Neuroanatomical substrates involved in cannabinoid modulation of defensive responses

Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors

(2010) Vanessa de Paula Soares et al.   BEHAVIOURAL BRAIN RESEARCH

Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors

(2010) Plinio C. Casarotto et al.   BEHAVIOURAL PHARMACOLOGY

Modulation of NMDA and AMPA-mediated synaptic transmission by CB1 receptors in frontal cortical pyramidal cells

(2010) Qiang Li et al.   BRAIN RESEARCH

Cannabinoid CB1 receptors in the medial prefrontal cortex modulate the expression of contextual fear conditioning

(2010) Sabrina F. Lisboa et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Brain-Derived Neurotrophic Factor Controls Cannabinoid CB1 Receptor Function in the Striatum

(2010) V. De Chiara et al.   JOURNAL OF NEUROSCIENCE

Anxiolytic-like effect induced by the cannabinoid CB1 receptor agonist, arachydonilcyclopropylamide (ACPA), in the rat amygdala is mediated through the D1 and D2 dopaminergic systems

(2010) Mohammad Reza Zarrindast et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The Endocannabinoid 2-Arachidonoylglycerol Produced by Diacylglycerol Lipase α Mediates Retrograde Suppression of Synaptic Transmission

(2010) Asami Tanimura et al.   NEURON

The Endocannabinoid System Tonically Regulates Inhibitory Transmission and Depresses the Effect of Ethanol in Central Amygdala

(2010) Marisa Roberto et al.   NEUROPSYCHOPHARMACOLOGY

Facilitation of endocannabinoid effects in the ventral hippocampus modulates anxiety-like behaviors depending on previous stress experience

(2010) A.C. Campos et al.   NEUROSCIENCE

Localization and Function of the Cannabinoid CB1 Receptor in the Anterolateral Bed Nucleus of the Stria Terminalis

(2010) Nagore Puente et al.   PLoS One

Rapid elevations in limbic endocannabinoid content by glucocorticoid hormones in vivo

(2010) Matthew N. Hill et al.   PSYCHONEUROENDOCRINOLOGY

Distinct Effects of Δ9-Tetrahydrocannabinol and Cannabidiol on Neural Activation During Emotional Processing

(2009) Paolo Fusar-Poli et al.   ARCHIVES OF GENERAL PSYCHIATRY

Role of Endocannabinoid System in the Ventral Hippocampus of Rats in the Modulation of Anxiety-Like Behaviours

(2009) Ali Roohbakhsh et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Differential effects of chronic unpredictable stress on hippocampal CB1 receptors in male and female rats

(2009) Christian G. Reich et al.   BEHAVIOURAL BRAIN RESEARCH

Involvement of the prelimbic prefrontal cortex on cannabidiol-induced attenuation of contextual conditioned fear in rats

(2009) José Inácio Lemos et al.   BEHAVIOURAL BRAIN RESEARCH

Attenuation of anxiety-related behaviour after the antagonism of transient receptor potential vanilloid type 1 channels in the rat ventral hippocampus

(2009) Carolina J.P.A. Santos et al.   BEHAVIOURAL PHARMACOLOGY

Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression

(2009) Fabrício A. Moreira et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Endocannabinoid signals in the control of emotion

(2009) Beat Lutz   CURRENT OPINION IN PHARMACOLOGY

Potential anxiogenic effects of cannabinoid CB1 receptor antagonists/inverse agonists in rats: Comparisons between AM4113, AM251, and the benzodiazepine inverse agonist FG-7142

(2009) K.S. Sink et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Endocannabinoids render exploratory behaviour largely independent of the test aversiveness: role of glutamatergic transmission

(2009) W. Jacob et al.   GENES BRAIN AND BEHAVIOR

Cannabinoid Receptor Activation in the Basolateral Amygdala Blocks the Effects of Stress on the Conditioning and Extinction of Inhibitory Avoidance

(2009) E. Ganon-Elazar et al.   JOURNAL OF NEUROSCIENCE

From Threat to Fear: The Neural Organization of Defensive Fear Systems in Humans

(2009) D. Mobbs et al.   JOURNAL OF NEUROSCIENCE

Blockade of NMDA receptors and nitric oxide synthesis in the dorsolateral periaqueductal gray attenuates behavioral and cellular responses of rats exposed to a live predator

(2009) Daniele Cristina Aguiar et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Suppression of Amygdalar Endocannabinoid Signaling by Stress Contributes to Activation of the Hypothalamic–Pituitary–Adrenal Axis

