Electronic Connection Between the Quinone and Cytochrome c Redox Pools and Its Role in Regulation of Mitochondrial Electron Transport and Redox Signaling

Hybrid fusions show that inter-monomer electron transfer robustly supports cytochrome bc1 function in vivo

(2014) Robert Ekiert et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Organization of Cytochrome c2 near the Binding Domain of Cytochrome bc1 Studied by Electron Spin–Lattice Relaxation Enhancement

(2014) Rafał Pietras et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Triplet State of the Semiquinone–Rieske Cluster as an Intermediate of Electronic Bifurcation Catalyzed by Cytochrome bc1

(2013) Marcin Sarewicz et al.   BIOCHEMISTRY

A Robust Genetic System for Producing Heterodimeric Native and Mutant Cytochrome bc1

(2013) Bahia Khalfaoui-Hassani et al.   BIOCHEMISTRY

Intermonomer Electron Transfer between the b Hemes of Heterodimeric Cytochrome bc1

(2013) Pascal Lanciano et al.   BIOCHEMISTRY

Catalytically-relevant electron transfer between two hemes bL in the hybrid cytochrome bc1-like complex containing a fusion of Rhodobacter sphaeroides and capsulatus cytochromes b

(2013) Monika Czapla et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Key role of water in proton transfer at the Qo-site of the cytochrome bc1 complex predicted by atomistic molecular dynamics simulations

(2013) Pekka A. Postila et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Protein conformational changes involved in the cytochrome bc1 complex catalytic cycle

(2013) Jason W. Cooley   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Unanswered questions about the structure of cytochrome bc1 complexes

(2013) Edward A. Berry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Atomistic simulations indicate cardiolipin to have an integral role in the structure of the cytochrome bc1 complex

(2013) Sanja Pöyry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Functional role of mitochondrial respiratory supercomplexes

(2013) Maria Luisa Genova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The role of menaquinones (vitamin K2) in human health

(2013) Joline W. J. Beulens et al.   BRITISH JOURNAL OF NUTRITION

A Caged, Destabilized, Free Radical Intermediate in the Q-Cycle

(2013) Preethi R. Vennam et al.   CHEMBIOCHEM

Crystal structures and binding studies of atovaquone and its derivatives with cytochrome bc1: a molecular basis for drug design

(2013) Susanta K. Nayak et al.   CRYSTENGCOMM

Evidence for Cardiolipin Binding Sites on the Membrane-Exposed Surface of the Cytochrome bc1

(2013) Clement Arnarez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

(2013) E. Lapuente-Brun et al.   SCIENCE

Enzymatic Activities of Isolated Cytochrome bc1-like Complexes Containing Fused Cytochrome b Subunits with Asymmetrically Inactivated Segments of Electron Transfer Chains

(2012) Monika Czapla et al.   BIOCHEMISTRY

Design and use of photoactive ruthenium complexes to study electron transfer within cytochrome bc1 and from cytochrome bc1 to cytochrome c

(2012) Francis Millett et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Superoxide generation by complex III: From mechanistic rationales to functional consequences

(2012) Lea Bleier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Respiratory complex III dysfunction in humans and the use of yeast as a model organism to study mitochondrial myopathy and associated diseases

(2012) B. Meunier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Structural analysis of cytochrome bc1 complexes: Implications to the mechanism of function

(2012) Di Xia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Energy transduction by respiratory metallo-enzymes: From molecular mechanism to cell physiology

(2012) Sinan Al-Attar et al.   COORDINATION CHEMISTRY REVIEWS

Back-reactions, short-circuits, leaks and other energy wasteful reactions in biological electron transfer: Redox tuning to survive life in O2

(2012) A. William Rutherford et al.   FEBS LETTERS

Zinc Inhibition of Bacterial Cytochromebc1Reveals the Role of CytochromebE295 in Proton Release at the QoSite

(2011) Dong-Woo Lee et al.   BIOCHEMISTRY

Intermonomer Electron Transfer between the Low-PotentialbHemes of Cytochromebc1

(2011) Pascal Lanciano et al.   BIOCHEMISTRY

The Q cycle of cytochrome bc complexes: A structure perspective

(2011) William A. Cramer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

X-ray structure of the dimeric cytochrome bc1 complex from the soil bacterium Paracoccus denitrificans at 2.7-Å resolution

(2011) Thomas Kleinschroth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

New developments on the functions of coenzyme Q in mitochondria

(2011) Maria Luisa Genova et al.   BIOFACTORS

Unraveling the Biological Roles of Reactive Oxygen Species

(2011) Michael P. Murphy et al.   Cell Metabolism

The Mechanism of Superoxide Production by the Antimycin-inhibited Mitochondrial Q-cycle

(2011) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal Transduction by Mitochondrial Oxidants

(2011) Toren Finkel   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Reorientation of cytochrome c2 upon interaction with oppositely charged macromolecules probed by SR EPR: implications for the role of dipole moment to facilitate collisions in proper configuration for electron transfer

(2011) Marcin Sarewicz et al.   Metallomics

Design of anti-parasitic and anti-fungal hydroxy-naphthoquinones that are less susceptible to drug resistance

(2011) Louise M. Hughes et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Questioning the functional relevance of mitochondrial supercomplexes by time-resolved analysis of the respiratory chain

(2011) M. Trouillard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photosynthetic growth despite a broken Q-cycle

(2011) Alizée Malnoë et al.   Nature Communications

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation

(2010) Dominika Malinska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Discrimination between two possible reaction sequences that create potential risk of generation of deleterious radicals by cytochrome bc1

