Article
Chemistry, Multidisciplinary
Min-Han Hao, Selvaraj Nagarajan, Eamor M. Woo
Summary: This study used scanning electron microscopy and synchrotron radiation to analyze the crystal aggregates formed by poly(p-dioxanone) and poly(vinyl alcohol) during crystallization. The results showed that the periodic architectures were formed by alternating flat crystals and fibrils, with an oblique angle between the branches and the flat crystals.
Article
Chemistry, Physical
Selvaraj Nagarajan, Kuan-Ying Huang, Wei-Tsung Chuang, Jhih-Min Lin, Eamor M. Woo
Summary: Poly(p-dioxanone) (PPDO) is a bioabsorbable material commonly used in biomedical applications, with its crystal morphology dependent on temperature and polymorphism. PPDO can form ringless spherulites (RLS) and ring-banded spherulites (RBS) depending on the temperature, each with different crystal structures. The interior structure of PPDO-RBS consists of horizontal and vertical lamellae, and the growth patterns of ring bands can be customized.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Polymer Science
Kuan-Ying Huang, Eamor M. Woo, Selvaraj Nagarajan
Summary: Amorphous PVPh was added to semicrystalline PPDO to form a unique dendritic/ringed structure with periodic ring bands. The structure consisted of feather-like lamellae dividing into multiple branches following the Fibonacci sequence. The periodic ring bands were responsible for the formation of the unique dendritic/ringed PPDO structure.
Article
Polymer Science
Junlin Lu, Xulin Hu, Tianyu Yuan, Jianfei Cao, Yuanli Zhao, Chengdong Xiong, Kainan Li, Xun Ye, Tao Xu, Jizong Zhao
Summary: Novel 3D-printed bioresorbable stents (BRSs) for cerebrovascular disease have been designed and fabricated, enabling anti-stenosis and gradual disappearance after vessel endothelialization. The size and coverage of the stents can be controlled by adjusting printing parameters. PPDO monofilaments with improved hydrolytic stability and excellent mechanical properties have been used. Cell experiments have shown good proliferation ability and flexibility of the stents.
Article
Polymer Science
Kuan-Ying Huang, Yu-Zhe Huang, Li-Ting Lee, Eamor M. Woo
Summary: By using AFM and SEM, the study investigates the exterior and interior lamellar assemblies of PPDO crystallized at 76 degrees C. At T(c)s = 70-78 degrees C, PPDO displays dual-type birefringent spherulites, but becomes irregular and loses the capacity for light interference at T-c > 80 degrees C. The results reveal that periodic grating assemblies of PPDO possess iridescence features similar to nature's structural coloration, demonstrating the feasibility of grating assembly by orderly stacked crystal layers.
Article
Biochemistry & Molecular Biology
Laifa Tong, Mi Zhou, Yulong Chen, Kai Lu, Zhaohua Zhang, Yuesong Mu, Zejian He
Summary: In this study, a new biodegradable copolymer with self-healing abilities was synthesized through the Diels-Alder reaction between poly (p-dioxanone) (PPDO) and polylactide (PLA). Various chain segment lengths of copolymers were obtained by altering the molecular weights of PPDO and PLA precursors. The copolymerization effectively avoided the phase separation of PPDO and PLA, and showed improved crystallization performance and heat resistance compared to pure PLA. The copolymer also exhibited self-repairing properties and a degradation rate between that of PPDO and PLA.
Article
Chemistry, Multidisciplinary
Jin Lei, Zhu-Xin Gui, Wan-Ting Xiong, Gang Wu, Si-Chong Chen, Yu-Zhong Wang
Summary: By using phosphite compounds as end-capping reagents and chain extenders during the melt processing of poly(p-dioxanone) (PPDO), the thermal stability and crystallization of PPDO were significantly enhanced. The crystallization rate and monomer recovery of PPDO/phosphite compounds were also improved.