(2009) Matthew N Hill et al.   NEUROPSYCHOPHARMACOLOGY

Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology

(2009) Sagnik Bhattacharyya et al.   NEUROPSYCHOPHARMACOLOGY

Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety

(2009) Michael Davis et al.   NEUROPSYCHOPHARMACOLOGY

Anxiety-like behavior induced by histaminergic agents can be prevented by cannabinoidergic WIN55,212-2 injected into the dorsal hippocampus in mice

(2009) Mohammad Reza Zarrindast et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory

(2009) P. Campolongo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids

(2009) Alline Cristina Campos et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats

(2009) Daniele C. Aguiar et al.   PSYCHOPHARMACOLOGY

Interactions between environmental aversiveness and the anxiolytic effects of enhanced cannabinoid signaling by FAAH inhibition in rats

(2009) J. Haller et al.   PSYCHOPHARMACOLOGY

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

(2009) Angelo A. Izzo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond

(2008) Roger G. Pertwee   ADDICTION BIOLOGY

The endocannabinoid system: emotion, learning and addiction

(2008) Fabrício A. Moreira et al.   ADDICTION BIOLOGY

Cannabinoid CB1 receptors of the rat central amygdala mediate anxiety-like behavior: interaction with the opioid system

(2008) Mohammad-Reza Zarrindast et al.   BEHAVIOURAL PHARMACOLOGY

Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test

(2008) Sabrina F. Lisboa et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Facilitation of contextual fear memory extinction and anti-anxiogenic effects of AM404 and cannabidiol in conditioned rats

(2008) Rafael M. Bitencourt et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Modulation of anxiety-like behaviour by Transient Receptor Potential Vanilloid Type 1 (TRPV1) channels located in the dorsolateral periaqueductal gray

(2008) Ana Luisa B. Terzian et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of corticotropin-releasing hormone signaling

(2008) K. Kamprath et al.   GENES BRAIN AND BEHAVIOR

Downregulation of the CB1 Cannabinoid Receptor and Related Molecular Elements of the Endocannabinoid System in Epileptic Human Hippocampus

(2008) A. Ludanyi et al.   JOURNAL OF NEUROSCIENCE

Cannabinoid Modulation of Amygdala Reactivity to Social Signals of Threat in Humans

(2008) K. L. Phan et al.   JOURNAL OF NEUROSCIENCE

Endocannabinoid modulation of fear responses: learning and state-dependent performance effects

(2008) CG Reich et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala

(2008) S. C. Azad et al.   LEARNING & MEMORY

Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

(2008) István Katona et al.   NATURE MEDICINE

Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum

(2008) Mauro Maccarrone et al.   NATURE NEUROSCIENCE

Cardiovascular and behavioral responses to conditioned fear after medullary raphe neuronal blockade

(2008) D.M.L. Vianna et al.   NEUROSCIENCE

Anxiolytic-like effects induced by acute reversible inactivation of the bed nucleus of stria terminalis

(2008) L.B.M. Resstel et al.   NEUROSCIENCE

Lack of effects of clomipramine on Fos and NADPH-diaphorase double-staining in the periaqueductal gray after exposure to an innate fear stimulus

(2008) Fabrício A. Moreira et al.   PHYSIOLOGY & BEHAVIOR

Activation of CB1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats

(2008) L. B. M. Resstel et al.   PSYCHOPHARMACOLOGY

Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats

(2008) Alline Cristina Campos et al.   PSYCHOPHARMACOLOGY

Role of the bed nucleus of the stria terminalis in the cardiovascular responses to acute restraint stress in rats

(2008) C. C. Crestani et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

FAAH and anandamide: is 2-AG really the odd one out?

(2008) Vincenzo Di Marzo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Antiaversive Effects of Cannabinoids: Is the Periaqueductal Gray Involved?

(2008) F. A. Moreira et al.   NEURAL PLASTICITY

CB1 receptor stimulation in specific brain areas differently modulate anxiety-related behaviour

(2007) T. Rubino et al.   NEUROPHARMACOLOGY

Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors

(2007) Fabricio A. Moreira et al.   NEUROPHARMACOLOGY

Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice

(2007) David J. Rademacher et al.   NEUROPHARMACOLOGY

Anxiolytic-like effects induced by medial prefrontal cortex inhibition in rats submitted to the Vogel conflict test

(2007) L.B.M. Resstel et al.   PHYSIOLOGY & BEHAVIOR