(2010) Marcin Sarewicz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Hypoxia and mitochondrial oxidative metabolism

(2010) Giancarlo Solaini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Guidelines for tunneling in enzymes

(2010) Christopher C. Moser et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Prevention of cardiolipin oxidation and fatty acid cycling as two antioxidant mechanisms of cationic derivatives of plastoquinone (SkQs)

(2010) Vladimir P. Skulachev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Occurrence, biosynthesis and function of isoprenoid quinones

(2010) Beatrycze Nowicka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Ubiquinol (QH 2 ) functions as a negative regulator of purine nucleotide inhibition of Acanthamoeba castellanii mitochondrial uncoupling protein

(2010) Andrzej Woyda-Ploszczyca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Inhibiting Plasmodium cytochrome bc1: a complex issue

(2010) Victoria Barton et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Tocopheryl quinones and mitochondria

(2010) Lars Gille et al.   MOLECULAR NUTRITION & FOOD RESEARCH

An Electronic Bus Bar Lies in the Core of Cytochrome bc1

(2010) M. Swierczek et al.   SCIENCE

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

(2010) Robert B. Hamanaka et al.   TRENDS IN BIOCHEMICAL SCIENCES

Roles for Vitamin K Beyond Coagulation

(2009) Sarah L. Booth   Annual Review of Nutrition

Uncoupling protein 1 inhibition by purine nucleotides is under the control of the endogenous ubiquinone redox state

(2009) Aleksandra Swida-Barteczka et al.   BIOCHEMICAL JOURNAL

Magnetic Interactions Sense Changes in Distance between HemebLand the Iron−Sulfur Cluster in Cytochromebc1

(2009) Marcin Sarewicz et al.   BIOCHEMISTRY

Across Membrane Communication between the Qoand QiActive Sites of Cytochromebc1†

(2009) Jason W. Cooley et al.   BIOCHEMISTRY

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: Synthesis and in vitro studies

(2009) Y. N. Antonenko et al.   BIOCHEMISTRY-MOSCOW

Mobility and function of Coenzyme Q (ubiquinone) in the mitochondrial respiratory chain

(2009) Giorgio Lenaz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Visualizing changes in electron distribution in coupled chains of cytochrome bc1 by modifying barrier for electron transfer between the FeS cluster and heme c1

(2009) Ewelina Cieluch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial DNA mutations and human disease

(2009) Helen A.L. Tuppen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain complexes I and III

(2009) Stefan Dröse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Modulation of the Mitochondrial Cytochrome bc1Complex Activity by Chromanols and Related Compounds

(2009) Andrea Müllebner et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The courtship of proteins: Understanding the encounter complex

(2009) Marcellus Ubbink   FEBS LETTERS

Direct Demonstration of Half-of-the-sites Reactivity in the Dimeric Cytochromebc1Complex

(2009) Michela Castellani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Potential Greatly Enhances Superoxide Generation by the Cytochromebc1Complex Reconstituted into Phospholipid Vesicles

(2009) Hagai Rottenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subnanomolar Inhibitor of Cytochromebc1Complex Designed by Optimizing Interaction with Conformationally Flexible Residues

(2009) Pei-Liang Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Menaquinone as pool quinone in a purple bacterium

(2009) B. Schoepp-Cothenet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Is CytochromebGlutamic Acid 272 a Quinol Binding Residue in thebc1Complex ofSaccharomyces cerevisiae?

(2008) Nadir Seddiki et al.   BIOCHEMISTRY

Movement of the Iron−Sulfur Head Domain of Cytochromebc1Transiently Opens the Catalytic QoSite for Reaction with Oxygen†

(2008) Arkadiusz Borek et al.   BIOCHEMISTRY

Regulatory interactions in the dimeric cytochrome bc1 complex: The advantages of being a twin

(2008) Raul Covian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Electron transfer kinetics between soluble modules of Paracoccus denitrificans cytochrome c1 and its physiological redox partners

(2008) Julia Janzon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Q-cycle reviewed: How well does a monomeric mechanism of the bc1 complex account for the function of a dimeric complex?

(2008) Antony R. Crofts et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Respiratory-chain diseases related to complex III deficiency

(2008) Paule Bénit et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Quinone and non-quinone redox couples in Complex III

(2008) Haibo Zhang et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Modification of quinone electrochemistry by the proteins in the biological electron transfer chains: examples from photosynthetic reaction centers

(2008) M. R. Gunner et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Prolonged α-Tocopherol Deficiency Decreases Oxidative Stress and Unmasks α-Tocopherol-dependent Regulation of Mitochondrial Function in the Brain

(2008) Sarah L. Cuddihy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Demonstration of Short-lived Complexes of Cytochromecwith Cytochromebc1by EPR Spectroscopy

(2008) Marcin Sarewicz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of Complex III with Bound Cytochromecin Reduced State and Definition of a Minimal Core Interface for Electron Transfer

(2008) Sozanne R. N. Solmaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanism of Mitochondrial Superoxide Production by the Cytochromebc1Complex

(2008) Stefan Dröse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protective Effects of Mitochondria-Targeted Antioxidant SkQ in Aqueous and Lipid Membrane Environments

(2008) Y. N. Antonenko et al.   JOURNAL OF MEMBRANE BIOLOGY

The Unusual Reaction of Semiquinone Radicals with Molecular Oxygen

(2008) Luca Valgimigli et al.   JOURNAL OF ORGANIC CHEMISTRY