field: The meaning of receptor mosaics and receptor heteromers

Adenosine receptors interacting proteins (ARIPs): Behind the biology of adenosine signaling

(2009) Francisco Ciruela et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function

(2009) Graeme Milligan   BRITISH JOURNAL OF PHARMACOLOGY

Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis

(2009) Kjell Fuxe et al.   CURRENT OPINION IN PHARMACOLOGY

Dimerization in GPCR mobility and signaling

(2009) Martin J Lohse   CURRENT OPINION IN PHARMACOLOGY

Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer

(2009) Juan José Fung et al.   EMBO JOURNAL

Integrated signaling in heterodimers and receptor mosaics of different types of GPCRs of the forebrain: relevance for schizophrenia

(2009) Kjell Fuxe et al.   JOURNAL OF NEURAL TRANSMISSION

Metabotropic glutamate type 5, dopamine D2and adenosine A2areceptors form higher-order oligomers in living cells

(2009) Nuria Cabello et al.   JOURNAL OF NEUROCHEMISTRY

Minireview: GPCR and G Proteins: Drug Efficacy and Activation in Live Cells

(2009) Jean-Pierre Vilardaga et al.   MOLECULAR ENDOCRINOLOGY

Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation

(2009) Yang Han et al.   Nature Chemical Biology

Building a new conceptual framework for receptor heteromers

(2009) Sergi Ferré et al.   Nature Chemical Biology

Cellular assays as portals to seven-transmembrane receptor-based drug discovery

(2009) Terry P. Kenakin   NATURE REVIEWS DRUG DISCOVERY

Receptor–receptor interactions: A novel concept in brain integration

(2009) Luigi F. Agnati et al.   PROGRESS IN NEUROBIOLOGY

‘7TM Receptor Allostery: Putting Numbers to Shapeshifting Proteins

(2009) Terry P. Kenakin   TRENDS IN PHARMACOLOGICAL SCIENCES

Receptor–receptor interactions within receptor mosaics. Impact on neuropsychopharmacology

(2008) K. Fuxe et al.   BRAIN RESEARCH REVIEWS

Fluorescence-based methods in the study of protein–protein interactions in living cells

(2008) Francisco Ciruela   CURRENT OPINION IN BIOTECHNOLOGY

Dopamine D2 receptors form higher order oligomers at physiological expression levels

(2008) Wen Guo et al.   EMBO JOURNAL

Detection of higher-order G protein-coupled receptor oligomers by a combined BRET-BiFC technique

(2008) Jorge Gandia et al.   FEBS LETTERS

Allostery: Absence of a Change in Shape Does Not Imply that Allostery Is Not at Play

(2008) Chung-Jung Tsai et al.   JOURNAL OF MOLECULAR BIOLOGY

Fluorescence Resonance Energy Transfer Analysis of  2a-Adrenergic Receptor Activation Reveals Distinct Agonist-Specific Conformational Changes

(2008) A. Zurn et al.   MOLECULAR PHARMACOLOGY

Seven Transmembrane Receptors as Nature's Prototype Allosteric Protein: De-emphasizing the Geography of Binding

(2008) T. P. Kenakin   MOLECULAR PHARMACOLOGY

Identification of a serotonin/glutamate receptor complex implicated in psychosis

(2008) Javier González-Maeso et al.   NATURE

Conformational cross-talk between α2A-adrenergic and μ-opioid receptors controls cell signaling

(2008) Jean-Pierre Vilardaga et al.   Nature Chemical Biology

Detection of heteromerization of more than two proteins by sequential BRET-FRET

(2008) Paulina Carriba et al.   NATURE METHODS

Antagonistic cannabinoid CB1/dopamine D2 receptor interactions in striatal CB1/D2 heteromers. A combined neurochemical and behavioral analysis

(2008) Daniel Marcellino et al.   NEUROPHARMACOLOGY

Heterodimers and Receptor Mosaics of Different Types of G-Protein-Coupled Receptors

(2008) Kjell Fuxe et al.   PHYSIOLOGY

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

(2008) C. Altenbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct conformational changes in  -arrestin report biased agonism at seven-transmembrane receptors

(2008) A. K. Shukla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allostery: an illustrated definition for the ‘second secret of life’

(2008) Aron W. Fenton   TRENDS IN BIOCHEMICAL SCIENCES

GPCR monomers and oligomers: it takes all kinds

(2008) Vsevolod V. Gurevich et al.   TRENDS IN NEUROSCIENCES

Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors

(2008) Martin J. Lohse et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains

(2007) L.F. Agnati et al.   BRAIN RESEARCH REVIEWS