SCIENCE CHINA-CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Yi-Teng Yan, Gang Wu, Si-Chong Chen, Yu-Zhong Wang
Summary: A novel biodegradable copolymer was synthesized via chain extending reaction, and its structure, molecular weight, thermal stability, mechanical properties, and hydrolytic degradation behaviors were investigated.
CHINESE CHEMICAL LETTERS
(2022)
Article
Environmental Sciences
Fang Wang, Longfeng Wei, Meiting Guo, Wansheng Yang, Zhu Li, Deyu Hu, Ping Lu
Summary: This study investigated the effect of microorganisms on the degradation of BIT residues in different soil conditions using 16S rRNA gene sequencing. The results showed significant changes in the structure and abundance of bacterial communities in BIT soils, while there was no significant difference in the fungal community. Certain bacterial phyla played a crucial role in the degradation of BIT, and soil organic matter and pH had significant effects on the microbial community.
Article
Polymer Science
Zhiyan Xu, Jinling Liu, Jiawen Chen, Jianrong Lin, Qinhui Chen
Summary: The study focuses on using three different hydrophilic-lipophilic balance snowman-like Janus particles as compatibilizers for PPDO/PLA composites, improving interfacial adhesion through self-assembly. Among them, SiO2@PS-PMMA JPs exhibit the best interfacial behavior, significantly enhancing the mechanical properties of the composite materials.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Engineering, Biomedical
Fan Zhao, Jing Sun, Wen Xue, Fujun Wang, Martin W. King, Chenglong Yu, Yongjie Jiao, Kun Sun, Lu Wang
Summary: The recent advancement in bioresorbable stents offers a promising approach for treating coronary artery disease, but there is a need for further development of stents with better compression and degradation performance for pediatric patients with congenital heart disease. The mechanically self-reinforced composite bioresorbable stent developed in this study demonstrates excellent support and degradation performance in vivo.
BIOACTIVE MATERIALS
(2021)
Article
Engineering, Chemical
Yu-Zhe Huang, Eamor M. Woo, Selvaraj Nagarajan
Summary: The morphologies and arrangements of biodegradable polyesters, poly(p-dioxanone) (PPDO) blended with poly(ethylene succinate) (PESu), were studied. Three different types of nuclei were found in the PPDO/PESu blend system, and a novel technique was used to dissect the interior 3D structures of PPDO. The detailed 3D-assembly provides insights into the complexed architectures of this polymer.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2022)
Article
Polymer Science
Xu Zhang, Guanhao Chen, Liping Liu, Lingyuan Zhu, Zaizai Tong
Summary: The research demonstrates that size control of 2D PPDO platelets can be improved by modulating solvent compositions or elevating crystallization temperatures, leading to the creation of nanomaterials with precise size and shape control. Additionally, adjusting crystallization conditions can result in shape changes of 2D platelet micelles from quasi-square to lozenge shapes, as well as achieving spatially defined block comicelles. The excellent water stability and biocompatibility of the 2D PPDO platelet micelles further suggest their potential application as cargo vehicles in drug delivery.
Article
Engineering, Environmental
Roberto Altieri, Maurizia Seggiani, Alessandro Esposito, Patrizia Cinelli, Vitale Stanzione
Summary: The study found that raw collagen hydrolysates from the tannery industry can be used in the production of PBSA-based thermoplastic blends, creating compostable items with organic nitrogen fertilizing properties. This approach not only reduces production costs, but also provides a sustainable solution for agriculture and plant nurseries.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2021)
Article
Chemistry, Multidisciplinary
Wei Zhang, Guo-Qiang Tian, Gang Wu, Si-Chong Chen, Yu-Zhong Wang
Summary: In recent years, chemical recycling to monomer (CRM) has become an advanced strategy for dealing with post-consumer plastics. This work developed a Bronsted-Lewis acid ionic liquid/polyhydroxy-compound system as a bifunctional reagent for dissolving poly(p-dioxanone) (PPDO) and catalyzing its CRM. The efficiency and selectivity of CRM were improved by preventing the formation of byproducts and achieving almost complete depolymerization in a short time.